Results 31 to 40 of about 79,402 (255)

ube3d, a New Gene Associated with Age-Related Macular Degeneration, Induces Functional Changes in Both In Vivo and In Vitro Studies

open access: yesMolecular Therapy: Nucleic Acids, 2020
Neovascular age-related macular degeneration (AMD) is characterized by the formation of choroidal neovascularization, which is responsible for more than 80% of cases of severe vision loss.
Huika Xia   +15 more
doaj   +1 more source

Choroidal schwannoma [PDF]

open access: yesActa Ophthalmologica Scandinavica, 2005
Abstract.Purpose:  Schwannoma is rarely encountered as an intraocular tumor arising from uveal tract. We describe a case of choroidal schwannoma. Methods:  A 74‐year‐old woman presented with rapidly decreasing visual acuity and proptosis for 2 months. To further delineate the tumor, she underwent enucleation of the eyeball.
Sang-Hyeok, Lee   +3 more
openaire   +2 more sources

Short-Term Results of Switch from Conbercept to Bevacizumab or Ranibizumab in Eyes with Persistent Neovascular Age-Related Macular Degeneration

open access: yesJournal of Ophthalmology, 2020
Purpose. To study the short-term anatomical and functional outcomes in patients with neovascular age-related macular degeneration (nAMD) who were previously treated with conbercept and switched to ranibizumab or bevacizumab due to persistent activity ...
Zongyi Wang   +7 more
doaj   +1 more source

Focal Choroidal Excavation in a Case of Choroidal Osteoma Associated with Choroidal Neovascularization

open access: yesJournal of Ophthalmic and Vision Research, 2020
Purpose: To report a case of choroidal osteoma associated with reactivation of choroidal neovascularization (CNV) and development of focal choroidal excavation (FCE). Case Report: A 34-year-old woman with choroidal osteoma complicated by CNV in the right eye for two years presented with deterioration of visual acuity in her right eye.
Mahdieh Azimizadeh   +2 more
openaire   +4 more sources

Unmasking of molecular players: proteomic profiling of vitreous humor in pathologic myopia

open access: yesBMC Ophthalmology
Background This study aimed to identify the differentially expressed proteins in the vitreous humor (VH) of eyes with and without pathologic myopia (PM), providing insights into the molecular pathogenesis.
Yue Wen   +8 more
doaj   +1 more source

Effect of Exogenous Alpha-B Crystallin on the Structures and Functions of Trabecular Meshwork Cells

open access: yesJournal of Ophthalmology, 2018
Purpose. Secondary open-angle glaucoma may develop as a postoperative complication of early childhood cataract surgery. Its mechanism is poorly understood.
Hui Xu, Li Zhu, Yu Wang, Yongzhen Bao
doaj   +1 more source

TUBERCULOSIS OF THE CHOROID. [PDF]

open access: yesThe Lancet, 1901
n ...
Carpenter, George, Stephenson, Sydney
openaire   +2 more sources

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Small Interfering RNA Targeted to ASPP2 Promotes Progression of Experimental Proliferative Vitreoretinopathy

open access: yesMediators of Inflammation, 2016
Background. Epithelial-mesenchymal transition (EMT) of retinal pigment epithelium (RPE) is vital in proliferative vitreoretinopathy (PVR) development.
Xiao-Li Chen   +5 more
doaj   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

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