Results 111 to 120 of about 49,505 (301)

Human brain matters: Navigating the neuropathology of COVID‐19

open access: yesBrain Pathology, EarlyView.
Severe COVID‐19 is associated with vascular dysregulation and chronic neuroinflammation, leading to axonal injury and neurodegeneration. In long COVID or PASC, persistent alterations in neuroimaging and biofluid biomarkers reflect ongoing neuronal damage and neuroinflammation, contributing to long‐term neurological symptoms including fatigue, cognitive
Juliana M. Nieuwland   +4 more
wiley   +1 more source

Effect of Ultrasound Radiation Force on the Choroid

open access: yes, 2013
Purpose: While visualization of the retina and choroid has made great progress, functional imaging techniques have been lacking. Our aim was to utilize acoustic radiation force impulse (ARFI) response to probe functional properties of these tissues ...
Lloyd, Harriet O.   +2 more
core   +1 more source

In silico prediction of novel effective combinational treatment of chronic pain in individual patients: A joint white paper of the H2020 QSPainRelief consortium

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Opioids are prescribed widely for chronic pain despite well‐recognised risks and variable long‐term benefit, reflecting the lack of effective alternatives for many patients. Combination therapies offer a promising strategy to enhance efficacy whilst reducing side effects.
André Mouraux   +26 more
wiley   +1 more source

Clinical outcomes of cyclophosphamide therapy in relentless placoid choroiditis: A descriptive case series

open access: yesIndian Journal of Ophthalmology
Purpose: To describe the clinical presentation and visual outcomes of relentless placoid choroiditis (RPC) in four patients treated with intravenous cyclophosphamide, a treatment not extensively studied in this condition.
Miguel Pedroza-Seres   +1 more
doaj   +1 more source

A Nationwide Central Diagnosis for Pediatric CNS Tumors in Japan: The JCCG Brain Tumor and Pathology Committees

open access: yesCancer Science, EarlyView.
In this report, we present the results of a nationwide initiative launched by the Japan Children's Cancer Group to provide integrated diagnoses for pediatric central nervous system (CNS) tumors, incorporating central pathological review and molecular profiling.
Yoshiko Nakano   +39 more
wiley   +1 more source

Aqueous Humour Cytokines as Predictors of Axial Elongation in High Myopia: A 2‐Year Longitudinal Cohort Study

open access: yesClinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background To investigate the predictive value of aqueous humour cytokines for axial elongation. Methods This was a prospective longitudinal observational study. 72 high myopia patients (72 eyes) who received implantable collamer lens (ICL) implantation surgery with at least 2 years of follow‐up were included.
Lihui Meng   +4 more
wiley   +1 more source

Choroidal metastases from thoracic cancer: a retrospective study on clinical characteristics and treatment efficacy

open access: yesFrontiers in Medicine
ObjectiveThis study aimed to examine the clinical characteristics of choroidal metastases (CMs) and assess the efficacy of various treatment strategies for CMs in a specific patient cohort.MethodsThis retrospective case series study included 32 patients (
Xiacheng Lin   +7 more
doaj   +1 more source

ChOP-CT: quantitative morphometrical analysis of the Hindbrain Choroid Plexus by X-ray micro-computed tomography

open access: yes
The Hindbrain Choroid Plexus is a complex, cerebrospinal fluid-secreting tissue that projects into the 4th vertebrate brain ventricle. Despite its irreplaceability in the development and homeostasis of the entire central nervous system, the research of ...
Zikmund, Tomáš   +17 more
core   +1 more source

Abnormal Glycaemic Fluctuations Associated With Early Microvascular Changes in the Retina and Choroid of Nondiabetic Adults

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To evaluate the association between continuous glucose monitoring (CGM)‐derived glycaemic variability indicators and early microvascular changes of the retina and choroid in nondiabetic individuals. Materials and Methods Community‐based individuals at high risk for type 2 diabetes (T2DM) underwent detailed assessments including oral ...
Yan Jiang   +15 more
wiley   +1 more source

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