Results 221 to 230 of about 57,466 (278)

MIS12 Is Required for Kinetochore‐Microtubule Attachment in Oocyte Meiosis

open access: yesAdvanced Science, Volume 13, Issue 51, 14 September 2026.
A model depicting the role of MIS12 in K‐MT attachment during oocyte meiosis. The presence of MIS12 stabilizes bipolar K‐MT attachments by maintaining the function of NDC80 and its interaction with TUBB. This, in turn, promotes KNL1 assembly and subsequent SAC protein recruitment to kinetochores.
Jian Li   +9 more
wiley   +1 more source

Maternal‐Fetal Administration of Risdiplam Partially Rescues the SMNΔ7 Mouse Model of Spinal Muscular Atrophy

open access: yesAnnals of Neurology, Volume 100, Issue 3, Page 584-599, September 2026.
Objective Spinal muscular atrophy (SMA) is caused by deletions or mutations in the survival motor neuron 1 (SMN1) gene and subsequent reduction in the expression of survival motor neuron (SMN) protein. The disease is characterized by degeneration of α motor neurons and subsequent muscle atrophy.
Emma R. Sutton   +4 more
wiley   +1 more source

Jacobs Syndrome Presenting With Delayed Puberty and Central Hypogonadism: A Rare Case Report

open access: yesClinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT In some rare instances, patients with 47,XYY syndrome can be short in height, accompanied by hypogonadism without the characteristic tall stature. In cases where there is delayed puberty and unusual growth pattern, a complete endocrine work‐up, including GnRH and hCG stimulation tests, along with chromosome studies, is vital.
Muhammad Hassaan Javaid   +4 more
wiley   +1 more source

Premature Ductus Arteriosus Constriction and Pulmonary Trunk Dilation in a Case of Non‐Immune Hydrops Fetalis With Trisomy 21

open access: yesClinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Premature constriction of the ductus arteriosus accompanied by the dilation of the pulmonary trunk constitutes a rare congenital heart anomaly that may be underestimated and can result in fetal hydrops and ultimately death if not treated; therefore, it necessitates fetal post‐mortem evaluation in all cases of legal abortion or fetal death.
Nazari Mohadeseh   +2 more
wiley   +1 more source

Norethisterone‐Associated Decidual Cast Expulsion Mimicking an Acute Gynecologic Emergency: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Decidual cast is a rare benign condition that may mimic acute gynecologic emergencies. It should be suspected in patients with severe colicky pain followed by sudden relief after tissue expulsion, especially with progestin use such as norethisterone. Accurate diagnosis and histopathology prevent unnecessary surgery.
Tuka Hamasho   +5 more
wiley   +1 more source

Impact of chorionicity on birth weight discordance in twins. [PDF]

open access: yesTransl Pediatr
Li Q   +5 more
europepmc   +1 more source

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