Turn-Induction in Peptides Incorporating Novel Cyrene-Derived α,α-Disubstituted Amino Acid. [PDF]
Novel chiral cyrene‐derived Cyr residues were incorporated into peptides. The α,α‐disubstituted amino acid residue was introduced using the Ugi reaction. X‐ray crystallographic analysis of R‐ and S‐Cyr residues indicated preference to adopt left‐ and right‐handed α‐helical conformations, respectively.
Bhowal KB, Hitti R, Lubell WD.
europepmc +2 more sources
Desymmetrization of Malonic Monoesters and Malonic Acids via Enantioselective Catalytic C(sp<sup>3</sup>)─H Oxidation. [PDF]
Manganese‐catalyzed enantioselective C(sp3)─H lactonization with hydrogen peroxide enables the direct desymmetrization of malonic monoesters and malonic acids, providing highly enantioenriched γ‐ and δ‐lactones (up to >99% ee) ABSTRACT Malonate derivatives are readily available starting materials widely employed in the synthesis of bioactive compounds.
Siakavaras N +3 more
europepmc +2 more sources
Tomato-Soy Juice Reduces Inflammation and Modulates the Urinary Metabolome in Adults With Obesity. [PDF]
Compared to pre‐intervention, consuming a tomato‐soy juice (54 mg lycopene, 189 mg soy isoflavones/d) reduced levels of inflammatory cytokines (IL‐5, IL‐12p70, and GM‐CSF, with TNF‐alpha trending downward), increased plasma lycopene and urinary soy isoflavone metabolites, and altered the urinary metabolome. ABSTRACT Chronic, low‐grade inflammation is a
Sholola MJ +6 more
europepmc +2 more sources
The influence of nanoadditives in the synthesis of eco-friendly polyester plasticizers [PDF]
Plasticized polymer materials are widely used in all spheres of human life. The most common plasticizers are aromatic compounds-esters of o-phthalic acid.
A.K. Mazitova +5 more
doaj +1 more source
Due to its high nutritional value and broad beneficial effects, the artichoke plant (Cynara cardunculus L.) is an excellent healthy food candidate.
Mirco Vacca +7 more
doaj +1 more source
1-(Carbamoylmethyl)cyclohexanecarboxylic acid [PDF]
Molecules of the title compound, C9H15NO3, form a two-dimensional hydrogen-bonded network, via O—H⋯O and N—H⋯O interactions, which runs parallel to the bc plane. In this structure, neither the carboxylic acid groups nor the carbamoyl groups are involved in dimer formations.
Nagaraj, B. +3 more
openaire +2 more sources
Genome Sequence Analysis of the Naphthenic Acid Degrading and Metal Resistant Bacterium Cupriavidus gilardii CR3. [PDF]
Cupriavidus sp. are generally heavy metal tolerant bacteria with the ability to degrade a variety of aromatic hydrocarbon compounds, although the degradation pathways and substrate versatilities remain largely unknown.
Xiaoyu Wang +9 more
doaj +1 more source
Spanish-style table olives are one of the most common processed foods in the Mediterranean countries. Lack of control during fermentation can lead to one of the main defects of the olive, called ‘Zapateria’, caused by the combination of volatile fatty ...
Ramiro Sánchez +5 more
doaj +1 more source
An investigation of fecal volatile organic metabolites in irritable bowel syndrome. [PDF]
Diagnosing irritable bowel syndrome (IBS) can be a challenge; many clinicians resort to invasive investigations in order to rule out other diseases and reassure their patients.
Iftikhar Ahmed +4 more
doaj +1 more source
Metabolomics analyses of traditional Chinese medicine formula Shuang Huang Lian by UHPLC-QTOF-MS/MS
Background Shuang Huang Lian (SHL) is a traditional Chinese medicine (TCM) formula made from Lonicerae Japonicae Flos, Forsythiae Fructus, and Scutellariae Radix. Despite the widespread use of SHL in clinical practice for treating upper respiratory tract
Gang Xu, Yachun Shu, Yan Xu
doaj +1 more source

