Results 11 to 20 of about 166,293 (242)

Morphology of the murine choroid plexus: Attachment regions and spatial relation to the subarachnoid space

Frontiers in Neuroanatomy, 2022
The choroid plexus has recently been identified as a possible migration route for peripheral immune cells into the central nervous system. For future investigation of this route, profound knowledge of the morphology of the murine choroid plexus is a ...
Theresa Greiner, Katerina Manzhula, Louise Baumann, Hannes Kaddatz, Jens Runge, Jens Runge, Jonas Keiler, Markus Kipp, Sarah Joost   +8 more
doaj   +1 more source

Cerebrospinal fluid production by the choroid plexus: a century of barrier research revisited

Fluids and Barriers of the CNS, 2022
Cerebrospinal fluid (CSF) envelops the brain and fills the central ventricles. This fluid is continuously replenished by net fluid extraction from the vasculature by the secretory action of the choroid plexus epithelium residing in each of the four ...
N. MacAulay, R. Keep, T. Zeuthen
semanticscholar   +1 more source

Choroid Plexus Volume in Multiple Sclerosis vs Neuromyelitis Optica Spectrum Disorder

Neurology, 2022
The choroid plexus has been shown to play a crucial role in CNS inflammation. Previous studies found larger choroid plexus in multiple sclerosis (MS) compared with healthy controls.
J. Müller, T. Sinnecker, M. Wendebourg, R. Schläger, J. Kuhle, Sabine Schädelin, P. Benkert, T. Derfuss, P. Cattin, C. Jud, Florian Spiess, M. Amann, T. Lincke, M. Barakovic, A. Cagol, C. Tsagkas, K. Parmar, Anne-Katrin Proebstel, Sophia Reimann, Susanna Asseyer, A. Duchow, A. Brandt, K. Ruprecht, N. Hadjikhani, Shoko Fukumoto, Mitsuru Watanabe, K. Masaki, T. Matsushita, N. Isobe, J. Kira, L. Kappos, J. Würfel, C. Granziera, F. Paul, Ö. Yaldizli   +34 more
semanticscholar   +1 more source

Choroid plexus volume in multiple sclerosis predicts expansion of chronic lesions and brain atrophy

Annals of Clinical and Translational Neurology, 2022
Recent studies suggested that the expansion of long‐standing multiple sclerosis (MS) lesions and an enlargement of choroid plexus may be linked to chronic inflammation and microglial activation.
S. Klistorner, Michael H Barnett, J. Parratt, C. Yiannikas, Stuart L. Graham, A. Klistorner   +5 more
semanticscholar   +1 more source

Translational value of choroid plexus imaging for tracking neuroinflammation in mice and humans

Proceedings of the National Academy of Sciences of the United States of America, 2021
Significance Neuroinflammation is a hallmark of multiple sclerosis and is linked to neurodegeneration. This study provides pathophysiological insights into the cross-dependency between neuroinflammation and choroid plexus characteristics in both mice and
V. Fleischer, G. González-Escamilla, D. Ciolac, P. Albrecht, P. Küry, J. Gruchot, Michael Dietrich, Christina Hecker, Thomas Müntefering, S. Bock, Mohammadsaleh Oshaghi, Angela Radetz, M. Cerina, J. Krämer, L. Wachsmuth, C. Faber, H. Lassmann, T. Ruck, S. Meuth, M. Muthuraman, Sergiu Groppa   +20 more
semanticscholar   +1 more source

Constitutive activation of canonical Wnt signaling disrupts choroid plexus epithelial fate

Nature Communications, 2022
The choroid plexus secretes cerebrospinal fluid and is critical for the development and function of the brain. In the telencephalon, the choroid plexus epithelium arises from the Wnt- expressing cortical hem.
Arpan Parichha, Varun Suresh, Mallika Chatterjee, Aditya Kshirsagar, Lihi Ben-Reuven, T. Olender, M. M. Taketo, V. Radošević, Mihaela Bobić-Rasonja, Sara Trnski, M. Holtzman, N. Jovanov-Milošević, O. Reiner, S. Tole   +13 more
semanticscholar   +1 more source

Targeting choroid plexus epithelium as a novel therapeutic strategy for hydrocephalus

Journal of Neuroinflammation, 2022
The choroid plexus is a tissue located in the lateral ventricles of the brain and is composed mainly of choroid plexus epithelium cells. The main function is currently thought to be the secretion of cerebrospinal fluid and the regulation of its pH, and ...
Yijian Yang, Jian He, Yuchang Wang, Chuansen Wang, Changwu Tan, Junbo Liao, Lei Tong, Gelei Xiao   +7 more
doaj   +1 more source

Choroid plexus NKCC1 mediates cerebrospinal fluid clearance during mouse early postnatal development

Nature Communications, 2021
Cerebrospinal fluid (CSF) provides vital support for the brain. Abnormal CSF accumulation, such as hydrocephalus, can negatively affect perinatal neurodevelopment.
Huixin Xu, Ryann M. Fame, Cameron Sadegh, J. Sutin, Christopher Naranjo, Della Syau, Jin Cui, Frederick B. Shipley, Amanda N Vernon, Fan Gao, Yong Zhang, M. Holtzman, M. Heiman, B. Warf, Pei-Yi Lin, Maria K. Lehtinen   +15 more
semanticscholar   +1 more source

An extremely rare case of choroid plexus carcinoma in the third ventricle of an infant – Case report and review of the literature

Interdisciplinary Neurosurgery, 2020
Background: Choroid plexus tumors are rare intraventricular tumors. Most of these tumors are benign choroid plexus papillomas. Choroid plexus carcinoma is the most malignant choroid plexus tumor and constitutes a small percentage of these tumors.
Amin Tavallaii, Ehsan Keykhosravi, Hamid Rezaee, Mohsen Khamoushi   +3 more
doaj   +1 more source

Increased cytokine expression in the choroid plexus stroma and epithelium in response to endotoxin-induced systemic inflammation in mice

Toxicology Reports, 2021
Sepsis-associated encephalopathy (SAE) is characterized as diffuse brain dysfunction in patients with excessive systemic inflammatory reaction to an infection.
Atsuyoshi Shimada, Sanae Hasegawa-Ishii
doaj   +1 more source