Results 161 to 170 of about 41,786 (283)
A Real World Study of Aducanumab Treatment in Patients with Early Alzheimer’s Disease in China
Abstract Background The aggregation of amyloid‐β (Aβ) is widely regarded as a key factor in the pathogenesis of Alzheimer’s disease (AD). The aducanumab was the first anti‐Aβ monoclonal body clinically used in China. Methods It was a 12‐month, single‐center, real‐world study to observe the efficacy and safety of aducanumab in early AD in Chinese ...
Gang Wang
wiley +1 more source
Rapid malignant progression of an intraparenchymal choroid plexus papillomas [PDF]
Rosario Maugeri +10 more
openalex +1 more source
Refining early tau‐PET staging using CA1 and prosubiculum rather than the whole hippocampus
Abstract Background Early tau positron emission tomography (PET) regions of interest (ROIs) either consider the whole hippocampus or wholly excludes it. However, only the cornu ammonis 1 (CA1) and prosubiculum are specifically afflicted by tau pathology in histopathological examinations (1).
Etienne Aumont +13 more
wiley +1 more source
Developmental Characterization of the Choroid Plexus in Sialidosis (Neu1 Deficient) Mice
Danielle Helton
openalex +1 more source
Significance of sonographically detected second‐trimester choroid plexus cysts: a series of 211 cases and a review of the literature [PDF]
Santiago Nava +4 more
openalex +1 more source
Ventricle Enlargement is Negatively Correlated with Aβ38 in human CSF
Abstract Background Senile plaques in Alzheimer’s disease (AD) primarily consist of Aβ42, while Aβ38 is a shorter isoform cleaved from Aβ42. Higher cerebrospinal fluid (CSF) Aβ38 levels have been linked to slower cognitive decline and a reduced risk of developing AD dementia. Ventricular enlargement, a CSF‐related abnormality in AD, is characterized by
Yansheng Zheng +25 more
wiley +1 more source
Automated synthetic contrast-enhanced MRI improves choroid plexus segmentation in Parkinsonian syndromes. [PDF]
Ambaye DT +11 more
europepmc +1 more source
Abstract Background Pro‐inflammatory astrocyte activation, choroid plexus dysfunction, and ventricular enlargement may collectively impair cerebrospinal fluid (CSF) clearance, a process which removes metabolic waste, including amyloid‐β and tau. Dysregulated clearance mechanisms may contribute to Alzheimer’s disease pathogenesis (AD) by facilitating ...
Seyyed Ali Hosseini +16 more
wiley +1 more source

