Results 131 to 140 of about 2,173,247 (301)
Background Enteric infectious diseases claim more than 1 million lives annually and are among the top ten causes of death in children younger than 5 years.
GBD 2023 Diarrhoeal Disease and Enteric Infectious Diseases Collaborators +1 more
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Brain Pathology, EarlyView.Resource level‐based recommendations on practical diagnostic strategies for medulloblastomas and other CNS embryonal tumors are provided. Abstract WHO CNS5 mandates integrated histo‐molecular classification of medulloblastomas (MBs) and other CNS embryonal tumors. However, advanced molecular diagnostics remain inaccessible in many low‐ and lower‐middle‐
Chitra Sarkar +12 more
wiley +1 more source
Malignant progression in choroid plexus papillomas
, 2007 Object. Malignant progression of choroid plexus papillomas has been occasionally reported, but this issue has not yet been systematically addressed. Methods.
Paulus, Werner +5 more
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British Journal of Pharmacology, EarlyView.Abstract Opioids are prescribed widely for chronic pain despite well‐recognised risks and variable long‐term benefit, reflecting the lack of effective alternatives for many patients. Combination therapies offer a promising strategy to enhance efficacy whilst reducing side effects.
André Mouraux +26 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.Abstract Background and Purpose Asymmetrical dimethylarginine (ADMA) is an endogenous inhibitor of nitric oxide synthase (NOS), whereas dimethylaminohydrolase 1 (DDAH1) is primarily responsible for its metabolism. However, the roles of DDAH1 in cerebrovascular regulation are poorly understood. Furthermore, despite evidence that elevated ADMA levels are
Arun Flynn +10 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.The current obesity drug landscape, dominated by GLP‐1 receptor agonists and emerging multi‐agonist therapies, has reinforced that long‐term weight loss is achieved in large part through central mechanisms that suppress appetite and reshape energy balance.
Ines Martinez‐Corral +3 more
wiley +1 more source
Choroid Plexus Microstructural Alterations Link Glymphatic Dysfunction and White Matter Degeneration in Parkinson's Disease. [PDF]
CNS Neurosci TherThis study investigates the role of choroid plexus (CP) microstructural alterations in Parkinson's disease (PD), using free‐water corrected diffusion tensor imaging (FW‐DTI). Elevated CP diffusion metrics were linked to glymphatic dysfunction, corpus callosum degeneration, and worsened motor and cognitive performance in PD patients.
Zhou S +9 more
europepmc +2 more sources
Clinical &Experimental Ophthalmology, EarlyView.ABSTRACT Background To determine whether axial length‐related magnification correction in optical coherence tomography angiography (OCTA) improves machine learning classification of high myopia and resolves inconsistencies in the values and discriminatory power of OCTA microvascular metrics.
Danuta M. Sampson +9 more
wiley +1 more source
Report of the Advisory Committee on Communicable Diseases iin Prison [PDF]
, 1993 In 1990 the MInIster for JustIce announced the establIshment of an Advisory CommIttee on Communicable Diseases in Prisons with the following terms of reference:- "To examIne the problems posed by communIcable diseases affectIng offenders in prisons ...
Advisory Committee on Communicable Diseases in Prison
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Ocular Manifestations of Metabolic Syndrome: A Systemic Vascular Phenotype
Diabetes, Obesity and Metabolism, EarlyView.ABSTRACT Context Metabolic syndrome (MetS) is defined by central obesity, insulin resistance, hypertension and dyslipidemia. MetS affects over one‐third of US adults. Beyond its cardiovascular burden, MetS has clinically relevant associations with ocular health and may contribute to a systemic vascular and neuro‐metabolic phenotype involving the retina,
Ron T. Varghese, Ansu A. John
wiley +1 more source