Results 61 to 70 of about 48,314 (255)

The analysis of foveal microvascular anomalies in retinopathy of prematurity after anti-vascular endothelial growth factor therapy using optical coherence tomography angiography

open access: yesBMC Ophthalmology
Background To investigate the quantitative vascular and structural differences in the foveal region of the eyes in retinopathy of prematurity children with or without anti-vascular endothelial growth factor (VEGF) therapy and healthy children using ...
Wenbo Liu   +10 more
doaj   +1 more source

From Flexible to Conformable Pressure Sensors: Mechanisms, Materials, and Biomedical Applications

open access: yesAdvanced Electronic Materials, EarlyView.
This review highlights recent progress, challenges and future opportunities in pressure sensing for advanced biomedical applications. We summarize key transduction mechanisms and emerging material strategies, discuss representative wearable and implantable applications for continuous physiological monitoring and provide a focused perspective on barrier
Rishabh B. Mishra   +2 more
wiley   +1 more source

Choroidal involvement in systemic vasculitis: a systematic review

open access: yesJournal of Ophthalmic Inflammation and Infection, 2022
Systemic vasculitides are a large group of heterogeneous diseases characterized by inflammatory destruction of blood vessels targeting diverse organs and tissues including the eye.
Pınar Çakar Özdal   +1 more
doaj   +1 more source

Clinical, Behavioral and Neuroradiological Phenotype in an Italian Cohort of Patients With Xia Gibbs Syndrome: A Multicenter Cross‐Sectional Study and Systematic Literature Review

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Heterozygous variants in the AHDC1 gene are associated with Xia Gibbs Syndrome (XGS), a genetic disorder with a highly variable phenotype. Cognitive impairment, motor delay, language delay, neonatal hypotonia, and sleep apnea are considered “cardinal” signs of the disease.
Giulia Cinelli   +18 more
wiley   +1 more source

The process of retinal vascularization in retinopathy of prematurity after ranibizumab treatment in China [PDF]

open access: yesInternational Journal of Ophthalmology, 2019
AIM: To explore the process of retinal vascularization and risk factors for retinopathy of prematurity (ROP) treated with intravitreal ranibizumab (IVR) as monotherapy.
Qing-Yu Meng   +3 more
doaj   +1 more source

ApoE‐ and Cfh‐deficient mice exhibit structural and molecular features of human early–intermediate retinal degeneration

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Age‐related macular degeneration (AMD) involves lipid dysregulation and complement overactivation. Here, we characterize a double‐knockout ApoE−/−/Cfh−/− mouse as a model of early–intermediate retinal degeneration. These mice exhibit retinal pigment epithelium thinning, Bruch's membrane thickening, lipid accumulation, enhanced C5b‐9 deposition ...
Sergio Recalde   +9 more
wiley   +1 more source

Small Interfering RNA Targeted to ASPP2 Promotes Progression of Experimental Proliferative Vitreoretinopathy

open access: yesMediators of Inflammation, 2016
Background. Epithelial-mesenchymal transition (EMT) of retinal pigment epithelium (RPE) is vital in proliferative vitreoretinopathy (PVR) development.
Xiao-Li Chen   +5 more
doaj   +1 more source

Single‐cell atlas of neuroglial dynamics in SNCA‐A53T Parkinson's disease mouse model

open access: yesAnimal Models and Experimental Medicine, EarlyView.
We performed single‐cell RNA sequencing of midbrain and striatal tissues from SNCA‐A53T Parkinson's disease (PD) mice, revealing glia‐enriched PD‐risk gene signatures and disease‐specific subpopulations. Transcriptional dysregulation of key TFs (e.g., Rorb, Foxc1) and enhanced neuroinflammatory signaling (SEMA, CCL, MIF) were identified.
Binqing Qin   +7 more
wiley   +1 more source

Choroidal Findings in Systemic Diseases

open access: yesGüncel Retina Dergisi (Current Retina Journal), 2022
The choroidal layer, which comprises the posterior part of uveal tissue and is responsible for the nutrition of the posterior third of the retina, has the highest blood flow per unit tissue. Metabolic diseases like hypertension, diabetes and systemic diseases such as hemoglobinopathies, blood dyscrasias, and autoimmune diseases may affect this highly ...
openaire   +1 more source

The Ocular Biometry of Adult Cataract Patients on Lifeline Express Hospital Eye-Train in Rural China

open access: yesJournal of Ophthalmology, 2015
Aims. To describe and explore the distribution of ocular biometric parameters of adult cataract patients in rural China. Methods. Three Lifeline Express Hospital Eye-Train missions of Peking University People’s Hospital in China were chosen.
Xiaoguang Cao, Xianru Hou, Yongzhen Bao
doaj   +1 more source

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