Results 111 to 120 of about 57,466 (278)

Simplified Anisotropic IVIM Using Spherical Means and an Application in the Placenta

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To reduce the complexity associated with anisotropic IVIM modeling, we derived two simplified diffusion MRI models that map the apparent diffusivity, relative proportions, and anisotropy of perfusion‐ and diffusion‐related signal components and demonstrated them in placenta scans.
Paddy J. Slator   +8 more
wiley   +1 more source

Intrauterine growth in multiple pregnancies in relation to fetal number, chorionicity and gestational age

open access: yes, 2008
Objectives To examine birth weight lit (dichorionic and monochorionic twins and trichorionic triplets, and to estimate the relative independent importance on growth of fetal number, chorionicity and gestational age.
Nicolaides, K. H.   +7 more
core   +1 more source

Monochorionic Diamniotic Twins with Sex Discordance: Case Series

open access: yesDiagnostics
Background and Clinical Significance: Ultrasonographic diagnosis of twin pregnancies has become routine, with chorionicity playing a crucial role in assessing associated risks. Traditionally, monochorionic (MC) twins were believed to derive from a single
Valentina Sala   +7 more
doaj   +1 more source

Hemophilia A: An Ideal Disease for Prenatal Therapy

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Hemophilia A (HA) is the most common inherited coagulation defect. Current state‐of‐the‐art treatment consists of frequent administration of prophylactic infusions of coagulation factor VIII (FVIII) protein or bispecific antibodies that replace the cofactor function of FVIIIa to maintain hemostasis. However, these treatments are far from ideal,
Christopher D. Porada   +2 more
wiley   +1 more source

Monozygotic Pregnancies Following Assisted Reproductive Technology: A Review

open access: yesEuropean Medical Journal Reproductive Health, 2016
Introduction: Assisted reproductive technology (ART) is associated with an increased risk of monozygotic twinning. This narrative review attempts to summarise the known literature regarding the aetiology, incidence, risk factors, diagnosis, and prognosis
Mariano Mascarenhas, Keerthi Gnanaprabha
doaj  

Attitudes Toward Prenatal Interventions in the Fanconi Anemia Community

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Objective In‐utero cell and gene therapies may offer prenatal treatment options for inherited diseases. Preclinical data suggests in‐utero (IU) hematopoietic stem cell transplantation (HSCT) could prevent Fanconi anemia (FA) related bone marrow failure without genotoxic conditioning or immune suppression.
Tony Lum   +4 more
wiley   +1 more source

In Utero HSC Transplantation for Sickle Cell Disease: A Potential Therapeutic Approach That Overcomes Complications of Current Therapies

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Sickle cell disease (SCD) affects millions worldwide but has limited treatment options, most of which carry significant side effects. At present, the only curative treatment for SCD is allogeneic or gene‐modified autologous hematopoietic stem cell (HSC) transplantation (Tx).
Oluwaseun O. Babatunde   +4 more
wiley   +1 more source

CURRENT APPROACHES TO MANAGEMENT OF MULTIPLE PREGNANCIES

open access: yesАкушерство, гинекология и репродукция, 2016
A clinical lecture presents the current management of multiple pregnancies, modern diagnostics and treatment of complications in this high risk group of patients.
L. G. Sichinava
doaj  

Perinatal outcomes and growth discordance of triplet pregnancies based on chorionicity: a retrospective cohort study

open access: yesBMC Pregnancy and Childbirth
Background The worldwide occurrence of triplet pregnancy is estimated to be 0.093%, with a natural incidence of approximately 1 in 8000. This study aims to analyze the neonatal health status and birth weight discordance (BWD) of triplets based on ...
Qing Hu   +5 more
doaj   +1 more source

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