Results 151 to 160 of about 2,173,247 (301)
Experimental Physiology, EarlyView.Abstract High‐altitude chronic hypoxia can induce excessive erythrocytosis (EE, defined as a haemoglobin concentration of ≥21 g/dL in men), leading to hyperviscosity and promoting endothelial dysfunction. We aimed to assess whether EE affects the retinal vascular phenotype and the ophthalmological vascular response to CO2.
Aymeric Paillisser +12 more
wiley +1 more source
An Easy Guide to Rare Diseases in Ireland: A Resource for the Media and the General Public
, 2020 This ‘Easy Guide’ has been produced to increase awareness about the challenges of living with a rare disease and to highlight the priorities that need to be included in the forthcoming National Plan for Rare Diseases (NPRD) in Ireland. The aims of this
Task Force on Rare Diseases
core
TMEM16A channel signalling microdomains in the regulation of vascular function
The Journal of Physiology, EarlyView.Abstract figure legend Schematic representation of TMEM16A channel signalling microdomains. Calcium influx or calcium release from the endoplasmic/sarcoplasmic reticulum (ER/SR) activates TMEM16A channels through interactions with regulatory proteins in vascular smooth muscle cells or endothelial cells. TMEM16A channel activation drives chloride efflux,
Fênix Araujo, Swapnil K. Sonkusare
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Paracetamol (acetaminophen) is commonly taken during pregnancy for pain and fever. To gain a more comprehensive understanding of paracetamol's effects during pregnancy, several elements need to be examined including the transfer of paracetamol across the placenta and into the developing brain, the short‐ and long‐term effects of ...
Yifan Huang, Liam Koehn
wiley +1 more source
Recurrence of Vogt-Koyanagi-Harada Disease as Immune-Related Adverse Events Induced by an Immune Checkpoint Inhibitor. [PDF]
CureusFukushima A, Tabuchi H.
europepmc +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor +4 more
wiley +1 more source
Protect yourself from tickborne diseases [PDF]
"Ticks can be found in most of the United States, and many carry serious diseases. Some of the diseases that you can get from a tick bite include: anaplasmosis, babesiosis, Colorado tick fever, ehrlichiosis, Lyme disease, Powassan encephalitis, Q fever ...
core
The Journal of Physiology, EarlyView.Abstract figure legend This study assessed the impact of plasma‐derived small extracellular vesicles (sEVs) from healthy pregnant women and those diagnosed with late‐onset preeclampsia (PE) on the blood–brain barrier (BBB) integrity and glial cell response. PE patients had higher sEV concentrations than healthy controls.
Julián Henao‐Restrepo +7 more
wiley +1 more source
A Possible Link Between Cutaneous Melanoma and Uveal Melanoma: A Multicenter Retrospective Cohort Study. [PDF]
Cancers (Basel)Eiger-Moscovich M +5 more
europepmc +1 more source
Computational and Systems Oncology, Volume 6, Issue 1, December 2026.ABSTRACT Rare cancers collectively represent 20%–25% of all malignancies yet yield fewer than 50 annotated whole‐slide images (WSIs) per subtype in publicly available archives, rendering supervised deep learning inapplicable. We present HierAnom‐Path, to the best of our knowledge, the first framework for zero‐shot rare cancer anomaly detection in ...
Noora Saleem Jumaah +5 more
wiley +1 more source