Results 171 to 180 of about 2,173,247 (301)

Outcomes of adult patients with Li‐Fraumeni syndrome and myeloid neoplasms

open access: yesCancer, Volume 132, Issue 19, 1 October 2026.
Abstract Background Li‐Fraumeni syndrome (LFS) is an inherited cancer predisposition syndrome. Hematologic malignancies are not considered LFS defining tumors, however, both acute lymphoblastic leukemia and therapy‐related myeloid neoplasms (MNs) in LFS are described. Treatment approaches and outcomes of MN in LFS need further evaluation.
Jayastu Senapati   +19 more
wiley   +1 more source

Oxytocin Affects Barriergenesis in the Blood-Brain Barrier and the Blood-Cerebrospinal Fluid Barrier In Vitro Monoculture Transwell Models. [PDF]

open access: yesDev Neurobiol
Averchuk AS   +7 more
europepmc   +1 more source

Short‐Chain Fatty Acids: Microbial Metabolites Driving Gut‐Eye Axis Signaling

open access: yesComprehensive Physiology, Volume 16, Issue 5, October 2026.
Short‐chain fatty acids generated by gut microbial fermentation link diet to ocular physiology via the gut–eye axis. Through systemic distribution, these metabolites regulate GPCR signaling, epigenetic pathways, inflammation, and angiogenesis, shaping retinal homeostasis and highlighting therapeutic potential in ocular vascular and inflammatory ...
Aleah J. Brokemond   +6 more
wiley   +1 more source

AAV-NRF2 protects retinal and choroidal vasculature in a GDF15-dependent manner in an oxidative damage model of AMD. [PDF]

open access: yesProc Natl Acad Sci U S A
Wang S   +6 more
europepmc   +1 more source

Report of the Advisory Committee on Communicable Diseases in Prison.

open access: yes, 1993
In 1990 the Minister for Justice announced the establishment of an Advisory Committee on Communicable Diseases in Prisons with the following terms of reference:- "To examine the problems posed by communicable diseases affecting offenders in prisons ...
Advisory Committee on Communicable Diseases in Prison
core  

DTI‐ALPS as a Biomarker of Small Vessel Disease Progression and Amyloid‐β in Normal Aging: A 3‐Year Longitudinal Study

open access: yesHuman Brain Mapping, Volume 47, Issue 14, October 1, 2026.
A higher DTI‐derived ALPS index relates cross‐sectionally to both quantitative and visual measures of SVD and is associated with short‐term amyloid‐β accumulation in cognitively normal older adults. Also, greater amyloid burden and choroid plexus volume are associated with a more rapid deterioration in global cognition and processing speed.
Narges Azizi   +6 more
wiley   +1 more source

Beyond the Fixed Charge: A New On‐Tissue Derivatisation Strategy Employing Photoionisable Chromophores for Mass Spectrometry Imaging of Amino‐Containing Metabolites

open access: yesAngewandte Chemie, Volume 138, Issue 37, 7 September 2026.
We introduce a novel chemical derivatisation strategy for the UV‐activated detection of elusive metabolites. Incorporation of a tocopherol‐active chromophore allows for the detection of tagged analytes as photoionised radical cations, selectively induced by a 266 nm laser.
Sofia R. McGowan   +5 more
wiley   +2 more sources

PSEN1 Expression Identifies a Developmentally Distinct Favourable‐Prognosis State in SHH α Medulloblastoma

open access: yesInternational Journal of Developmental Neuroscience, Volume 86, Issue 6, October 2026.
High PSEN1 expression identifies a favourable‐prognosis state in SHH α medulloblastoma and is associated with a reproducible transcriptional programme related to cellular homeostasis and development. Its broad expression during cerebellar development and across paediatric brain tumours suggests that its prognostic significance reflects the specific ...
Julia Vanini   +6 more
wiley   +1 more source

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