Results 121 to 130 of about 41,786 (283)

Suprachiasmatic Nuclei Possess Glucocorticoid Receptors That Activate Downstream Signaling Pathways but Do Not Entrain Their Circadian Clock

open access: yesActa Physiologica, Volume 242, Issue 1, January 2026.
ABSTRACT Aim The circadian clock in the suprachiasmatic nuclei of the hypothalamus (SCN) is resistant to glucocorticoids (GC) in adults but responds to dexamethasone (DEX) during the fetal stage. Previously, this resistance of the adult SCN clock was attributed to a developmental loss of the glucocorticoid receptor (GR).
Martin Sládek   +3 more
wiley   +1 more source

Choroid Plexus Metastasis of Colon Cancer

open access: diamond, 2003
Kazuhiro Kitajima   +3 more
openalex   +2 more sources

Pediatric brain tumor classification using digital pathology and deep learning: Evaluation of SOTA methods on a multi‐center Swedish cohort

open access: yesBrain Pathology, Volume 36, Issue 1, January 2026.
Deep learning‐based feature extractors pretrained on histopathology images can classify pediatric brain tumors when applied to a multi‐center Swedish dataset. Abstract Brain tumors are the most common solid tumors in children and young adults, but the scarcity of large histopathology datasets has limited the application of computational pathology in ...
Iulian Emil Tampu   +9 more
wiley   +1 more source

Quantity and Volume of Perivascular Spaces Are Inversely Associated With Multiple Sclerosis Relative to Cerebrovascular Disease and Migraine

open access: yesAnnals of Clinical and Translational Neurology, Volume 12, Issue 12, Page 2569-2574, December 2025.
ABSTRACT Objective To quantify the number and volume of whole brain perivascular spaces (PVS) using a detection and segmentation algorithm in participants with multiple sclerosis (MS) and patients with disorders mimicking MS known to potentially influence PVS, such as cerebrovascular disease.
Elle M. Levit   +5 more
wiley   +1 more source

Choroid plexus papilloma

open access: hybrid, 2014
Yusra Sheikh, Frank Gaillard
openalex   +1 more source

Single‐Cell Dissection of the Biological Function and Molecular Features Underlying the Micropeptide LSMEM1 in Kidney

open access: yesAdvanced Science, Volume 12, Issue 48, December 29, 2025.
LSMEM1, an evolutionarily conserved micropeptide with extreme hydrophobicity (aliphatic index═113) and dynamic amphiphilicity (GRAVY═0.017), features a strong α‐helical transmembrane anchor (residues 64‐86). Single‐cell analysis reveals its critical role in renal lipid homeostasis.
Peimin Liu   +11 more
wiley   +1 more source

The Multifaceted Etiology of Mental Disorders With a Focus on Trace Elements, a Review of Recent Literature

open access: yesAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics, Volume 198, Issue 8, Page 168-189, December 2025.
ABSTRACT Mental disorders are a significant global public health concern, affecting nearly one in eight individuals worldwide. This review investigates the multifaceted etiology of mental disorders—specifically major depressive disorder (MDD), schizophrenia (SCZ), and bipolar disorder (BD)—through genetic, neurobiological, and environmental ...
Maria Francesca Astorino   +8 more
wiley   +1 more source

CSF metabolomic signatures across five proteomic subtypes in patients with Alzheimer's disease

open access: yesAlzheimer's &Dementia, Volume 21, Issue S1, December 2025.
Abstract Background Alzheimer's disease (AD) is marked by molecular heterogeneity. We previously identified five distinct molecular AD subtypes based on CSF proteomics: neuronal hyperplasticity (S1), innate immune activation (S2), RNA dysregulation (S3), choroid plexus dysfunction (S4), and blood–brain barrier impairment (S5).
Georgia Malliou   +7 more
wiley   +1 more source

Neuropathology, Localized Proteomics, and Imaging of the Choroid Plexus across the Alzheimer's Disease Continuum

open access: yesAlzheimer's &Dementia, Volume 21, Issue S1, December 2025.
Abstract Background The choroid plexus (ChP), a highly vascularized structure within the ventricles, plays a vital role in cerebrospinal fluid (CSF) production and metabolic waste clearance, essential for brain homeostasis and function. In vivo imaging studies have identified age‐ and Alzheimer's disease (AD)‐related ChP changes, including increased ...
Dominique Leitner   +11 more
wiley   +1 more source

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