Results 71 to 80 of about 10,527 (218)

Kineochelins—A New Group of Siderophores From an Antarctic Bacterium

Microbial Biotechnology, Volume 19, Issue 6, June 2026.
Genome‐guided analysis of an Antarctic Actinokineospora strain led to the discovery of kineochelins, a new group of siderophores involved in iron sequestration and microbial competition. Kineochelin production inhibits co‐occurring bacteria and clinically relevant yeasts, highlighting Antarctic microorganisms as promising sources of bioactive natural ...
Stanislava Kralova, Peter Spacek, Johannes Gafriller, Matej Bezdicek, Viktoria Medvedcova, Joana Séneca, Jay Osvatic, Ulrike Grienke, Thomas Rattei, Olga N. Sekurova, Sergey B. Zotchev, Martin Zehl, Alexander Loy   +12 more
wiley   +1 more source

Selection of Heterodera glycines Chorismate Mutase-1 Alleles on Nematode-Resistant Soybean

Molecular Plant-Microbe Interactions, 2005
The soybean cyst nematode Heterodera glycines is the most destructive pathogen of soybean in the Unites States. Diversity in the parasitic ability of the nematode allows it to reproduce on nematode-resistant soybean. H.
Kris N. Lambert, Sadia Bekal, Leslie L. Domier, Terry L. Niblack, Gregory R. Noel, Charles A. Smyth   +5 more
doaj   +1 more source

The DENN Protein SMD1 Forms a Signalling Hub With Rab GTPase YPT1 to Regulate Diverse Biological Processes in Phytopathogenic Fungi and Serves as a HIGS Target for Crop Protection

Molecular Plant Pathology, Volume 27, Issue 6, June 2026.
The DENN domain‐containing protein SsSMD1 is highly conserved across phytopathogenic fungi. Functioning as a putative GEF for RAS GTPase SsYPT1, SsSMD1 orchestrates its activation to regulate cell wall integrity, sclerotia development, and virulence in Sclerotinia sclerotiorum.
Cheng Zhang, Lin Li, Sunhong Liu, Yan Xu, Xin Li, Yuelin Zhang   +5 more
wiley   +1 more source

A Chorismate Mutase from the Soybean Cyst Nematode Heterodera glycines Shows Polymorphisms that Correlate with Virulence

Molecular Plant-Microbe Interactions, 2003
Parasitism genes from phytoparasitic nematodes are thought to be essential for nematode invasion of the host plant, to help the nematode establish feeding sites, and to aid nematodes in the suppression of host plant defenses.
Sadia Bekal, Terry L. Niblack, Kris N. Lambert   +2 more
doaj   +1 more source

Host‐Induced Silencing of Rhizoctonia Solani 5‐Enolpyruvylshikimate‐3‐Phosphate Synthase Impairs Its Virulence in Rice

Plant Biotechnology Journal, Volume 24, Issue 6, Page 3573-3593, June 2026.
ABSTRACT Sheath blight disease of rice caused by the fungal pathogen R. solani AG1‐IA remains a big threat to rice production worldwide. A limited genetic variation in rice for tolerance to this pathogen and little success in understanding how it defeats host defence are major reasons behind it.
Vinod Kumar, Apoorva Prasad, Akshita Goel, Vijay Kumar Sharma, Jagjeet Singh Lore, Arun Kumar   +5 more
wiley   +1 more source

Targeting upstream and downstream arms of the bacterial shikimate metabolic network as an opportunity for antibacterial and antivirulence therapy

Discover Bacteria
The shikimate pathway is an essential metabolic route in bacteria that generates chorismate, a central intermediate linking primary metabolism to the biosynthesis of aromatic amino acids and diverse infection-relevant metabolites.
Reuben S. Maghembe
doaj   +1 more source

Metabolic dependency of chorismate in Plasmodium falciparum [PDF]

, 2019
The shikimate pathway, a metabolic pathway absent in humans, is responsible for the production of chorismate, a branch point metabolite. In the malaria parasite, chorismate is postulated to be a direct precursor in the synthesis of p -aminobenzoic acid (folate biosynthesis), p
Valenciano, Ana Lisa, Fernández-Murga, Maria L., Merino, Emilio F., Holderman, Nicole R., Butschek, Grant J., Shaffer, Karl J., Tyler, Peter C., Cassera, Maria Belen   +7 more
openaire   +2 more sources

Synthesis of Amines for Active Pharmaceutical Ingredients Using the Whole‐Cell Factory Saccharomyces Cerevisae

ChemBioChem, Volume 27, Issue 9, 14 May 2026.
This review highlights advances in engineering Saccharomyces cerevisiae for the sustainable biocatalytic production of pharmaceutically relevant amines, amino alcohols, amino acids, and complex alkaloids. It focuses on strategies to increase productivity, including enhanced enzyme expression, cofactor regeneration, precursor channeling, pathway ...
Natalia Kwiatos, Stephen Ossel, Francesco G. Mutti   +2 more
wiley   +1 more source

Gap Analysis of Metabolic Conversions of Off‐Flavors and Antinutrients in Plant‐Based Substrates

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 3, May 2026.
ABSTRACT To drastically reduce the carbon footprint of the food production chain, a major shift towards alternatives to conventional meat and dairy products is required. The use of plant‐based proteins is a promising route, but it also comes with challenges: Plant‐based proteins often contain antinutritional factors and off‐flavors, which can ...
Robin I. Kuijpers, Isabel O. de Moya Clark, Tomás Cavaco, Vivian Nemanič, Beatrice Tagliabue, Ainhoa Valero‐Abad, Wiebe M. Wennekers, Mengqiu Zhang, Koen Van Zwet, Sanne Abeln, Sofia Moco, Caroline E. Paul, Halima Mouhib, Richard A. Notebaart, Eddy J. Smid, Bas Teusink, Herwig Bachmann   +16 more
wiley   +1 more source

Quantum chemical modeling of the reaction path of chorismate mutase based on the experimental substrate/product complex

FEBS Open Bio, 2017
Chorismate mutase is a well‐known model enzyme, catalyzing the Claisen rearrangement of chorismate to prephenate. Recent high‐resolution crystal structures along the reaction coordinate of this enzyme enabled computational analyses at unprecedented ...
D. Burschowsky, U. Krengel, E. Uggerud, David Balcells   +3 more
semanticscholar   +1 more source