Results 61 to 70 of about 70,682 (288)

Analysis of macular structure in age-related cataract patients with different antibody levels of severe acute respiratory syndrome coronavirus-2 vaccine

Frontiers in Immunology, 2022
ObjectiveTo analyze the macular structure of age-related cataract (ARC) patients with different antibody levels after COVID-19 vaccine injection, in order to obtain the effect of COVID-19 vaccine on the macular structure, and speculate whether the COVID ...
Xiaochun Li, Xiaochun Li, Xiaoguang Cao, Zhongting Pan, Xinping Sun, Yongzhen Bao   +5 more
doaj   +1 more source

Murine MPDZ-linked hydrocephalus is caused by hyperpermeability of the choroid plexus. [PDF]

, 2019
Though congenital hydrocephalus is heritable, it has been linked only to eight genes, one of which is MPDZ Humans and mice that carry a truncated version of MPDZ incur severe hydrocephalus resulting in acute morbidity and lethality.
Byrne, Matthew D., Horowitz, Arie, Ishikawa, Hiroshi, Kilker, Robert, Londin, Eric, Nichtova, Zuzana, Oakley, Laura, Pardeep-Kumar, Fnu, Pickup, Stephen, Saugier-Veber, Pascale, Schroten, Horst, Simonneau, Claire, Smeyne, Richard, Stefanescu, Ioana, Thakur, Mathew, Tripathi, Sushil, Willard, Belinda, Yang, Junning   +17 more
core   +2 more sources

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

elastography in primary open-angle glaucoma [PDF]

, 2016
Objective: The aim of this study was to compare sonoelastographic findings in the retina-choroid-sclera (RCS) complex and vitreous in glaucomatous and healthy eyes.Methods: For this cross-sectional comparative study, 20 patients with primary open-angle ...
Agladioglu, K, Kasikci, SA, Kiroglu, Y, Pekel, G, Yagci, R   +4 more
core   +2 more sources

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

A comparison between the therapeutic effects of Conbercept combined with panretinal photocoagulation and panretinal photocoagulation monotherapy for high-risk proliferative diabetic retinopathy

Frontiers in Endocrinology, 2023
ObjectiveTo compare the therapeutic effects of the administration of intravitreal Conbercept (IVC) plus panretinal photocoagulation (PRP) to that of PRP monotherapy in patients with high-risk proliferative diabetic retinopathy (PDR).MethodsIn this ...
Yaoyao Sun, Yaoyao Sun, Yaoyao Sun, Yaoyao Sun, Huijun Qi, Huijun Qi, Huijun Qi, Huijun Qi   +7 more
doaj   +1 more source

'Unforgettable' : a pictorial essay on anatomy and pathology of the hippocampus [PDF]

, 2017
The hippocampus is a small but complex anatomical structure that plays an important role in spatial and episodic memory. The hippocampus can be affected by a wide range of congenital variants and degenerative, inflammatory, vascular, tumoral and toxic ...
Achten, Eric, Acou, Marjan, DE GROOTE, JEROEN, De Kock, Isabelle, Deblaere, Karel, Dekeyzer, Sven, Nikoubashman, Omid, VAN EETVELDE, RUTH, Vanden Bossche, Stephanie, Wiesmann, Martin   +9 more
core   +2 more sources

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao, Rong Li, Yu‐Xiang Jiao, Kai Ma, Hong‐Qi Yang, Zheng‐Yu Sun, Jie‐Wen Zhang, Shuai Chen   +7 more
wiley   +1 more source

Choroidal Excavation in Vogt-Koyanagi-Harada Disease [PDF]

Case Reports in Ophthalmology, 2014
<b><i>Purpose:</i></b> To report a case of choroidal excavation accompanied by Vogt-Koyanagi-Harada disease (VKH). <b><i>Methods:</i></b> A 54-year-old Japanese woman who was complaining of bilateral blurring of vision associated with headache underwent optical coherence tomography (OCT), fluorescein ...
Noriyasu Hashida, Andrew Fok, Kohji Nishida   +2 more
openaire   +3 more sources

Choroid Plexus Enlargement and USPIO‐Based Inflammatory Feature in Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The choroid plexus (CP) is a key component of the blood–cerebrospinal fluid barrier (BCSFB), but its mechanism of action in cerebral small vessel disease (CSVD) remains unclear. This study investigated CP volume (CPV) alterations and their association with conventional imaging markers in CSVD and explored the underlying role of ...
Yongqiang Qu, Xiaoning Ren, Cuihua Fan, Chun Li, Lijie Zhang, Zaiqiang Zhang, Shaowu Li, Zhongmeng Lai, Bin Cai, Ying Fu, Yi Lin, Zhibao Zhu   +11 more
wiley   +1 more source