Results 81 to 90 of about 16,798 (239)
Infection control in the brain and the eye
Acta Ophthalmologica, EarlyView.Abstract The Central Nervous System (CNS), comprising the brain and the eye, is considered to have a ‘privileged’ mechanism for dealing with immunological challenge (immune privilege, IP). CNS IP has been revealed through experiments using foreign protein antigens and cell and tissue alloantigens (grafts), but evidence for a role for IP in modulating ...
John V. Forrester +2 more
wiley +1 more source
Clinical Characteristics of Choroidal Metastases
OkulistykaThe most common intraocular tumors in adults are metastases from primary tumors: breast cancer, lung cancer, and other organ neoplasms. They are most typically located in the choroid, in the posterior pole of the eye.
Bożena Romanowska-Dixon +5 more
doaj +1 more source
Ocular manifestations in Gorlin-Goltz syndrome [PDF]
, 2019 Background: Gorlin-Goltz syndrome, also known as nevoid basal cell carcinoma syndrome, is a rare genetic disorder that is transmitted in an autosomal dominant manner with complete penetrance and variable expressivity.
Franzone, F. +8 more
core +1 more source
Acta Ophthalmologica, EarlyView.Abstract Purpose To examine the age distribution and characteristics of choroidal nevi in a large nationwide sample. Methods We included all individuals who underwent fundus photography in a nationwide chain of optometry stores during a 5‐week period in 2023.
Carsten Faber +3 more
wiley +1 more source
Possibilities for Identifying the Malignant Vasculature of Choroidal Melanoma
Oftalʹmologiâ, 2020 Choroidal melanoma is the most common and life-threatening intraocular malignant neoplasm affecting the eye choroid in about 90 % of cases. The incidence varies from 0.7 to 1.1 per 100,000 of the population. This category of malignant neoplasms is highly
E. V. Samkovich, I. E. Panova
doaj +1 more source
Delta-like 4 inhibits choroidal neovascularization despite opposing effects on vascular endothelium and macrophages.: DLL4's opposing effects in choroidal neovascularization [PDF]
, 2012 International audienceInflammatory neovascularization, such as choroidal neovascularization (CNV), occur in the presence of Notch expressing macrophages. DLL4s anti-angiogenic effect on endothelial cells (EC) has been widely recognized, but its influence
Calippe, Bertrand +16 more
core +4 more sources
Atypical choroid plexus papilloma treated with single agent bevacizumab
Rare Tumors, 2014 Choroid plexus papillomas (CPPs) are usually not malignant and occur in less than 1% of brain tumors in patients of all ages. They represent 3% of childhood intracranial neoplasms with a predilection in younger ages.
Francois G. Kamar +4 more
doaj +1 more source
Exploring the interdependencies of research funders in the UK [PDF]
, 2014 Investment in medical research is vital to the continuing improvement of the UK's health and wealth. It is through research that we expand our understanding of disease and develop new treatments for patients.
Crane, P +13 more
core +1 more source
Human brain matters: Navigating the neuropathology of COVID‐19
Brain Pathology, EarlyView.Severe COVID‐19 is associated with vascular dysregulation and chronic neuroinflammation, leading to axonal injury and neurodegeneration. In long COVID or PASC, persistent alterations in neuroimaging and biofluid biomarkers reflect ongoing neuronal damage and neuroinflammation, contributing to long‐term neurological symptoms including fatigue, cognitive
Juliana M. Nieuwland +4 more
wiley +1 more source
The first pancreatic neuroendocrine tumor in Li-Fraumeni syndrome: a case report
BMC Cancer, 2020 Background Li-Fraumeni syndrome is a cancer predisposition syndrome caused by germline TP53 tumor suppressor gene mutations, with no previous association with pancreatic neuroendocrine tumors (PNETs).
John G. Aversa +8 more
doaj +1 more source