Results 51 to 60 of about 79,402 (255)

The analysis of foveal microvascular anomalies in retinopathy of prematurity after anti-vascular endothelial growth factor therapy using optical coherence tomography angiography

open access: yesBMC Ophthalmology
Background To investigate the quantitative vascular and structural differences in the foveal region of the eyes in retinopathy of prematurity children with or without anti-vascular endothelial growth factor (VEGF) therapy and healthy children using ...
Wenbo Liu   +10 more
doaj   +1 more source

Comparative Analysis of Choroid Plexus Volume Between MOG Antibody Associated Disease and Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Choroid plexus volume (CPV) has been proposed as a neuro‐immunological marker of multiple sclerosis (MS), but its relevance in myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD) remains uncertain. We analyzed CPV in 43 individuals with MOGAD, 48 with MS, and 44 healthy controls using a Bayesian Gaussian mixture modeling ...
Jae‐Won Hyun   +4 more
wiley   +1 more source

Targeting choroid plexus epithelium as a novel therapeutic strategy for hydrocephalus

open access: yesJournal of Neuroinflammation, 2022
The choroid plexus is a tissue located in the lateral ventricles of the brain and is composed mainly of choroid plexus epithelium cells. The main function is currently thought to be the secretion of cerebrospinal fluid and the regulation of its pH, and ...
Yijian Yang   +7 more
doaj   +1 more source

Engineering Concentration‐Dependent Intravitreal Mobility via Cyclic Arginine‐Enriched Nanocarrier Surface Modification: In Vivo Proof‐of‐Concept in a Porcine Large Animal Model

open access: yesAdvanced Healthcare Materials, EarlyView.
In this study, Hammer et al. highlight cyclic‐arginine surface engineering as a highly biocompatible, controllable, and concentration‐dependent regulator of intravitreal nanoparticle mobility in vivo in a translational large animal model. The cyclic arginine surface‐modification supports the development of next‐generation biomaterials for long‐acting ...
Maximilian Hammer   +12 more
wiley   +1 more source

Comparative morphological analysis of the zonular apparatus in porcine, feline, and canine species

open access: yesFrontiers in Medicine
PurposeTo characterize and compare the morphology of the zonular apparatus in pigs, cats, and dogs to identify the optimal animal model for studying zonular pathophysiology in angle-closure mechanisms.MethodsPorcine (n = 15), feline (n = 8), and canine ...
Ye Lu   +15 more
doaj   +1 more source

From Rigid to Soft Robotic Approaches for Neuroendoscopy

open access: yesAdvanced Robotics Research, EarlyView.
Robotic assistance has had minimal impact on deep intraventricular surgeries, where small‐scale, precision, and reduced invasiveness can contribute to improved patient outcomes. Emerging technologies in rigid, soft, and hybrid robotics are reviewed to identify the most promising mechanisms for deep brain navigation in addition to an attempt to identify
Kieran Gilday   +3 more
wiley   +1 more source

An extremely rare case of choroid plexus carcinoma in the third ventricle of an infant – Case report and review of the literature

open access: yesInterdisciplinary Neurosurgery, 2020
Background: Choroid plexus tumors are rare intraventricular tumors. Most of these tumors are benign choroid plexus papillomas. Choroid plexus carcinoma is the most malignant choroid plexus tumor and constitutes a small percentage of these tumors.
Amin Tavallaii   +3 more
doaj   +1 more source

A Whole‐Head Finite Element Model for Electrical Neuromodulation via Visual Brain‐Machine Interfaces

open access: yesAdvanced Science, EarlyView.
A multimodal, personalized head model is presented that integrates the entire visual pathway with surrounding tissues to simulate electrical stimulation of the optic nerve. In vivo validation in humans and goats, plus systematic component‐elimination analysis, demonstrates the high accuracy of the comprehensive model.
Shengjian Lu   +12 more
wiley   +1 more source

Beyond the Fixed Charge: A New On‐Tissue Derivatisation Strategy Employing Photoionisable Chromophores for Mass Spectrometry Imaging of Amino‐Containing Metabolites

open access: yesAngewandte Chemie, EarlyView.
We introduce a novel chemical derivatisation strategy for the UV‐activated detection of elusive metabolites. Incorporation of a tocopherol‐active chromophore allows for the detection of tagged analytes as photoionised radical cations, selectively induced by a 266 nm laser.
Sofia R. McGowan   +5 more
wiley   +2 more sources

NeuroSuite for Long‐Term Functional and Structural Studies of Air‐Liquid Interface Cerebral Organoids

open access: yesAdvanced Science, EarlyView.
NeuroSuite provides a modular hardware‐software platform integrating Neuroweb and NeuroMaps to enable long‐term, in situ electrophysiological interrogation of air–liquid interface organoid slices while preserving tissue architecture. Its components can be used together or independently to capture real‐time activity, spatial network dynamics, and ...
Belquis Haider   +14 more
wiley   +1 more source

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