Results 81 to 90 of about 2,265,315 (182)

Virus‐specific alterations in placental structure and transporter expression following maternal arbovirus infection

The Journal of Physiology, EarlyView.
Abstract figure legend Arboviruses induce virus‐specific alterations in placental structure and functional markers. Chikungunya virus (CHIKV) exposure was associated with reduced syncytiotrophoblast and syncytial knot areas, increased cytotrophoblast proliferation (Ki‐67) and thyroid transporter (MCT8) expression, reduced protective (P‐gp and BCRP ...
Cherley B. V. Andrade, Enrrico Bloise, Natália L. Silva, Jair R. S. Braga, Sharton V. A. Coelho, Veronica M. O. Nascimento, Guinever E. Imperio, Camila O. S. Nunes, Antônio J. L. A. Cunha, Marcelo A. Pascoal‐Xavier, Luciana B. Arruda, Arnaldo Prata‐Barbosa, Kristin L. Connor, Tania M. Ortiga‐Carvalho   +13 more
wiley   +1 more source

A Situational Overview of Prenatal Screening Services in Bhutan

Public Health Challenges
Prenatal genetic testing is to determine the possibility of the fetus having a genetic aberration or birth defect. Prenatal screening consists of serum analytes screening with or without nuchal translucency (NT) scanning or with cell‐free DNA (CfDNA ...
Yeshey Dorjey, Tashi Gyeltshen, Thinley Dorji, Don Eliseo Lucero‐Prisno III, Mimi Lhamu Mynak, Sonam Gyamtsho, Tashi Tshomo, Phurb Dorji   +7 more
doaj   +1 more source

Global Recommendations for the Use of Diagnostic Genomic Sequencing in the Prenatal Setting on Behalf of the ESHG and ISPD

Prenatal Diagnosis, EarlyView.
Zandra C. Deans, Lina Basel Salmon, Kwong Wai Choy, Guido de Wert, Zirui Dong, Lilian Downie, Francesca Romana Grati, Sabine Hentze, Paula Jorge, Brynn Levy, Luca Lovrecic, Dora Mayen, Álvaro Mendes, Michael Morris, Ashley Pritchard, Raquel Gouveia Silva, Tina‐Marié Wessels, Francesca Forzano, Natalie J. Chandler   +18 more
wiley   +1 more source

Disparities in antenatal care utilization and stillbirth risk among women of other origin than high‐income Western countries in Stockholm 2000–2020: A retrospective cohort study

Acta Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 10, Page 2030-2040, October 2026.
Women of other origin than high‐income Western Countries, particularly women originating from sub‐Saharan Africa, had fewer antenatal care visits and a higher proportion of inpatient care occasions compared to women from high‐income Western Countries. Abstract Introduction Foreign‐born women face a higher risk of adverse pregnancy outcomes, including ...
Minna Lundén, Ingela Hulthén Varli, Helena Kopp Kallner, Hanna Åmark   +3 more
wiley   +1 more source

Can It Happen Again? Using Co‐Produced Theatre to Explore the Challenges Faced by Couples Considering Pregnancy After a De Novo Genetic Diagnosis in a Child

Health Expectations, Volume 29, Issue 5, October 2026.
ABSTRACT Introduction When a couple has a child with a genetic condition, it raises questions when considering future pregnancies. It has typically been considered an easier genetic test result to receive when the condition is de novo (new) in origin, because neither parent is understood to have passed on the genetic change, except in rare cases ...
Alison Kay, Anne Goriely, Alexa Gummow, Lisa Hinton, Arti Patel, Marysia Price‐Nowak, Shwetha Ramachandrappa, Jonathon Wells, Francesca Wicks, Minna Jeffery   +9 more
wiley   +1 more source

CHORIONIC VILLUS SAMPLING: A SAFE TOOL FOR PRENATAL DIAGNOSIS OF GENETIC DISORDERS

Pakistan Armed Forces Medical Journal, 2009
Objectives: To determine the safety and efficacy of chorionic villus sampling (CVS) for early prenatal diagnosis of genetic disorders. Study Design: Descriptive study.
Nadra Sultana, Zartaj Hayat, Iffat Nasim
doaj   +2 more sources

An Integrated Proteomics and Genomics Approach to Identify Essential Protein Kinases During Human Trophoblast Development

The FASEB Journal, Volume 40, Issue 17, 15 September 2026.
Integrated quantitative proteomic, phosphoproteomic, and transcriptomic analyses of human trophoblast stem cells identify stage‐specific kinase signaling networks that regulate trophoblast self‐renewal and differentiation into syncytiotrophoblasts and extravillous trophoblasts.
Rajnish Kumar, Purbasa Dasgupta, Soma Ray, Soumen Paul   +3 more
wiley   +1 more source

Placental Site Trophoblastic Tumor Acquires Immune Functions by Incorporating Host Maternal Genes

Advanced Science, Volume 13, Issue 50, 7 September 2026.
PSTT cells, through cell fusion with B cells, incorporate abundant non‐inherited maternal genes that are detectable by DNIMA. These hybrid cells acquire immunotherapy‐resistant genetic changes and increase the expression of B cell‐derived immune‐related molecules such as Ig, HLA, LILRB, SIGLEC10, and so on, creating an immunotolerant environment around
Kyosuke Kagami, Masanori Ono, Yasunari Mizumoto, Tatsuhito Kanda, Takashi Iizuka, Takiko Daikoku, Shin‐ichi Horike, Akira Hattori, Akihito Horie, Sachiko Minamiguchi, Tomoko Fujiwara, Kazuyoshi Hosomichi, Atsushi Tajima, Hirokazu Usui, Kaoru Abiko, Hiroshi Fujiwara   +15 more
wiley   +1 more source

Placental biomarkers of phthalate effects on mRNA transcription: application in epidemiologic research

Environmental Health, 2009
Background CYP19 and PPARγ are two genes expressed in the placental trophoblast that are important to placental function and are disrupted by phthalate exposure in other cell types.
Nelson Heather, Thaker Harshwardhan M, Whyatt Robin M, Williams Paige L, Hauser Russ, Adibi Jennifer J, Herrick Robert, Bhat Hari K   +7 more
doaj   +1 more source

Maternal‐Fetal Administration of Risdiplam Partially Rescues the SMNΔ7 Mouse Model of Spinal Muscular Atrophy

Annals of Neurology, Volume 100, Issue 3, Page 584-599, September 2026.
Objective Spinal muscular atrophy (SMA) is caused by deletions or mutations in the survival motor neuron 1 (SMN1) gene and subsequent reduction in the expression of survival motor neuron (SMN) protein. The disease is characterized by degeneration of α motor neurons and subsequent muscle atrophy.
Emma R. Sutton, Ariane Beauvais, Rebecca Yaworski, Hugh J. McMillan, Rashmi Kothary   +4 more
wiley   +1 more source