Results 181 to 190 of about 2,322,168 (296)

Multimodal Characterization of Glymphatic‐Related Magnetic Resonance Imaging Markers in Huntington's Disease: A Multi‐Cohort Retrospective Study

Annals of Neurology, Volume 100, Issue 5, Page 1055-1067, November 2026.
Objective To characterize magnetic resonance imaging (MRI)‐based glymphatic surrogates in Huntington's disease (HD) using MRI measures of perivascular diffusivity and structural perivascular alterations across multiple large cohorts. Methods We analyzed 2,731 MRI sessions from 880 participants across 3 large retrospective HD cohorts.
Alexia Solomon, Zexi Wang, Francesco Sanvito, Zheng Zhou, Adys Mendizabal, Jingwen Yao   +5 more
wiley   +1 more source

Integrating brain organoids, meningeal immunity, and glymphatic dynamics: toward modeling neuroimmune clearance and crosstalk in disease. [PDF]

Front Immunol
Wu X, Du B, Chen Q, Hang R, Cui C, Li M.
europepmc   +1 more source

Monitoring pharmacodynamic and molecular drug targets in liquid biopsy: Exploratory study in liver cancer with modelling of EGFR Receptor engagement

British Journal of Clinical Pharmacology, Volume 92, Issue 11, Page 3902-3913, November 2026.
Abstract Aim Liquid biopsy is minimally invasive (compared with tissue biopsy) and has previously been used to generate systems data regarding drug elimination via hepatic enzymes and transporters. This study extends quantitative assessment of systems parameters in liquid biopsy to pharmacodynamic (PD) and disease markers relevant to cancer development
Zubida M. Al‐Majdoub, Armin Sepp, Amin Rostami‐Hodjegan, Brahim Achour   +3 more
wiley   +1 more source

Cerebrospinal Fluid as a Window into Neuroimmune Responses During Brain Infection. [PDF]

Cells
Singh G, Rohlwink UK.
europepmc   +1 more source

Single-cell analysis of the epigenome and 3D chromatin architecture in the human retina. [PDF]

Sci Adv
Yuan Y, Biswas P, Zemke NR, Dang K, Wu Y, D'Antonio M, Xie Y, Yang Q, Dong K, Lau PK, Li D, Seng C, Bartosik W, Buchanan J, Lin L, Lancione R, Wang K, Lee S, Gibbs Z, Yang B, Ecker JR, Frazer K, Wang T, Preissl S, Wang A, Ayyagari R, Ren B.   +26 more
europepmc   +1 more source

Oxytocin Affects Barriergenesis in the Blood-Brain Barrier and the Blood-Cerebrospinal Fluid Barrier In Vitro Monoculture Transwell Models. [PDF]

Dev Neurobiol
Averchuk AS, Aleksandrova OP, Zhdankina VI, Perepelitsa ES, Berdnikov AK, Salina KО, Yurchenko SО, Salmina AB.   +7 more
europepmc   +1 more source

Investigating Risk Factors for Delayed Melanoma Recurrence Beyond 5 Years Post‐Primary Tumor Diagnosis

Cancer Medicine, Volume 15, Issue 11, November 2026.
ABSTRACT Background Patients undergoing treatment for cutaneous melanoma are generally considered cured after a period of 5 years, since most recurrences manifest within three to 5 years. However, some patients can present with a delayed recurrence of melanoma beyond a 10‐year timeframe.
Kaspar Itin, Rebecca Lapides, Soumya Paria, Babak Saravi, Alina. M. Torrez, Lara Valeska Maul, Michael Wang‐Evers, Alexander A. Navarini, Dieter Manstein, Beata Kun, Leticia Szadai, Judit Olàh, Eszter Baltas, Rolland Gyulai, Peter Hollo, Grzegorz Sarek, Istvan B. Németh, Kaustubh Adhikari, Elisabeth Roider   +18 more
wiley   +1 more source

AAV-NRF2 protects retinal and choroidal vasculature in a GDF15-dependent manner in an oxidative damage model of AMD. [PDF]

Proc Natl Acad Sci U S A
Wang S, Zhao S, Daniels A, Naaman E, Gardner A, Smith LEH, Cepko CL.   +6 more
europepmc   +1 more source

Prenatal Diagnosis of Recurrent Fetal Intracranial Hemorrhage and a Maternally Inherited COL4A1 Variant of Uncertain Significance: A Case Report With Maternal Reverse Phenotyping

Clinical Case Reports, Volume 14, Issue 11, November 2026.
ABSTRACT A 33‐year‐old woman with two consecutive pregnancies affected by fetal left periventricular germinal matrix hemorrhage (Grade IV) and progressive ventriculomegaly underwent trio whole‐exome sequencing. A heterozygous COL4A1 c.4249G>C (p.Gly1417Arg) variant, classified as a variant of uncertain significance, was identified in the fetus of the ...
Wei Shi, Hongjing Xu, Caihong Pu, Yuanzhong Liang, Ting Zhao, Xueli Wang, Zhenxing Liu, Chunhua Zhang, Ting Li, Fengquan He   +9 more
wiley   +1 more source

Aging-Related Choroidal Heterogeneity and Loss: An Investigative Global Human Choroidal Thickness Review (ARCHLIGHT Study). [PDF]

J Vitreoretin Dis
Lai A, Issa M, Ali A, Pereira A, Ali AA, Chhablani J, Yan P.   +6 more
europepmc   +1 more source