Results 71 to 80 of about 14,649 (206)

Infantile Central Nervous System Juvenile Xanthogranuloma With Somatic CSF1R Mutation Responsive to Imatinib Monotherapy

open access: yesPediatric Blood &Cancer, Volume 73, Issue 10, October 2026.
ABSTRACT Juvenile xanthogranuloma (JXG) of the central nervous system (CNS) is a rare non‐Langerhans cell histiocytosis. CSF1R mutations have been reported for peripheral JXG, but not in CNS JXG. A 3‐month‐old male presented with fever, lymphadenopathy, and macrocephaly with bulging fontanelles.
Sima Vazquez   +8 more
wiley   +1 more source

Atypical choroid plexus papilloma: a case report and literature review

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2012
Objective To report a rare case of atypical choroid plexus papilloma and explore its clinical presentations and histopathological features, at the same time to take a review of relevant literature.
Meng YAN   +6 more
doaj  

Longitudinal trends in Gamma Knife radiosurgery utilization across multiple technological generations: A Single‐Institution Observational Study

open access: yesJournal of Applied Clinical Medical Physics, Volume 27, Issue 10, October 2026.
Abstract Background Gamma Knife radiosurgery (GKRS) has been a foundational modality for the treatment of intracranial diseases for several decades, with successive platform generations introducing substantial technological advancements. Improvements in source configuration, patient positioning systems, imaging guidance, and immobilization techniques ...
Daniel El Basha   +11 more
wiley   +1 more source

From Molecular Targets to Advanced Delivery Systems: Aptamers for Precision Ocular Therapeutics

open access: yesAdvanced Therapeutics, Volume 9, Issue 10, October 2026.
Aptamer‐based strategies are revolutionizing ocular disease management through highly specific molecular recognition of disease specific molecular targets. This review systematically integrates therapeutic aptamer sequences, diagnostic aptasensor platforms, and targeted delivery strategies, highlighting design principles, ocular bioavailability ...
Minal Thacker   +4 more
wiley   +1 more source

Canine Primary Intracranial Cancer: A Clinicopathologic and Comparative Review of Glioma, Meningioma, and Choroid Plexus Tumors

open access: yesFrontiers in Oncology, 2019
In the dog, primary intracranial neoplasia represents ~2–5% of all cancers and is especially common in certain breeds including English and French bulldogs and Boxers. The most common types of primary intracranial cancer in the dog are meningioma, glioma,
Andrew D. Miller   +2 more
doaj   +1 more source

Large‐scale Whole‐Exome Sequencing Defines the Protein‐Coding Architecture of Retinal Structure, Visual Function, and Major Blinding Diseases

open access: yesAdvanced Science, Volume 13, Issue 56, 9 October 2026.
Large‐scale whole‐exome sequencing in 356,982 UK Biobank participants defines the protein‐coding architecture of retinal structure, visual function, and major blinding diseases. Pleiotropic genes, including CFI, C3, and RIOX1, bridge multiple retinal phenotypes, while experimental validation of FYB2 implicates RPE barrier dysfunction, providing ...
Jianqing Li   +23 more
wiley   +1 more source

Nanoprobe‐Enabled Precision Imaging and Panoramic Boundary Delineation in Retinoblastoma

open access: yesCancer Innovation, Volume 5, Issue 5, October 2026.
This review highlights that nanoprobe‐enabled multimodal imaging, combined with targeted probe design and AI‐assisted analysis, significantly enhances the precise visualization and boundary delineation of retinoblastoma. It further outlines key challenges and directions for translating high‐performance imaging nanoprobes into clinical practice.
Xuefei He   +7 more
wiley   +1 more source

PAPILLARY GLIONEURONAL TUMOR OF THE POSTERIOR FOSSA

open access: yesRevista Ciencias Biomédicas, 2015
Introduction: the papillary glioneuronal tumor (PGT) is an uncommon disease and it has recent categorization. It has probable origin in the pluripotent stem cells of the subependymal zone that is located mainly around the temporal horns of the lateral
Tuñón-Pitalúa Martha Cecilia   +5 more
doaj  

Outcomes of adult patients with Li‐Fraumeni syndrome and myeloid neoplasms

open access: yesCancer, Volume 132, Issue 19, 1 October 2026.
Abstract Background Li‐Fraumeni syndrome (LFS) is an inherited cancer predisposition syndrome. Hematologic malignancies are not considered LFS defining tumors, however, both acute lymphoblastic leukemia and therapy‐related myeloid neoplasms (MNs) in LFS are described. Treatment approaches and outcomes of MN in LFS need further evaluation.
Jayastu Senapati   +19 more
wiley   +1 more source

A rare trifocal presentation of a choroid plexus papilloma: Case report and review of the literature

open access: yesBrain and Spine
Introduction: CPP's present as slow-growing intraventricular neoplasms arising from epithelium of choroid plexus. They account for approximately 0.5–4% of intracranial neoplasms in adults and children, respectively. A trifocal presentation is exceedingly
Senne Broekx, Mania De Praeter
doaj   +1 more source

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