Ergothioneine as a potential protective agent against macular degeneration and other eye disorders. [PDF]
Cheah IK +12 more
europepmc +1 more source
In this report, we present the results of a nationwide initiative launched by the Japan Children's Cancer Group to provide integrated diagnoses for pediatric central nervous system (CNS) tumors, incorporating central pathological review and molecular profiling.
Yoshiko Nakano +39 more
wiley +1 more source
Differential regulation of myopia progression by ON and OFF stimulation in guinea pigs. [PDF]
Xie Q +9 more
europepmc +1 more source
An update on the landscape of collagen bioactive fragments
The remodeling of the extracellular matrix releases collagen bioactive fragments, which exert molecular functions and regulate numerous biological processes via several signaling pathways. Here, we summarize the latest findings describing the roles of major bioactive fragments from collagens I, IV, VI, and XVIII in various physiological and ...
Sylvie Ricard‐Blum, Julie Fradette
wiley +1 more source
Relationship between choroidal thickness changes and macrophage polarization in high myopia. [PDF]
Zhou Z, Long W, Zheng B, Cui D.
europepmc +1 more source
Variability in intracellular localization of D‐amino acid oxidase in choroid plexus epithelial cells
D‐amino acid oxidase (DAO) in choroid plexus epithelial cells (CPECs) shows vesicle‐like localization by histological and super‐resolution analyses. DAO colocalizes with peroxisomal, Golgi, endosomal, lysosomal, autophagosomal, and exosomal markers, indicating diverse subcellular distribution. This suggests DAO is transported within CPECs to metabolize
Koji Ono +3 more
wiley +1 more source
Spatial Selective Choroidal Stromal and Vascular Changes in Intermediate AMD: Insights From High-Density Optical Coherence Tomography Analysis. [PDF]
Kumar M +3 more
europepmc +1 more source
Proteolytic remodelling of the extracellular matrix by pericytes
Pericytes are specialised perivascular cells intimately connected with endothelial cells and essential for the maintenance of vascular beds. They contribute to the formation and remodelling of the extracellular matrix by actively secreting proteases and protease inhibitors.
Tina Burkhard +4 more
wiley +1 more source
Association between choroidal thickness and primary open angle glaucoma in highly myopic eyes. [PDF]
Jin PY +8 more
europepmc +1 more source
RNA‐based CLEM (RCLEM) bridging RNA localisation and ultrastructural mapping in 3D
Abstract Spatial transcriptomics and in situ hybridisation techniques have become essential for contextualising single‐cell RNA sequencing (scRNA‐seq) data by mapping cell type– and state–specific mRNA expression within intact tissues. Beyond validating scRNA‐seq predictions, these spatial methods provide critical insight into the localisation of ...
Daan Verhaege +8 more
wiley +1 more source

