Results 131 to 140 of about 49,505 (301)

Altered iron metabolism is part of the choroid plexus response to peripheral inflammation.

, 2009
Iron is essential for normal cellular homeostasis but in excess promotes free radical formation and is detrimental. Therefore, iron metabolism is tightly regulated.
Coppola, Giovanni, Geschwind, Daniel H., Neves, Margarida Correia, Falcão, Ana M., Sousa, Nuno, Marques, Fernanda, Sousa, João Carlos, Palha, Joana Almeida   +7 more
core   +1 more source

Neural modulation of ocular immunity: Exploring a sympathetic‐macrophage neuroimmune link in the human ciliary body

Journal of Anatomy, EarlyView.
Using microscopy and 3D confocal imaging on seven cadaveric eyes, we identified sympathetic nerves closely associated with β₂‐adrenergic receptor‐expressing macrophages in the human ciliary body (CB). These findings suggest a sympathetic‐macrophage neuroimmune link in the CB, potentially influencing ocular inflammation and degeneration, warranting ...
Tanya S. Karakyriakou, Claire Mackaaij, Mark van Zijverden, Hendrik A. Messal, Jeannette Ossewaarde‐van Norel, Ronald L. A. W. Bleys, Cindy G. J. Cleypool   +6 more
wiley   +1 more source

Pharmacokinetics of Diclazuril in the Plasma and Cerebrospinal Fluid of Healthy Adult Horses After a Single Oral Dose Administered as a Pelleted Topdressing

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT Equine protozoal myeloencephalitis can cause acute infections with rapid onset of neurologic signs, necessitating immediate empiric therapy with antiprotozoal medication. The objective of the study was to identify when concentrations of diclazuril reached the MIC of Sarcocystis neurona in CSF (1 ng/mL) of healthy adult horses after a single ...
Elizabeth J. Treece, Kate L. Hepworth‐Warren, Mark G. Papich, Philip D. van Harreveld, Anthony T. Blikslager, Faith E. Church, Kaitlyn B. Harbor, Sara J. Erwin‐Craig   +7 more
wiley   +1 more source

Choroid plexus -with special reference to neuroprotective function-

, 2012
Choroid plexus (CT) produces the cerebrospinal fluid (CSF) that fills the ventricles and subarachnoidal space, and infiltrates the intercellular spaces of CNS parenchyma. CP transplantation enhances axonal outgrowth in the spinal cord lesion.
Yamada, Yoshihiro, Nakano, Norihiko, Homma, Tamami, Ide, Chizuka   +3 more
core  

Techniques for subretinal injections in animals

Veterinary Ophthalmology, Volume 28, Issue 2, Page 506-518, March 2025.
Abstract Subretinal injections are not commonly performed during clinical treatment of animals but are frequently used in laboratory animal models to assess therapeutic efficacy and safety of gene and cell therapy products. Veterinary ophthalmologists are often employed to perform the injections in the laboratory animal setting, due to knowledge of ...
Ryan F. Boyd, Simon M. Petersen‐Jones
wiley   +1 more source

Stromal macrophages of the choroid plexus situated at an interface between the brain and peripheral immune system constitutively express major histocompatibility class II antigens

, 1992
Using immunocytochemistry we have shown that there is a population of macrophages within the stroma of the choroid plexus of rats and mice which expresses high levels of major histocompatibility complex Class II antigens.
Perry, V.H., Gordon, S., Matyszak, M.K., Lawson, L.J.   +3 more
core   +1 more source

An eye on long‐duration spaceflight: Controversies, countermeasures and challenges

Experimental Physiology, EarlyView.
Abstract Space flight‐associated neuroocular syndrome (SANS) is a consequence of long‐duration space flight and is detected in two‐thirds of astronauts. In‐flight, this can cause a change in the refraction of the eyes, requiring graded hypermetropic ‘superfocus adjustable’ glasses, optic nerve head oedema and choroidal folds.
Vincent Wing Sum Ng, Susan Patricia Mollan   +1 more
wiley   +1 more source

The Beijing angle closure progression study: design and methodology

Frontiers in Medicine
PurposeThe purpose of this study is to summarize the design and methodology of a large-scale trial in northern China, the Beijing Angle Closure Progression Study (BAPS).
Zhi-qiao Liang, Zhi-qiao Liang, Kang-yi Yang, Kang-yi Yang, Kun Lv, Kun Lv, Yao Ma, Yao Ma, Cun Sun, Ge Liang, Yan-kun Yue, Jia-yin Qin, Yao Zhao, Jia-nan Zhang, Qiong Yi, Xing-zhi Sun, Hui-juan Wu, Hui-juan Wu   +17 more
doaj   +1 more source

An introduction to choroid plexuses and their role in the glymphatic system [PDF]

Choroid plexuses are brain structures that contribute to the waste-clearance of the brain by secreting cerebrospinal fluid. In humans, four choroid plexuses are located in each of the four brain ventricles.
Väätäinen, Emma
core  

Neuroprotective roles of klotho: Molecular pathways and therapeutic implications for cognitive health in neurological and psychiatric diseases

Experimental Physiology, EarlyView.
Abstract Klotho, a pleiotropic protein initially identified for its role in kidney function, has garnered significant attention for its neuroprotective properties in various neurodegenerative diseases. It regulates key processes, such as oxidative stress, neuroinflammation, synaptic plasticity and myelination, all crucial for maintaining neuronal ...
Amir Arsalan Ghahari, Leylinaz Safaeihavadaragh, Mehrdad Nourizadeh, Shaghayegh Davari, Saba Safaei, Farshad Zare, Safa Alkayyat, Erfan Kamali Far   +7 more
wiley   +1 more source