Results 171 to 180 of about 78,813 (321)

Choroidal thickness in primary angle-closure glaucoma: the results of Measurement by Means of Optical Coherence Tomography

open access: yesOftalʹmologiâ, 2014
Purpose: to compare сhoroidal thickness (CT) in primary angle-closure glaucoma (PACG) and primary open angle glaucoma (POAG).Methods: сhoroidal thickness was evaluated in 30 patients (30 eyes) with PACG, 30 patients (30 eyes) with POAG and 30 control ...
N. I. Kurysheva   +2 more
doaj  

Sterol imbalances and cholesterol‐24‐hydroxylase dysregulation is linked to the underlying progression of multiple sclerosis

open access: yesBrain Pathology, EarlyView.
We have sought to determine the role that cholesterol metabolism plays in disability worsening and its correlation with progressive MS by analysing patient CSF and post‐mortem tissues using cutting edge mass spectrometry approaches. Key sterol metabolites measured in the CSF link with important disability milestones at the very early stages of MS ...
Lauren Griffiths   +13 more
wiley   +1 more source

Tubercles of the Choroid [PDF]

open access: yesArchives of Disease in Childhood, 1956
R. S. Illingworth, J. Lorber
openaire   +3 more sources

ERNEST COST action overview on the (patho)physiology of GPCRs and orphan GPCRs in the nervous system

open access: yesBritish Journal of Pharmacology, EarlyView.
G protein‐coupled receptors (GPCRs) are a large family of cell surface receptors that play a critical role in nervous system function by transmitting signals between cells and their environment. They are involved in many, if not all, nervous system processes, and their dysfunction has been linked to various neurological disorders representing important
Necla Birgül Iyison   +15 more
wiley   +1 more source

Blockade of P2X7 receptors preserves blood retinal barrier integrity by modulating the plasmalemma vesicle‐associated protein: Implications for diabetic retinopathy

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Plasmalemma vesicle‐associated protein (PLVAP) regulates transcytosis in vascular endothelial cells. PLVAP expression is increased in pathological conditions, such as diabetic retinopathy. P2X7 receptor antagonists have been shown to preserve blood‐retinal barrier (BRB) integrity.
Chiara Bianca Maria Platania   +16 more
wiley   +1 more source

The glutathione-dependent neuroprotective activity of the blood-CSF barrier is inducible through the Nrf2 signaling pathway during postnatal development. [PDF]

open access: yesFluids Barriers CNS
Strazielle N   +8 more
europepmc   +1 more source

Opportunities to Modulate Tumor Ecosystem Toward Successful Glioblastoma Immunotherapy

open access: yesCancer Science, EarlyView.
There remain outstanding gaps between the negative results from clinical trials and the actual potential of the immune system for glioblastoma. To bridge this crucial gap, we collaborated with Dr. Mariko Takahashi, an expert in immunobiology and drug development, and Dr. James J.
Mariko Takahashi   +5 more
wiley   +1 more source

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