Results 11 to 20 of about 2,071 (135)

Turn-Induction in Peptides Incorporating Novel Cyrene-Derived α,α-Disubstituted Amino Acid. [PDF]

J Pept Sci
Novel chiral cyrene‐derived Cyr residues were incorporated into peptides. The α,α‐disubstituted amino acid residue was introduced using the Ugi reaction. X‐ray crystallographic analysis of R‐ and S‐Cyr residues indicated preference to adopt left‐ and right‐handed α‐helical conformations, respectively.
Bhowal KB, Hitti R, Lubell WD.
europepmc   +2 more sources

Desymmetrization of Malonic Monoesters and Malonic Acids via Enantioselective Catalytic C(sp³)─H Oxidation. [PDF]

Angew Chem Int Ed Engl
Manganese‐catalyzed enantioselective C(sp3)─H lactonization with hydrogen peroxide enables the direct desymmetrization of malonic monoesters and malonic acids, providing highly enantioenriched γ‐ and δ‐lactones (up to >99% ee) ABSTRACT Malonate derivatives are readily available starting materials widely employed in the synthesis of bioactive compounds.
Siakavaras N, Call A, Bietti M, Costas M.   +3 more
europepmc   +2 more sources

A Snapshot, Using a Multi-Omic Approach, of the Metabolic Cross-Talk and the Dynamics of the Resident Microbiota in Ripening Cheese Inoculated with Listeria innocua [PDF]

Foods
Raw milk cheeses harbor complex microbial communities. Some of these microorganisms are technologically essential, but undesirable microorganisms can also be present.
Alessandra Tata, Andrea Massaro, Brunella Miano, Sara Petrin, Pietro Antonelli, Arianna Peruzzo, Alessandra Pezzuto, Michela Favretti, Marco Bragolusi, Carmela Zacometti, Carmen Losasso, Roberto Piro   +11 more
doaj   +2 more sources

Metabolomics in Traditional Chinese Medicine for Diabetes Mellitus: Mechanistic Insights, Biomarker Discovery, and Clinical Application Prospects. [PDF]

Int J Anal Chem
Objective This review provides a comprehensive summary of recent advancements in metabolomic analysis within traditional Chinese medicine (TCM) for the treatment of diabetes mellitus. It focuses on the standardized profiling of syndrome‐specific metabolites, the identification of bioactive compounds using high‐throughput techniques, and the elucidation
Song J, Li GL, Wu S, Li H.
europepmc   +2 more sources

Aerobic Growth of Rhodococcus aetherivorans BCP1 Using Selected Naphthenic Acids as the Sole Carbon and Energy Sources

Frontiers in Microbiology, 2018
Naphthenic acids (NAs) are an important group of toxic organic compounds naturally occurring in hydrocarbon deposits. This work shows that Rhodococcus aetherivorans BCP1 cells not only utilize a mixture of eight different NAs (8XNAs) for growth but they ...
Alessandro Presentato, Alessandro Presentato, Martina Cappelletti, Anna Sansone, Carla Ferreri, Elena Piacenza, Marc A. Demeter, Silvia Crognale, Maurizio Petruccioli, Giorgio Milazzo, Stefano Fedi, Alexander Steinbüchel, Alexander Steinbüchel, Raymond J. Turner, Davide Zannoni   +14 more
doaj   +1 more source

Water‐Derived Radical Species Initiate Six‐Electron Oxidation of Cyclic Ketones in Microdroplets

Angewandte Chemie, EarlyView.
Spontaneous six‐electron oxidation of cyclic ketones to yield dicarboxylic acids/keto acids is achieved in ethanol microdroplets containing about 2% water under ambient conditions without any metal salts, acids, or oxidants. Mechanistic studies show that trace amounts of water and molecular oxygen serve as active oxidants in this transformation ...
Muhammad Mujahid Ali, Manish Jana, William LeFever, Robert Graham Cooks   +3 more
wiley   +2 more sources

Bioactivity of ethanolic and hexanic extracts of Annona montana Macfad. in the control of Aphis craccivoraKoch (Hemiptera: Aphididae)

Pesquisa Agropecuária Tropical
The use of synthetic insecticides to control pests in agriculture may negatively affect the environment, human health, and contribute to the emergence of resistant pest populations.
Moisés Felix de Carvalho Neto, Antonio Cesar Silva Lima, Rita de Cássia Rodrigues Gonçalves-Gervásio, Antonio Alves de Melo Filho, Edigênia Cavalcante da Cruz Araújo   +4 more
doaj   +1 more source

Effect of cyclohexane carboxylic acid on the formation of aerobic granular sludge

Gongye shui chuli
Aerobic granular sludge(AGS) technology has shown certain application potential in the treatment of toxic and refractory organic matter in wastewater. However, it is unknown whether the formation process and stability of AGS are affected under long-term ...
LIU Shasha, LI Simeng, GENG Bao, LI Jin, WANG Qinghong, CHEN Chunmao   +5 more
doaj   +1 more source

Scutellarein Alleviates Ulcerative Colitis by Reshaping Gut Microbiota and Regulating the PRMT1‐Mediated Th17/Treg Balance

Food Frontiers, Volume 7, Issue 4, July 2026.
Scutellarein alleviates ulcerative colitis by reinforcing the intestinal barrier via the microbiota‐metabolite axis and suppressing PRMT1‐STAT3‐mediated inflammatory immune responses. ABSTRACT Ulcerative colitis (UC) is a chronic inflammatory disease of the colonic mucosa with an increasing global burden and limited therapeutic efficacy.
Yefan Zhou, Xinyu Xu, Huan Fang, Xue Wang, Jiaqi Hua, Linping Lu, Dongxu Li, Yangyang Wen, Jieqiong Yao, Fang Liu, Jing He, Fucheng He, Mingxia Zhou   +12 more
wiley   +1 more source

The Emerging Short Chain Fatty Acid Enriched Metabotype in Irritable Bowel Syndrome and Its Potential Clinical Relevance

Alimentary Pharmacology &Therapeutics, Volume 64, Issue 2, Page 208-221, July 2026.
In a cohort of IBS‐D patients recruited to the TRITON study, faecal metabolomic profiling reveals a SCFA‐enriched metabotype associated with increased pain and urgency, altered stool characteristics and accelerated intestinal transit. ABSTRACT Background Metabolomic analysis in irritable bowel syndrome (IBS) has identified metabotypes enriched in ...
T. E. Conley, A. Duncan, A. Modasia, A. C. Ford, D. M. Pritchard, F. Hildebrand, F. J. Warren, R. Spiller, C. S. Probert   +8 more
wiley   +1 more source