Results 91 to 100 of about 78,813 (321)

Perceptual-assisted Adversarial Adaptation for Choroid Segmentation in optical coherence tomography [PDF]

open access: yesarXiv, 2019
Accurate choroid segmentation in optical coherence tomography (OCT) image is vital because the choroid thickness is a major quantitative biomarker of many ocular diseases. Deep learning has shown its superiority in the segmentation of the choroid region but subjects to the performance degeneration caused by the domain discrepancies (e.g., noise level ...
arxiv  

Choriocapillaris Flow Signal Impairment in Sorsby Fundus Dystrophy [PDF]

open access: yesarXiv, 2021
Purpose: To quantify choriocapillaris flow alterations in early Sorsby Fundus Dystrophy (SFD) and to investigate the relationship of choriocapillaris flow with the choroidal and outer retinal microstructure. Methods: In this prospective case-control study, 18 eyes of 11 patients with early SFD and 32 eyes of 32 controls without ocular pathology ...
arxiv  

Choroid plexus in developmental and evolutionary perspective

open access: yesFrontiers in Neuroscience, 2014
The blood-cerebrospinal fluid boundary is present at the level of epithelial cells of the choroid plexus. As one of the sources of the cerebrospinal fluid, the choroid plexus plays an important role during brain development and function.
Vladimir eKorzh   +3 more
doaj   +1 more source

Eliminating Shadow Artifacts via Generative Inpainting Networks to Quantify Vascular Changes of the Choroid [PDF]

open access: yesarXiv, 2019
Shadow artifacts from retinal vessels hinder the development of quantitative choroidal biomarkers in Optical Coherence Tomography (OCT), which limits the clinical applications of the choroidal OCT to the measures of layer thickness. In this paper, we present a novel framework that could eliminate the retinal shadows and realize the quantification of ...
arxiv  

Rubeola and Choroiditis [PDF]

open access: yesJournal of the American Medical Association, 1914
To the Editor: —Some years ago a child was brought to me who had suddenly developed partial blindness during an attack of rubeola. Ophthalmoscopic examination revealed choroiditis, which advanced to partial atrophy. This case caused me to investigate, and revealed the fact that but few cases of choroidal atrophy can be found which will not furnish a ...
openaire   +2 more sources

Automatic Segmentation of Choroid Layer in EDI OCT Images Using Graph Theory in Neutrosophic Space [PDF]

open access: yesarXiv, 2018
The choroid is vascular tissue located underneath the retina and supplies oxygen to the outer retina; any damage to this tissue can be a precursor to retinal disease. Choroid is almost invisible in Enhanced Depth Imaging Optical Coherence Tomography (EDI-OCT) images and it is hard for an ophthalmologist to detect this layer manually.
arxiv  

Drug delivery pathways to the central nervous system via the brain glymphatic system circumventing the blood‐brain barrier

open access: yesExploration, EarlyView.
The discovery of the glymphatic system has opened up a pathway for drug delivery to the brain by circumventing the blood‐brain barrier, which can effectively improve drug utilization. The methods of drug delivery through the glymphatic system include intrathecal injection, intranasal injection, and delivery through the meningeal lymphatic vessels.
Xiang Wang   +7 more
wiley   +1 more source

Engineered Exosome‐Based Senolytic Therapy Alleviates Stroke by Targeting p21+CD86+ Microglia

open access: yesExploration, EarlyView.
We identified a harmful immune cell type, p21+CD86+ microglia, driving post‐stroke inflammation and developed a targeted exosome‐based therapy (Que@micro‐Exo) to eliminate these cells. This innovative treatment reduced inflammation, alleviated brain damage, and improved recovery in stroke models, offering a promising strategy for stroke and other ...
Jialei Yang, Shipo Wu, Miao He
wiley   +1 more source

Sustained and rebound effect of repeated low‐level red‐light therapy on myopia control: A 2‐year post‐trial follow‐up study

open access: yesClinical &Experimental Ophthalmology, Volume 50, Issue 9, Page 1013-1024, December 2022., 2022
Abstract Background To evaluate the long‐term efficacy and safety of continued repeated low‐level red‐light (RLRL) therapy on myopia control over 2 years, and the potential rebound effect after treatment cessation. Methods The Chinese myopic children who originally completed the one‐year randomised controlled trial were enrolled.
Ruilin Xiong   +13 more
wiley   +1 more source

Choroid plexus volume enlargement in first-episode antipsychotic-naïve schizophrenia

open access: yesSchizophrenia
Investigation of the choroid plexus in schizophrenia has seen growing interest due to its role in the interaction between neuroinflammation and brain dysfunction. Most previous studies included treated and long-term ill patients, while antipsychotics and
Jiaxin Zeng   +12 more
doaj   +1 more source

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