Results 101 to 110 of about 2,173,247 (301)

Association of dietary inflammatory index and refractive status in American adolescents: NHANES 1999–2008

open access: yesFrontiers in Medicine
BackgroundSeveral nutrients have been found to be associated with the prevalence of myopia, and the role of dietary patterns in influencing myopia risk has recently garnered significant attention.
Xiaodong Chen   +26 more
doaj   +1 more source

SpaceNet: Pathology‐guided analysis of lesion‐associated spatial molecular programs

open access: yesiMetaOmics, EarlyView.
Disease‐associated molecular alterations are often confined to localized pathological regions, yet current spatial transcriptomic analyses do not always use pathology or imaging information as the primary reference for defining disease‐relevant spatial contexts.
Menglei Wang   +5 more
wiley   +1 more source

Choroidal biomarkers

open access: yesIndian Journal of Ophthalmology, 2018
A structurally and functionally intact choroid tissue is vitally important for the retina function. Although central retinal artery is responsible to supply the inner retina, choroidal vein network is responsible for the remaining one-third of the ...
Francesco Pichi   +7 more
doaj   +1 more source

Neurogenic effects of β-amyloid in the choroid plexus epithelial cells in Alzheimer's disease

open access: yes, 2013
β-amyloid (Aβ) can promote neurogenesis, both in vitro and in vivo, by inducing neural progenitor cells to differentiate into neurons. The choroid plexus in Alzheimer's disease (AD) is burdened with amyloid deposits and hosts neuronal progenitor cells ...
Ordóñez-Gutiérrez, Lara   +6 more
core   +1 more source

Targeting the Choroid Plexuses for Protein Drug Delivery

open access: yes, 2020
Delivery of therapeutic agents to the central nervous system is challenged by the barriers in place to regulate brain homeostasis. This is especially true for protein therapeutics. Targeting the barrier formed by the choroid plexuses at the interfaces of
Anthony M. Snyder   +4 more
core   +1 more source

Precision Medicine in Neurodegeneration with Brain Iron Accumulation (NBIA) Disorders: An Update on Emerging Treatments

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Neurodegeneration with Brain Iron Accumulation (NBIA) is a heterogeneous group of heritable, mostly recessive, progressive neurodegenerative diseases characterized by iron deposition in the basal ganglia and brainstem. There are no solid global epidemiological data on prevalence and incidence of NBIA subtypes, but registry data and ...
Susanne A. Schneider   +3 more
wiley   +1 more source

Advancing Artificial Intelligence in Myopia Management: From Predicting Progression to Supporting Clinical Decisions

open access: yesMed Research, EarlyView.
The AI‐enabled multimodal framework for whole‐life myopia management. Graphical abstract illustrates the transition of myopia care from premyopia to myopia, high myopia, and pathologic myopia. Multimodal data, including demographic and refractive information, genetic, behavioral and environmental factors, ophthalmic imaging, and omics profiles, can be ...
Zewei Zhang   +6 more
wiley   +1 more source

National Clinical Programme for Rare Diseases Workshop on Clinical Research in Rare Diseases

open access: yes, 2018
The National Clinical Programme was established in December 2013. It is an initiative of the HSE, in partnership with the Royal College of Physicians. A key objective of the Clinical Programme for Rare Diseases is to improve access for rare diseases ...
National Clinical Programme for Rare Diseases
core  

Parkinson's Disease and Retinal Age Gap: A Cross‐Sectional Analysis

open access: yesMovement Disorders, EarlyView.
Abstract Background Deep‐learning models are capable of predicting age from retinal scans and the difference between this and chronological age, retinal age gap, has been shown to be significantly associated with risk of mortality, cardiovascular diseases, and kidney failure.
Akshay Narayan   +9 more
wiley   +1 more source

Normal growth curve of choroid plexus in children: implications for assessing hydrocephalus due to choroid plexus hyperplasia [PDF]

open access: yes
Hashimoto H., Takemoto O., Nishimoto K., et al. Normal growth curve of choroid plexus in children: implications for assessing hydrocephalus due to choroid plexus hyperplasia.
Moriguchi, Gento   +5 more
core   +1 more source

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