Results 171 to 180 of about 2,322,168 (296)

Hypothalamic Neurochemical and Microglial Suppression in Long‐Standing Human Hibernation‐Like Syndrome

Neuropathology and Applied Neurobiology, Volume 52, Issue 6, December 2026.
A rare case of a human hibernation‐like syndrome was associated with preserved hypothalamic anatomy but profound suppression of neuroendocrine and circadian neuropeptide systems. Marked reductions in synaptic and microglial immunoreactivity suggest a suppressed hypothalamic neuron–glial network, despite preserved astrocytic markers, myelination and ...
Wei Jiang, Andries Kalsbeek, Roelof A. Hut, Dick F. Swaab, Chun‐Xia Yi   +4 more
wiley   +1 more source

A Possible Link Between Cutaneous Melanoma and Uveal Melanoma: A Multicenter Retrospective Cohort Study. [PDF]

Cancers (Basel)
Eiger-Moscovich M, Lishinsky-Fischer N, Frenkel S, Pe'er J, Moscovich A, Gur Z.   +5 more
europepmc   +1 more source

Copy‐Number Alterations in Central Nervous System Tumours: Diagnostic and Prognostic Implications

Neuropathology and Applied Neurobiology, Volume 52, Issue 6, December 2026.
This review summarises recurrent copy‐number alterations across the spectrum of CNS tumours, classifies them into diagnostic, prognostic and supportive categories, and highlights how characteristic CNA combinations support tumour classification, grading and risk stratification in neuropathological diagnostics.
Christian Thomas
wiley   +1 more source

Innovative PLA or PCL‐Based Ocular Implants Obtained From Tape Casting or Electrospinning for Sustained‐Release Dexamethasone

Journal of Applied Polymer Science, Volume 143, Issue 43, November 15, 2026.
PLA and PCL ocular implants prepared by tape casting and electrospinning provide sustained dexamethasone release with distinct release profiles governed by polymer type and processing method. The relationship between polymer structure, degradation behavior, and drug release demonstrates the potential of these fabrication techniques for controlled ...
Renata Bochanoski, Henrique Borba Modolon, Ronaldo Silveira, Januara Rodrigues, Tiago Bender Wermuth, Sabrina Arcaro, Oscar R. K. Montedo   +6 more
wiley   +1 more source

Choroid plexus volume in metabolic syndrome: a cross-sectional neuroimaging study. [PDF]

Front Neurol
Huo X, Chen T, Cheng Z, Chen B, Zhang F, Chen Y, Liang P, Zhang N, Che Y, Liang C, Guo L, Li M.   +11 more
europepmc   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, Volume 600, Issue 21, Page 3137-3150, November 2026.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Region-Specific Proteomic Profiles of Extracellular Vesicles (EVs) Derived from Human Macular and Peripheral RPE-Choroid Explants. [PDF]

Biomedicines
Zeng J, Zhang J, Schulz J, Arafah ADB, Lee S, Yam M, Shen Y, Zhou F, Zhang T, Gillies MC, Zhu L.   +10 more
europepmc   +1 more source

Engineered Brain‐Targeted Exosomes Delivering FGF1 for Sustained Glycemic Regulation and Multitarget Neurovascular Protection in Diabetic Stroke

Advanced Science, Volume 13, Issue 61, 3 November 2026.
ABSTRACT Diabetic stroke is characterized by a hyperglycemic and pro‐inflammatory microenvironment that exacerbates neurovascular dysfunction. However, the blood–brain barrier (BBB) remains a formidable obstacle, restricting the delivery of most therapeutic molecules.
Bixin Shen, Chengxiang Zhang, Junhui Wang, Xichong Zhong, Shihao Chen, Xue Wang, Xiaokun Li, Li Lin   +7 more
wiley   +1 more source

A clear view at altitude: layer-specific control of the choroidal circulation. [PDF]

Function (Oxf)
Fan JL, Turnbull PRK.
europepmc   +1 more source

Age‐Dependent Prognostic Significance of Preoperative Transthyretin After Curative Resection for Stage I–III Colorectal Cancer

Annals of Gastroenterological Surgery, Volume 10, Issue 6, Page 1770-1779, November 2026.
ABSTRACT Background Preoperative malnutrition and systemic inflammation are established determinants of adverse outcomes in colorectal cancer (CRC). Transthyretin (TTR), a rapid‐turnover hepatic protein, reflects both nutritional and inflammatory status; however, its clinical utility may be influenced by age‐ and sex‐related variability.
Ayane Kawata, Yuji Miyamoto, Hiro Nakamura, Takahiko Akiyama, Kota Arima, Katsuhiro Ogawa, Yukiharu Hiyoshi, Masaaki Iwatsuki   +7 more
wiley   +1 more source