Results 81 to 90 of about 49,505 (301)

Altered secretory and neuroprotective function of the choroid plexus in progressive multiple sclerosis [PDF]

, 2020
The choroid plexus (CP) is a key regulator of the central nervous system (CNS) homeostasis through its secretory, immunological and barrier properties.
Kooji, Gjis, Kooij, Gijs, Bruggmann, Rémy, Ferreira Francisco, David Miguel, de Vries, Helga, Ishikawa, Hiroshi, Vos, Ricardo, Rijnsburger, Merel, De Vries, Helga E., Van Het Hof, Bert, Schroten, Horst, Beaino, Wissam, Rodríguez-Lorenzo, Sabela   +12 more
core   +1 more source

Homogenous Cell Transplantation Trials in Parkinson's Disease: A Systematic Review and Meta‐Analysis

Movement Disorders Clinical Practice, EarlyView.
Abstract Background The transplantation of homogenous cells has emerged as an investigational strategy for Parkinson's disease (PD), offering an alternative to symptomatic treatment. Objective We performed a systematic review and meta‐analysis to assess its clinical efficacy and safety.
Nolan Reinisch, Athena Mancini, Adham Elsherbini, Jason Yuen, Andres Lozano   +4 more
wiley   +1 more source

A Novel Choroid Segmentation Method for Retinal Diagnosis Using Deep Learning

, 2017
Reliable choroid measurements have become an important diagnostic modality for sight-threatening retinal diseases. However, automatic and accurate segmentation of the choroid remains an unresolved challenge.
Majid A. Al-Taee, Baidaa Al-Bander, Al-Bander, Baidaa, Williams, Bryan M., Yalin Zheng, Al-Nuaimy, Waleed, Bryan M. Williams, Al-Taee, Majid A., Zheng, Yalin, Waleed Al-Nuaimy   +9 more
core   +1 more source

Research status and trends of Piezo1 and brain: A bibliometric analysis

Neuroprotection, EarlyView.
This graphical abstract illustrates the workflow and key findings of the bibliometric analysis of Piezo1 in brain research. The primary results were visually centered on a brain graphic highlighting the Piezo1 channel, and three converging research hotspots were identified: neurovascular regulation, calcium signaling, and neuroinflammation.
Yu Liu, Shengzhen Luo, Hao Zhang, Jianqing Lin, Hui Xiao, Yuying Ma, Dongxue Ye, Liang Cong, Yongwang Li   +8 more
wiley   +1 more source

The Ocular Biometry of Adult Cataract Patients on Lifeline Express Hospital Eye-Train in Rural China

Journal of Ophthalmology, 2015
Aims. To describe and explore the distribution of ocular biometric parameters of adult cataract patients in rural China. Methods. Three Lifeline Express Hospital Eye-Train missions of Peking University People’s Hospital in China were chosen.
Xiaoguang Cao, Xianru Hou, Yongzhen Bao
doaj   +1 more source

Structural and functional features of choroid epithelium from buffalo brain.

, 2007
Choroid plexuses (CPs) play pivotal roles in many processes that establish, survey, and maintain the biochemical and cellular status of the central nervous system (CNS).
DE GIROLAMO, PAOLO, PAVONE, LUIGI MICHELE, SCALA, GAETANO, PELAGALLI, ALESSANDRA, STAIANO, NORMA, M. CORONA   +5 more
core   +1 more source

Current Insight into Human Ornithine Aminotransferase: A Review

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Human ornithine aminotransferase (hOAT) is a mitochondrial matrix pyridoxal‐5′‐phosphate enzyme (PLP) that catalyzes the reversible transfer of the δ‐amino group of L‐ornithine (L‐Orn) to α‐ketoglutarate (α‐KG) yielding glutamate‐5‐semialdehyde (GSA) and glutamate. GSA is prone to cyclize to Δ1‐pyrroline‐5‐carboxylate.
Fulvio Floriani, Carla Borri Voltattorni, Riccardo Montioli   +2 more
wiley   +1 more source

Clinical reasoning in feline non‐ambulatory tetraparesis or tetraplegia: Which combination of clinical information is useful?

Veterinary Record, EarlyView.
Abstract Background Non‐ambulatory tetraparesis or tetraplegia in cats may constitute a diagnostic challenge for general practitioners. Therefore, this study aimed to evaluate if clinical variables from signalment, history, clinical examination and basic ancillary tests are associated with underlying diagnoses in cats with non‐ambulatory tetraparesis ...
Guido Bertoldi, Steven De Decker
wiley   +1 more source

Recent progress on the development of hydrogel‐based microneedles for transdermal drug delivery

VIEW, EarlyView.
This study provides a comprehensive and up‐to‐date analysis of recent progress in HMN technology, covering fundamental transdermal delivery mechanisms and design principles, biomaterials used in HMN fabrication, drug loading and release strategies, and emerging therapeutic applications.
Mohammad Muhtasim Ittisaf, Salman Farsi Taharat, Md. Sadek Miah, Hasan Tasnim Salehin, M. Azam Ali, Shoeb Ahmed   +5 more
wiley   +1 more source

Infection control in the brain and the eye

Acta Ophthalmologica, EarlyView.
Abstract The Central Nervous System (CNS), comprising the brain and the eye, is considered to have a ‘privileged’ mechanism for dealing with immunological challenge (immune privilege, IP). CNS IP has been revealed through experiments using foreign protein antigens and cell and tissue alloantigens (grafts), but evidence for a role for IP in modulating ...
John V. Forrester, Paul G. McMenamin, Samantha J. Dando   +2 more
wiley   +1 more source