Results 91 to 100 of about 2,173,247 (301)

Innovative PLA or PCL‐Based Ocular Implants Obtained From Tape Casting or Electrospinning for Sustained‐Release Dexamethasone

Journal of Applied Polymer Science, EarlyView.
PLA and PCL ocular implants prepared by tape casting and electrospinning provide sustained dexamethasone release with distinct release profiles governed by polymer type and processing method. The relationship between polymer structure, degradation behavior, and drug release demonstrates the potential of these fabrication techniques for controlled ...
Renata Bochanoski, Henrique Borba Modolon, Ronaldo Silveira, Januara Rodrigues, Tiago Bender Wermuth, Sabrina Arcaro, Oscar R. K. Montedo   +6 more
wiley   +1 more source

Low‐contrast visual acuity versus low‐luminance visual acuity in choroideremia

Clinical and Experimental Optometry, EarlyView., 2020
Clinical relevance Choroideremia is a progressive X‐linked inherited rod‐cone dystrophy. Patients present with nyctalopia and progressive visual field loss, but visual acuity remains well preserved early on. This study showed that low‐luminance visual acuity may be a useful clinical outcome measure during earlier disease stages.
Laura J Wood, Jasleen K Jolly, Colm D Andrews, Iain R Wilson, Doron Hickey, Jasmina Cehajic‐Kapetanovic, Robert E MacLaren   +6 more
wiley   +1 more source

Choroidal Findings in Systemic Diseases

Güncel Retina Dergisi (Current Retina Journal), 2022
The choroidal layer, which comprises the posterior part of uveal tissue and is responsible for the nutrition of the posterior third of the retina, has the highest blood flow per unit tissue. Metabolic diseases like hypertension, diabetes and systemic diseases such as hemoglobinopathies, blood dyscrasias, and autoimmune diseases may affect this highly ...
openaire   +1 more source

Choroid plexus tumours

, 2017
Choroid plexus tumours are rare, intraventricular, primary central nervous system tumours derived from the choroid plexus epithelium. They occur predominantly in children and are classified based on histological criteria as choroid plexus papilloma ...
Maria Santos, Eric Bouffet, Carolyn Freeman, Mark M. Souweidane   +3 more
core   +1 more source

Monitoring pharmacodynamic and molecular drug targets in liquid biopsy: Exploratory study in liver cancer with modelling of EGFR Receptor engagement

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Liquid biopsy is minimally invasive (compared with tissue biopsy) and has previously been used to generate systems data regarding drug elimination via hepatic enzymes and transporters. This study extends quantitative assessment of systems parameters in liquid biopsy to pharmacodynamic (PD) and disease markers relevant to cancer development
Zubida M. Al‐Majdoub, Armin Sepp, Amin Rostami‐Hodjegan, Brahim Achour   +3 more
wiley   +1 more source

Choroid Plexus Abnormalities in Autoimmune Encephalitis. [PDF]

CNS Neurosci Ther
Choroid plexus (ChP) enlargement is a robust AE imaging biomarker, with independent prognostic value for AEAE and poor outcomes. ChP MRI radiomic model predicts AEAE well, leveraging shape features to provide effective predictive performance for AEAE. Multi‑omics links ChP enlargement to reduced glutamatergic synapse pathway activity and enhanced PI3K ...
Sun Y, Wang N, Ge S, Feng L, Wang Q.
europepmc   +2 more sources

Sex-Specific Changes in Choroid Vasculature Among Patients with Schizophrenia and Bipolar Disorder

, 2022
Chloe Y Li,1,* Itika Garg,1,2,* Deepthi Bannai,3 Megan Kasetty,1 Raviv Katz,1,2 Iniya Adhan,3 Konstantinos AA Douglas,1 Jay C Wang,1 Leo A Kim,2 Matcheri Keshavan,3 Paulo Lizano,3,* John B Miller1,2,* 1Harvard Retinal Imaging Laboratory ...
Bannai D, Kasetty M, Kim LA, Lizano P, Li CY, Katz R, Wang JC, Adhan I, Keshavan M, Garg I, Douglas KAA, Miller JB   +11 more
core  

QUANTITATIVE ANALYSIS OF STRUCTURAL ALTERATIONS IN THE CHOROID OF PATIENTS WITH ACTIVE BEHÇET UVEITIS

, 2018
Purpose: To quantitatively analyze in vivo morphology of subfoveal choroid during an acute attack of Behcet ...
Herbort, C.P., Uludag, Gunay, Gunay Uludag, Uludag, G., Merih Oray, Akbay, Aylin Koc, Sumru Onal, Ilknur Tugal-Tutkun, Aylin Koc Akbay, Onal, Sumru, Metin, Mustafa M., Metin, M.M., Herbort, Carl P., Carl P. Herbort, Emre Mengi, Akman, M., Mengi, Emre, Mengi, E., Tugal-Tutkun, Ilknur, Onal, S., Mehmet Akman, Tugal-Tutkun, I., Mustafa M. Metin, Oray, M., Oray, Merih, AKMAN, MEHMET, Koc Akbay, A.   +26 more
core   +1 more source

A Novel Potential Pathway Linking Cardiac Diseases and Cognitive Dysfunction: Impaired Brain Glymphatic Function

Brain Health, EarlyView.
ABSTRACT Growing evidence confirms that cardiac diseases and cognitive dysfunction are closely related. Multiple cardiac diseases have been identified as important risk factors for cognitive impairment and dementia. Notably, recent studies suggest that cardiac diseases are associated not only with vascular cognitive impairment but also with an ...
Jiahuan Guo, Yuliang Qin, Xingquan Zhao
wiley   +1 more source

Febrile status epilepticus and epileptogenesis: The FEBSTAT study

Epilepsia Open, EarlyView.
Abstract The multicenter FEBSTAT study (Consequences of Prolonged Febrile Seizures in Childhood: https://grantome.com/grant/NIH/R37‐NS043209‐12; PI S. Shinnar) examined the outcome of febrile status epilepticus (FSE) in over 200 prospectively enrolled infants, with many followed for 10 years after FSE.
Darrell V. Lewis, Douglas R. Nordli Jr., Douglas R. Nordli III, Shlomo Shinnar, Stephen Chan, Jacqueline A. Bello, L. Matthew Frank, James Voyvodic, William Gallentine, Syndi Seinfeld, Yoshimi Sogawa, Erica Weiss, David Masur, Yuan Xu, Solomon L. Moshé   +14 more
wiley   +1 more source