Results 261 to 270 of about 165,368 (343)

Exploring the mechanisms of mutual influence between lactylation and macrophage polarization in the context of disease

open access: yesClinical and Translational Medicine, Volume 15, Issue 11, November 2025.
The conversion of lactate to lactyl‐CoA facilitates enzymatic histone lactylation, transforming glycolytic by‐products into an epigenetic regulatory mechanism for gene expression. Lactylation modification influences macrophage polarization towards M1 or M2 phenotypes, affecting outcomes in infection, cancer and fibrosis. Targeting lactylation modifiers
Houhua Guo   +5 more
wiley   +1 more source

Perivascular Space Burden in Children With Autism Spectrum Disorder Correlates With Neurodevelopmental Severity

open access: yesJournal of Magnetic Resonance Imaging, Volume 62, Issue 5, Page 1496-1506, November 2025.
ABSTRACT Background Cerebral perivascular spaces (PVS) are involved in cerebrospinal fluid (CSF) circulation and clearance of metabolic waste in adult humans. A high number of PVS has been reported in autism spectrum disorder (ASD) but its relationship with CSF and disease severity is unclear.
Giulia Frigerio   +8 more
wiley   +1 more source

Axial Length Profiles in Inherited Retinal Diseases-A Genotypic and Phenotypic Analysis. [PDF]

open access: yesInvest Ophthalmol Vis Sci
Zhang L   +8 more
europepmc   +1 more source

Expression of cytokines in porcine iris, retina and choroid tissues stimulated by microbe-associated molecular patterns

open access: green, 2018
Yong Seop Han   +7 more
openalex   +1 more source

Cystoid macular edema in gyrate atrophy of choroid and retina associated with hyperornithinemia

open access: diamond, 2019
Martina Galiot Delić   +5 more
openalex   +2 more sources

Retinal Pigment Epithelium‐Targeting Gene Therapy Corrects Ocular Symptoms in Mouse and Rat Models of Oculocutaneous Albinism Type I

open access: yesMedComm, Volume 6, Issue 11, November 2025.
RPE‐targeted gene therapy restored melanin expression and relieved ocular dysfunction. By optimizing the injection method, a wider range of melanin expression and better therapeutic effects have been achieved. ABSTRACT Oculocutaneous albinism (OCA) represents a genetically heterogeneous autosomal recessive condition marked by reduced melanin production
Li Song   +18 more
wiley   +1 more source

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