Results 51 to 60 of about 91,251 (315)

OTX2 Homeoprotein Functions in Adult Choroid Plexus

, 2021
International audienceThe choroid plexus is an important blood barrier that secretes cerebrospinal fluid, which essential for embryonic brain development and adult brain homeostasis.
Florent Dingli, Oliveira Moreira, Vanessa, David Benacom, Corinne Blugeon, Dingli, Florent, Vanessa Masson, Jourdren, Laurent, Anabelle Planques, Di Nardo, Ariel, A, Planques, Anabelle, Ariel A. Di Nardo, Bernard, Clémence, Masson, Vanessa, Clémence Bernard, Prochiantz, Alain, Benacom, David, Blugeon, Corinne, Loew, Damarys, Vanessa Oliveira Moreira, Damarys Loew, Alain Prochiantz, Laurent Jourdren   +21 more
core   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

Associations of prenatally detected choroid plexus cysts with biochemical risk for congenital disorders

, 2014
Introduction: C horoid plexus cysts are one of the foetus ultrasonography findings that raise parents’ concerns about their child’s health. Usually cysts are found in an estimated 1% all performed ultrasonographies.
Marius Sukys, Povilas Bardziliauskas, Danielius Serapinas   +2 more
core   +1 more source

Direct observation and measurement of circumlental space and its relation to anterior chamber angle characteristics in iridotomized phakic eyes with primary angle closure disease

Scientific Reports
Primary angle closure disease (PACD) is a major cause of blindness worldwide. It has a high prevalence in East Asia, especially in China, which leads to a higher incidence of blindness than open-angle glaucoma.
Zhiqiao Liang, Kangyi Yang, Kun Lv, Yao Ma, Xuanzhu Chen, Zeqin Ren, Yong Liang, Xianru Hou, Huijuan Wu   +8 more
doaj   +1 more source

Comparative morphological analysis of the zonular apparatus in porcine, feline, and canine species

Frontiers in Medicine
PurposeTo characterize and compare the morphology of the zonular apparatus in pigs, cats, and dogs to identify the optimal animal model for studying zonular pathophysiology in angle-closure mechanisms.MethodsPorcine (n = 15), feline (n = 8), and canine ...
Ye Lu, Ye Lu, Kuankuan Wu, Kuankuan Wu, Zhiqiao Liang, Zhiqiao Liang, Kun Lv, Kun Lv, Zeyuan Wang, Zeyuan Wang, Fengrui Yang, Fengrui Yang, Yitong Hu, Yitong Hu, Huijuan Wu, Huijuan Wu   +15 more
doaj   +1 more source

The multifunctional choroid [PDF]

Progress in Retinal and Eye Research, 2010
The choroid of the eye is primarily a vascular structure supplying the outer retina. It has several unusual features: It contains large membrane-lined lacunae, which, at least in birds, function as part of the lymphatic drainage of the eye and which can change their volume dramatically, thereby changing the thickness of the choroid as much as four-fold
Debora L, Nickla, Josh, Wallman
openaire   +2 more sources

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Choroid plexus tumours

, 2017
Choroid plexus tumours are rare, intraventricular, primary central nervous system tumours derived from the choroid plexus epithelium. They occur predominantly in children and are classified based on histological criteria as choroid plexus papilloma ...
Maria Santos, Eric Bouffet, Carolyn Freeman, Mark M. Souweidane   +3 more
core   +1 more source

Diurnal changes of retinal microvascular circulation and RNFL thickness measured by optical coherence tomography angiography in patients with obstructive sleep apnea–hypopnea

Frontiers in Endocrinology, 2022
PurposeTo evaluate capillaries perfusion and retinal nerve fiber layer (RNFL) thickness diurnal changes of macular/optic disc regions among participants with or without obstructive sleep apnea-hypopnea (OSA) using spectral-domain optical coherence ...
Yi Cai, Wen-Bo Liu, Miao Zhou, Yu-Tong Jin, Guo-Sheng Sun, Long Zhao, Fang Han, Jin-Feng Qu, Xuan Shi, Ming-Wei Zhao   +9 more
doaj   +1 more source

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao, Rong Li, Yu‐Xiang Jiao, Kai Ma, Hong‐Qi Yang, Zheng‐Yu Sun, Jie‐Wen Zhang, Shuai Chen   +7 more
wiley   +1 more source