Results 51 to 60 of about 2,322,168 (296)

Continuous High-Dose (6 mg) vs. Low-Dose (3 mg) Intravitreal Ganciclovir for Cytomegalovirus Retinitis After Haploidentical Hematopoietic Stem Cell Transplantation: A Randomized Controlled Study

Frontiers in Medicine, 2021
Purpose: To evaluate the safety and efficacy of continuous high-dose (6 mg) intravitreal ganciclovir injections (IVG) for cytomegalovirus (CMV) retinitis (CMVR) after haploidentical hematopoietic stem cell transplantation (Haplo-HSCT), and to explore ...
Wei-Bin Chen, Wei-Bin Chen, Wei-Bin Chen, Wei-Bin Chen, Ze Long, Ze Long, Ze Long, Ze Long, Jing Hou, Jing Hou, Jing Hou, Jing Hou, Heng Miao, Heng Miao, Heng Miao, Heng Miao, Ming-wei Zhao, Ming-wei Zhao, Ming-wei Zhao, Ming-wei Zhao   +19 more
doaj   +1 more source

The Choroid Plexus in Healthy and Diseased Brain [PDF]

Journal of Neuropathology & Experimental Neurology, 2016
The choroid plexus is composed of epithelial cells resting on a basal lamina. These cells produce the cerebrospinal fluid (CSF), which has many functions including rendering mechanical support, providing a route for some nutrients, removing by-products of metabolism and synaptic activity, and playing a role in hormonal signaling.
Charanjit, Kaur, Gurugirijha, Rathnasamy, Eng-Ang, Ling   +2 more
openaire   +2 more sources

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Direct observation and measurement of circumlental space and its relation to anterior chamber angle characteristics in iridotomized phakic eyes with primary angle closure disease

Scientific Reports
Primary angle closure disease (PACD) is a major cause of blindness worldwide. It has a high prevalence in East Asia, especially in China, which leads to a higher incidence of blindness than open-angle glaucoma.
Zhiqiao Liang, Kangyi Yang, Kun Lv, Yao Ma, Xuanzhu Chen, Zeqin Ren, Yong Liang, Xianru Hou, Huijuan Wu   +8 more
doaj   +1 more source

Unilateral isolated optic nerve infiltration combined with central retinal artery occlusion in a patient with acute myeloid leukemia

American Journal of Ophthalmology Case Reports, 2022
Purpose: To report a case of unilateral isolated optic nerve infiltration combined with central retinal artery occlusion in a patient with acute myeloid leukemia.
Chen Zhao, Duo Wei, Xuan Shi, Mingwei Zhao   +3 more
doaj   +1 more source

ube3d, a New Gene Associated with Age-Related Macular Degeneration, Induces Functional Changes in Both In Vivo and In Vitro Studies

Molecular Therapy: Nucleic Acids, 2020
Neovascular age-related macular degeneration (AMD) is characterized by the formation of choroidal neovascularization, which is responsible for more than 80% of cases of severe vision loss.
Huika Xia, Qi Zhang, Yan Shen, Yujing Bai, Xiaoyun Ma, Bo Zhang, Yun Qi, Jingjing Zhang, Qinrui Hu, Wei Du, Li Zhu, Peng Zhou, Bin Wang, Hui Xu, Lvzhen Huang, Xiaoxin Li   +15 more
doaj   +1 more source

Analysis of macular structure in age-related cataract patients with different antibody levels of severe acute respiratory syndrome coronavirus-2 vaccine

Frontiers in Immunology, 2022
ObjectiveTo analyze the macular structure of age-related cataract (ARC) patients with different antibody levels after COVID-19 vaccine injection, in order to obtain the effect of COVID-19 vaccine on the macular structure, and speculate whether the COVID ...
Xiaochun Li, Xiaochun Li, Xiaoguang Cao, Zhongting Pan, Xinping Sun, Yongzhen Bao   +5 more
doaj   +1 more source

Eales Disease Associated With Serpiginous Choroiditis [PDF]

Archives of Ophthalmology, 2012
Eales disease is an idiopathic, usually bilateral, inflammatory, retinal vascular occlusive disorder. Serpiginous choroiditis is an idiopathic, usually bilateral, recurrent acute progressive inflammation of the inner choroid and retinal pigment epithelium. To our knowledge, we describe the first case of Eales disease followed by serpiginous choroiditis.
Adrian T. Fung, NICOLO', MASSIMO, Susanne Yzer, TRAVERSO, CARLO, Lawrence A. Yannuzzi   +4 more
openaire   +1 more source

A Retinal Matrix Stiffening Model Reveals FAK‐Dependent Mechanotransduction in Pericytes Underlies Vascular Destabilization

Advanced Materials, EarlyView.
In this study, we show that retinal matrix stiffness is increased in diabetic mice. Using engineered human vascular models with controlled matrix stiffness, we demonstrate that stiffening activates focal adhesion kinase (FAK) signaling in pericytes, suppresses Notch signaling, and disrupts vascular morphology.
Emily Warren, Alex Wu, Lucas Ramirez, Yaqing Huang, Connor Amelung, Sophia Saxonhouse, Sharon Gerecht   +6 more
wiley   +1 more source

Ultrastructural characteristics of the trabecular meshwork in primary open-angle glaucoma versus chronic angle-closure glaucoma: a comparative study

BMC Ophthalmology
Background The trabecular meshwork (TM), the principal site of aqueous humor outflow resistance, plays a pivotal role in the regulation of intraocular pressure (IOP), the key modifiable risk factor for glaucoma.
Zhiqiao Liang, Kuankuan Wu, Ye Lu, Fengrui Yang, Kun Lv, Huichao Yan, Yanan Hu, Huijuan Wu   +7 more
doaj   +1 more source