Results 161 to 170 of about 49,505 (301)

Multi‐Targeting Ligands as Prospective Therapeutics for Alzheimer's Disease, a Prevalent Neurodegenerative Disorder: Mechanistic Insights, Emerging Targets and Drug Discovery Campaigns

open access: yesMedicinal Research Reviews, Volume 46, Issue 4, Page 1173-1229, July 2026.
ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur   +6 more
wiley   +1 more source

Fecal Proteomics Suggest Potential Biomarkers for Non‐Alcoholic Fatty Liver Disease and Steatohepatitis

open access: yesPROTEOMICS – Clinical Applications, Volume 20, Issue 4, July 2026.
ABSTRACT Background and aims Non‐alcoholic Fatty Liver Disease (NAFLD) affects about a quarter of the world's population. Liver biopsy remains the gold standard for diagnosing the progressive form of NAFLD called Non‐alcoholic Steatohepatitis (NASH) but it is invasive, prone to sampling errors and observer variability, and impractical for widespread ...
Anna Negroni   +5 more
wiley   +1 more source

Role of BDNF in form-deprivation myopia progression in guinea pigs. [PDF]

open access: yesFront Immunol
Xie RY   +7 more
europepmc   +1 more source

Sedative Effects of Dexmedetomidine and Ketamine or Dexmedetomidine and Midazolam on Tear Production, Ocular Perfusion Pressure and Pupil Diameter in Rabbits

open access: yesVeterinary Medicine and Science, Volume 12, Issue 4, July 2026.
Sedative effects of intramuscular injection of dexmedetomidine and ketamine or dexmedetomidine and midazolam on tear production (TP), ocular perfusion pressure (OPP) and pupillary diameter (PD) in two groups of seven male New Zealand rabbits (G1 and G2, respectively).
Maryam Mohammadzadeh   +2 more
wiley   +1 more source

An Algorithm at the Table at Multidisciplinary Diagnostic Meetings: A Dramaturgical Analysis

open access: yesSociology of Health &Illness, Volume 48, Issue 6, July 2026.
ABSTRACT This paper focuses on how a radiological classification algorithm temporarily became part of existing diagnostic deliberations between different medical specialists. It describes a participatory ethnographic case study in which the output of the algorithm was presented by the first author during weekly multidisciplinary neuro‐oncology meetings.
Justien Dingelstad   +3 more
wiley   +1 more source

Choroid plexus cyst of the spinal cord presenting with signs of spinal cord compression in a 55-year-old male: a case report. [PDF]

open access: yesJ Med Case Rep
Alassaf S   +8 more
europepmc   +1 more source

Humanin Mitigates Aβ‐Induced Retinal Pigment Epithelium Injury via AMPK‐Beclin1‐Dependent Mitophagy

open access: yesAging Cell, Volume 25, Issue 7, July 2026.
Humanin (HN) enhanced the clearance of Aβ‐accumulated mitochondria in the RPE while preserving retinal function and RPE barrier integrity. HN activated AMP‐activated protein kinase (AMPK), leading to phosphorylation of ULK1 and Beclin1, which promoted the interaction between Beclin1 and Parkin and their translocation to mitochondria.
Ha Young Jang   +7 more
wiley   +1 more source

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