Region-Specific Proteomic Profiles of Extracellular Vesicles (EVs) Derived from Human Macular and Peripheral RPE-Choroid Explants. [PDF]
Zeng J +10 more
europepmc +1 more source
Walsh & Hoyt: Choroid Plexus Tumors
During embryogenesis, the cells that line the villi of the choroid plexus are initially similar to those that line the rest of the ventricular system, containing both cilia and blepharoplasts.
Thomas R. Hedges III, MD
core
Glial Dysfunction and Memory Impairments in a Model of Pediatric Obstructive Sleep Apnea
Generation and analysis of an snRNA‐seq atlas of the hippocampus in POSA. Validation of reduced protein expression of six genes across four cell types. Cellular‐level investigation of aberrant glial function in POSA using transgenic reporter mice. ABSTRACT Pediatric obstructive sleep apnea (POSA) is a common childhood disease that often causes aberrant
Michael R. Williamson +13 more
wiley +1 more source
A clear view at altitude: layer-specific control of the choroidal circulation. [PDF]
Fan JL, Turnbull PRK.
europepmc +1 more source
Using Manganese‐Enhanced DCE‐MRI to Assess Blood‐Cerebrospinal Fluid Barrier Transport
ABSTRACT PurposeWe developed a dynamic, heavily T2‐weighted (hT2w) FLAIR protocol to resolve acute Mn2+ transport kinetics, as a proxy for Ca2+, across the choroid plexus (ChP)—cerebrospinal fluid (CSF) interface, in vivo. By quantifying intercompartmental Mn2+ dynamics, and comparing these with Gd‐DOTA, we sought to characterize blood‐CSF‐barrier ...
Charith Perera +9 more
wiley +1 more source
ABSTRACT Background Neurotoxicity is a rare, often dose‐limiting adverse effect of methotrexate (MTX) therapy that disproportionally affects Latino children. Factors contributing to the observed disparity are not well understood. This study leveraged admixture mapping to identify genetic regions associated with MTX‐related neurotoxicity susceptibility ...
Rachel D. Harris +24 more
wiley +1 more source
Integrating brain organoids, meningeal immunity, and glymphatic dynamics: toward modeling neuroimmune clearance and crosstalk in disease. [PDF]
Wu X, Du B, Chen Q, Hang R, Cui C, Li M.
europepmc +1 more source
A Novel Choroid Segmentation Method for Retinal Diagnosis Using Deep Learning
Reliable choroid measurements have become an important diagnostic modality for sight-threatening retinal diseases. However, automatic and accurate segmentation of the choroid remains an unresolved challenge.
Al-Bander, Baidaa +4 more
core
ABSTRACT Juvenile xanthogranuloma (JXG) of the central nervous system (CNS) is a rare non‐Langerhans cell histiocytosis. CSF1R mutations have been reported for peripheral JXG, but not in CNS JXG. A 3‐month‐old male presented with fever, lymphadenopathy, and macrocephaly with bulging fontanelles.
Sima Vazquez +8 more
wiley +1 more source
Single-cell analysis of the epigenome and 3D chromatin architecture in the human retina. [PDF]
Yuan Y +26 more
europepmc +1 more source

