Results 41 to 50 of about 68,747 (311)

Choroid Plexus Pathophysiology

Annual Review of Pathology: Mechanisms of Disease
This review examines the roles of the choroid plexus (ChP) in central nervous system (CNS) pathology, emphasizing its involvement in disease mechanisms and therapeutic potential. Structural changes in the human ChP have been reported across various diseases in case reports and descriptive work, but studies have yet to pin down the physiological ...
Ya'el, Courtney, Alexandra, Hochstetler, Maria K, Lehtinen   +2 more
openaire   +2 more sources

Choroid Plexus Papilloma: A Case Report with Special Emphasis on Diagnosis and Pathology [PDF]

Journal of Clinical and Diagnostic Research
Choroid plexus papilloma is a rare, benign neuroepithelial tumour arising from the choroid plexus of the brain. It is reported to be more common in the lateral ventricles among paediatric populations and in the fourth ventricle in adults.
Apoorva Pande, Samarth Shukla, Milind Pande, Suhit Naseri, Saurabh Gawand   +4 more
doaj   +1 more source

Characterization of choroid plexus in the preterm rabbit pup following subcutaneous administration of recombinant human IGF-1/IGFBP-3

Fluids and Barriers of the CNS, 2023
Insulin-like growth factor-1 (IGF-1) is essential for normal brain development and regulates essential processes of vascular maturation and stabilization. Importantly, preterm birth is associated with reduced serum levels of IGF-1 as compared to in utero
Niklas Ortenlöf, Suvi Vallius, Helena Karlsson, Claes Ekström, Amanda Kristiansson, Bo Holmqvist, Olga Göransson, Magdaléna Vaváková, Martin Rydén, Galen Carey, Norman Barton, David Ley, Magnus Gram   +12 more
doaj   +1 more source

Persistent Wnt/β-catenin signaling determines dorsalization of the postnatal subventricular zone and neural Stem cell specification into oligodendrocytes and glutamatergic neurons [PDF]

, 2014
In the postnatal and adult central nervous system (CNS), the subventricular zone (SVZ) of the forebrain is the main source of neural stem cells (NSCs) that generate olfactory neurons and oligodendrocytes (OLs), the myelinating cells of the CNS.
Azim, Kasum, Butt, Arthur, Cantu, Claudio, Draganova, Kalina, Fischer, Bruno, Hurtado-Chong, Anahi, Raineteau, Olivier, Sommer, Lukas, Zemke, Martina   +8 more
core   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

Transport of thyroid hormones via the choroid plexus into the brain: the roles of transthyretin and thyroid hormone transporters

Frontiers in Neuroscience, 2015
Thyroid hormones (THs) are key players in regulating brain development. In humans, insufficient THs during gestation can lead to cretinism and mental retardation.
Samantha J. Richardson, Roshen C. Wijayagunaratne, Damian G. D'Souza, Veerle M. Darras, Stijn L. J. Van Herck   +4 more
doaj   +1 more source

Telovelar approach for microsurgical resection of an unusually located choroid plexus papilloma in the luschka foramen of an infant – Case report and review of literature

Interdisciplinary Neurosurgery, 2020
Background: Choroid plexus tumors are rare intraventricular tumors. Most of these tumors are benign choroid plexus papillomas. Most common location of these tumors in pediatric population is lateral ventricle although posterior fossa located tumors are ...
Amin Tavallaii, Ehsan Keykhosravi, Hamid Rezaee   +2 more
doaj   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Control of cell division in the adult brain by heparan sulfates in fractones and vascular basement membranes [PDF]

, 2010
Regulation of cell division in adult tissues and organs requires the coordination of growth factors at the surface of potentially-dividing cells in specific anatomic loci named germinal niches.
Frederic Mercier, Vanessa Douet
core   +1 more source

Altered iron metabolism is part of the choroid plexus response to peripheral inflammation. [PDF]

, 2009
Iron is essential for normal cellular homeostasis but in excess promotes free radical formation and is detrimental. Therefore, iron metabolism is tightly regulated.
Coppola, Giovanni, Falcão, Ana M., Geschwind, Daniel H., Marques, Fernanda, Neves, Margarida Correia, Palha, Joana Almeida, Sousa, João Carlos, Sousa, Nuno   +7 more
core   +1 more source