Results 71 to 80 of about 48,314 (255)
British Journal of Clinical Pharmacology, EarlyView.Abstract Aim Liquid biopsy is minimally invasive (compared with tissue biopsy) and has previously been used to generate systems data regarding drug elimination via hepatic enzymes and transporters. This study extends quantitative assessment of systems parameters in liquid biopsy to pharmacodynamic (PD) and disease markers relevant to cancer development
Zubida M. Al‐Majdoub +3 more
wiley +1 more source
Febrile status epilepticus and epileptogenesis: The FEBSTAT study
Epilepsia Open, EarlyView.Abstract The multicenter FEBSTAT study (Consequences of Prolonged Febrile Seizures in Childhood: https://grantome.com/grant/NIH/R37‐NS043209‐12; PI S. Shinnar) examined the outcome of febrile status epilepticus (FSE) in over 200 prospectively enrolled infants, with many followed for 10 years after FSE.
Darrell V. Lewis +14 more
wiley +1 more source
Homogenous Cell Transplantation Trials in Parkinson's Disease: A Systematic Review and Meta‐Analysis
Movement Disorders Clinical Practice, EarlyView.Abstract Background The transplantation of homogenous cells has emerged as an investigational strategy for Parkinson's disease (PD), offering an alternative to symptomatic treatment. Objective We performed a systematic review and meta‐analysis to assess its clinical efficacy and safety.
Nolan Reinisch +4 more
wiley +1 more source
Movement Disorders Clinical Practice, EarlyView.Abstract Background Neurodegeneration with Brain Iron Accumulation (NBIA) is a heterogeneous group of heritable, mostly recessive, progressive neurodegenerative diseases characterized by iron deposition in the basal ganglia and brainstem. There are no solid global epidemiological data on prevalence and incidence of NBIA subtypes, but registry data and ...
Susanne A. Schneider +3 more
wiley +1 more source
Using Manganese‐Enhanced DCE‐MRI to Assess Blood‐Cerebrospinal Fluid Barrier Transport
Magnetic Resonance in Medicine, EarlyView.ABSTRACT Purpose We developed a dynamic, heavily T2‐weighted (hT2w) FLAIR protocol to resolve acute Mn2+ transport kinetics, as a proxy for Ca2+, across the choroid plexus (ChP)—cerebrospinal fluid (CSF) interface, in vivo. By quantifying intercompartmental Mn2+ dynamics, and comparing these with Gd‐DOTA, we sought to characterize blood‐CSF‐barrier ...
Charith Perera +9 more
wiley +1 more source
Veterinary Record, EarlyView.Abstract Background Non‐ambulatory tetraparesis or tetraplegia in cats may constitute a diagnostic challenge for general practitioners. Therefore, this study aimed to evaluate if clinical variables from signalment, history, clinical examination and basic ancillary tests are associated with underlying diagnoses in cats with non‐ambulatory tetraparesis ...
Guido Bertoldi, Steven De Decker
wiley +1 more source
Frontiers in MedicineBackgroundSeveral nutrients have been found to be associated with the prevalence of myopia, and the role of dietary patterns in influencing myopia risk has recently garnered significant attention.
Xiaodong Chen +26 more
doaj +1 more source
Recent progress on the development of hydrogel‐based microneedles for transdermal drug delivery
VIEW, EarlyView.This study provides a comprehensive and up‐to‐date analysis of recent progress in HMN technology, covering fundamental transdermal delivery mechanisms and design principles, biomaterials used in HMN fabrication, drug loading and release strategies, and emerging therapeutic applications.
Mohammad Muhtasim Ittisaf +5 more
wiley +1 more source
CLASSIFICATION OF DISEASES OF THE CHOROID [PDF]
British Journal of Ophthalmology, 1924 openaire +9 more sources
Indian Journal of Ophthalmology, 2018 A structurally and functionally intact choroid tissue is vitally important for the retina function. Although central retinal artery is responsible to supply the inner retina, choroidal vein network is responsible for the remaining one-third of the ...
Francesco Pichi +7 more
doaj +1 more source