Results 101 to 110 of about 13,733 (229)

A Benign Giant Fibroblastic Intraventricular Meningioma: A Rare Case Report with Review of Literature

Medical Journal of Dr. D.Y. Patil Vidyapeeth
Intraventricular meningiomas are uncommon neoplasms and account for only 0.5 to 3%. They are seen mostly in the age group of 12 to 14 years. They arise from the arachnoid cap cells located in the choroid plexus.
Shirish S. Chandanwale, Neil A. Shah, Namit Gupta   +2 more
doaj   +1 more source

FABP4‐mediated lipid droplet accumulation drives epithelial–mesenchymal transition and aggravates alveolar epithelial barrier disruption

Clinical and Translational Medicine, Volume 16, Issue 1, January 2026.
LIRI induces FABP4 secretion, driving lipid droplets accumulation in alveolar epithelial cells. FABP4 activates p38 MAPK/ULK1 signalling to inhibit lipophagy and promote lipid storage. Lipid droplets trigger epithelial–mesenchymal transition and disrupt alveolar barrier. Elevated FABP4 predicts ARDS in cardiopulmonary bypass patients.
Zihao Shen, Yuanpu Qi, Mingyu Chu, Minchao Wu, Chen Feng, Xiangyu Li, Zhaoyang Liu, Linjie Si, Yongliang Wang, Jialin Zhang, Xiaoning Lu, Peng Lu   +11 more
wiley   +1 more source

Modulators of Diacylglycerol Kinase Activity: A Review of Advances and Challenges

Medicinal Research Reviews, Volume 46, Issue 1, Page 149-175, January 2026.
ABSTRACT Catalyzing the conversion of diacylglycerol (DAG) in phosphatidic acid (PA), diacylglycerol kinases (DGKs) play a pivotal role in all the physiological processes modulated by these two bioactive lipids, such as lipid metabolism and immune regulation.
Luisa Racca, Gianluca Baldanzi, Alberto Massarotti   +2 more
wiley   +1 more source

Clinical Features and Treatment Strategies of Li‐Fraumeni Syndrome Patients With Inherited TP53 Mutations

Molecular Genetics &Genomic Medicine, Volume 14, Issue 1, January 2026.
LFS with TP53 disease‐causing mutations may be potential beneficiaries of immune checkpoint inhibitors and targeted therapies. Therefore, NGS and PD‐L1 testing should be performed in all LFS patients. ABSTRACT Background Li‐Fraumeni syndrome is a rare autosomal dominant disorder caused by a pathogenic mutation of the tumor suppressor gene TP53.
Keyu Chen, Yufen Xu, Binbin Song, Yuyang Gu, Xiaofang Xu, Jun Cao, Meiyu Fang   +6 more
wiley   +1 more source

Cholesteatoma and hydrocephalus associated to a third ventricle meningioma in a cat

Ciência Rural
: Meningiomas are neoplasms that commonly involve the central nervous system of cats, while cholesteatomas are nodular granulomatous chronic lesions within the choroid plexus that are rarely reported in cats. This study described a case of cholesteatoma
Maria Fernanda Wentz, Thainã Piccolo Vargas, Matheus Viezzer Bianchi, Rochana Rodrigues Fett, Cíntia De Lorenzo, Saulo Petinatti Pavarini   +5 more
doaj   +1 more source

Advances in Deep Learning Applications for Choroidal Images Analysis: A Narrative Review

IET Image Processing, Volume 20, Issue 1, January/December 2026.
Clinical detection and evaluation of the choroid primarily rely on imaging and subsequent image analysis. The application of artificial intelligence (AI), particularly deep learning (DL), in the analysis of choroidal images shows significant potential for improving accuracy and efficiency.
Yiwen Shi, Zixuan Jiang, Ziyi Yang, Houjin Chen, Xuemin Li, Jiarui Yang   +5 more
wiley   +1 more source

Pediatric brain tumor classification using digital pathology and deep learning: Evaluation of SOTA methods on a multi‐center Swedish cohort

Brain Pathology, Volume 36, Issue 1, January 2026.
Deep learning‐based feature extractors pretrained on histopathology images can classify pediatric brain tumors when applied to a multi‐center Swedish dataset. Abstract Brain tumors are the most common solid tumors in children and young adults, but the scarcity of large histopathology datasets has limited the application of computational pathology in ...
Iulian Emil Tampu, Per Nyman, Christoforos Spyretos, Ida Blystad, Alia Shamikh, Gabriela Prochazka, Teresita Díaz de Ståhl, Johanna Sandgren, Peter Lundberg, Neda Haj‐Hosseini   +9 more
wiley   +1 more source

Histogram Analysis Parameters ADC for Distinguishing Ventricular Neoplasms of Ependymoma, Choroid Plexus Papilloma, and Central Neurocytoma

, 2019
Chen Chen, Cuiping Ren, Rui-chen Zhao, Jiangwei Ding, Jingliang Cheng   +4 more
openalex   +2 more sources

P53 expression in choroid plexus neoplasms: an immunohistochemical study.

Archives of pathology & laboratory medicine, 2002
To evaluate choroid plexus neoplasms for p53 expression.We studied 10 choroid plexus tumors (four papillomas and six carcinomas) by immunohistochemistry using the DO7 anti-p53 monoclonal antibody.Three of four choroid plexus papillomas demonstrated no staining. Scattered nuclear and rare cytoplasmic positivity was present in one papilloma, which showed
V, Jay, M, Ho, F, Chan, D, Malkin
openaire   +1 more source

Chronic Basal Ganglia Infarction With PCR‐Identified Paeniclostridium sordellii: A Rare Neuropathological Case Report

Case Reports in Pathology, Volume 2026, Issue 1, 2026.
Background Within 1 month of diagnosis, 40% of patients with positive blood cultures will develop CNS complications. Rare pathogens, that is, Paeniclostridium sordellii, pose diagnostic challenges due to atypical presentations and detection difficulties. Case Presentation A 67‐year‐old man presented with metabolic encephalopathy and diabetes insipidus.
Cassandra Lamm, Angus Toland, Samuel Guzman, Amit Agrawal   +3 more
wiley   +1 more source