Results 101 to 110 of about 167,748 (392)

Urothelial bladder carcinoma metastasizing to the eye: a systematic review and case report [PDF]

open access: yes, 2019
The eye is a rare site for disseminated malignancies; nevertheless, several tumors may metastasize to ocular structures. Few cases of urothelial and bladder cancer with eye involvement have been described in the literature thus far.
Brunelli, Matteo   +12 more
core   +1 more source

Role of the Choroid in Age-related Macular Degeneration: A Current Review

open access: yesJournal of Ophthalmic & Vision Research, 2019
Age-related macular degeneration (AMD) is a major cause of vision loss in the developed world and its pathogenesis is a topic of active research. To date, much study has been focused on the role of the retinal pigment epithelium (RPE) and Bruch's ...
Marybeth K. Farazdaghi, K. Ebrahimi
semanticscholar   +1 more source

CRISPRa Lipid Nanocomplex‐Mediated Mt3 Targeting Enhances Astrocytic Endocytosis of Amyloid‐β in an Alzheimer's Disease Mouse Model

open access: yesAdvanced Science, EarlyView.
GeTe exhibits intrinsically high carrier concentrations that limit its thermoelectric performance. Herein, CuAgSe alloying synergistically tunes the band structure, induces band flattening and valence‐band convergence, promotes Cu‐ion delocalization, and generates multiscale hierarchical structures to suppress phonon transport.
Junhang Park   +13 more
wiley   +1 more source

A Closer Look at the Global Management of Spina Bifida: The Implementation of Endoscopic Third Ventriculostomy in the Treatment of Spina Bifida-Related Hydrocephalus in Africa [PDF]

open access: yes, 2018
Spina bifida, specifically myelomeningocele, is a debilitating neural tube defect that affects patients and families throughout the world. Traditional management and treatment methods are described, followed by an explanation of why this is often ...
Burckart, Caryssa
core   +1 more source

Choroidal Neovascularization

open access: yesOphthalmology, 1986
Choroidal neovascularization is now considered to be a most important feature in the pathogenesis and treatment of a number of chorioretinal disorders. Since the recognition of its importance, choroidal neovascularization has been described in clinical and pathologic studies of a variety of different ophthalmologic conditions.
W R, Green, D J, Wilson
openaire   +2 more sources

Delayed clearance of cerebrospinal fluid tracer from choroid plexus in idiopathic normal pressure hydrocephalus

open access: yesJournal of Cerebral Blood Flow and Metabolism, 2019
Impaired clearance of amyloid-β from choroid plexus is one proposed mechanism behind amyloid deposition in Alzheimer's disease. The present study examined whether clearance from choroid plexus of a cerebrospinal fluid tracer, serving as a surrogate ...
P. Eide   +4 more
semanticscholar   +1 more source

Elevated Apolipoprotein E Expression in Hippocampal Microglia Drives Temporal Lobe Epilepsy Progression

open access: yesAdvanced Science, EarlyView.
In temporal lobe epilepsy, hippocampal APOE is markedly upregulated predominantly in microglia. APOE overexpression in microglia drives TLR4 and cGAS/STING‐dependent neuroinflammation, engages bidirectional crosstalk with neurons and astrocytes, increases neuronal excitability, and perturbs hippocampal lipid metabolism. These findings suggest that APOE‐
Jianwei Shi   +10 more
wiley   +1 more source

Focal Spot, Summer 1999 [PDF]

open access: yes, 1999
https://digitalcommons.wustl.edu/focal_spot_archives/1082/thumbnail ...

core   +1 more source

Intraocular Metastases Secondary to Breast Carcinoma Correlates With Upregulation of Estrogen and Progesterone Receptor Expression in the Primary Tumor [PDF]

open access: yes, 2016
To compare estrogen (ER), progesterone (PR), and human epidermal growth factor-2 (HER2) receptor expression in the primary tumor of patients affected by choroidal metastases from breast carcinoma (BC) versus those with extraocular ...
Frizziero, Luisa   +7 more
core   +1 more source

Tertiary lymphoid structures in the choroid plexus in neuropsychiatric lupus.

open access: yesJCI Insight, 2019
The central nervous system manifestations of systemic lupus erythematosus (SLE) remain poorly understood. Given the well-defined role of autoantibodies in other lupus manifestations, extensive work has gone into the identification of neuropathic ...
Ariel D. Stock   +6 more
semanticscholar   +1 more source

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