ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur +6 more
wiley +1 more source
Laser photocoagulation improves the transduction efficiency of lentivirus vectors injected intravitreally. [PDF]
Jiao J, Xu YJ, Li XD, Hua W, Jiang YR.
europepmc +1 more source
ABSTRACT Background and aims Non‐alcoholic Fatty Liver Disease (NAFLD) affects about a quarter of the world's population. Liver biopsy remains the gold standard for diagnosing the progressive form of NAFLD called Non‐alcoholic Steatohepatitis (NASH) but it is invasive, prone to sampling errors and observer variability, and impractical for widespread ...
Anna Negroni +5 more
wiley +1 more source
Role of BDNF in form-deprivation myopia progression in guinea pigs. [PDF]
Xie RY +7 more
europepmc +1 more source
Sedative effects of intramuscular injection of dexmedetomidine and ketamine or dexmedetomidine and midazolam on tear production (TP), ocular perfusion pressure (OPP) and pupillary diameter (PD) in two groups of seven male New Zealand rabbits (G1 and G2, respectively).
Maryam Mohammadzadeh +2 more
wiley +1 more source
Non-intravitreal anti-vascular endothelial growth factor delivery for ocular neovascular diseases: Current status and future directions. [PDF]
Joshi SM +4 more
europepmc +1 more source
An Algorithm at the Table at Multidisciplinary Diagnostic Meetings: A Dramaturgical Analysis
ABSTRACT This paper focuses on how a radiological classification algorithm temporarily became part of existing diagnostic deliberations between different medical specialists. It describes a participatory ethnographic case study in which the output of the algorithm was presented by the first author during weekly multidisciplinary neuro‐oncology meetings.
Justien Dingelstad +3 more
wiley +1 more source
Choroid plexus cyst of the spinal cord presenting with signs of spinal cord compression in a 55-year-old male: a case report. [PDF]
Alassaf S +8 more
europepmc +1 more source
Humanin Mitigates Aβ‐Induced Retinal Pigment Epithelium Injury via AMPK‐Beclin1‐Dependent Mitophagy
Humanin (HN) enhanced the clearance of Aβ‐accumulated mitochondria in the RPE while preserving retinal function and RPE barrier integrity. HN activated AMP‐activated protein kinase (AMPK), leading to phosphorylation of ULK1 and Beclin1, which promoted the interaction between Beclin1 and Parkin and their translocation to mitochondria.
Ha Young Jang +7 more
wiley +1 more source
Identification of COL4A2 as a Biomarker of Extracellular Matrix Remodeling and Vascular Scaffold in Choroid for Myopia. [PDF]
Chen B +7 more
europepmc +1 more source

