International Journal of Molecular Sciences, 2020 Accumulation of amyloid-beta (Aβ) in the brain is thought to derive from the impairment of Aβ clearance mechanisms rather than from its overproduction, which consequently contributes to the development of Alzheimer’s disease.
A. C. Duarte +8 more
semanticscholar +1 more source
Molecular cloning and characterization of B-cadherin, a novel chick cadherin. [PDF]
, 1991 Calcium-dependent cell-cell adhesion is mediated in large part by a set of homologous integral membrane glycoproteins termed cadherins. In this report, antibodies to conserved domains in previously described cadherins have been used to isolate cDNAs ...
Napolitano, EW +3 more
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Epigenetics impacts upon prognosis and clinical management of choroid plexus tumors
Journal of Neuro-Oncology, 2020 Purpose Choroid plexus tumors comprise of choroid plexus papilloma (CPP, WHO grade I), atypical choroid plexus papilloma (aCPP, WHO grade II) and choroid plexus carcinoma (CPC, WHO grade III).
C. Thomas +4 more
semanticscholar +1 more source
Choroid plexus volume enlargement in first-episode antipsychotic-naïve schizophrenia
SchizophreniaInvestigation of the choroid plexus in schizophrenia has seen growing interest due to its role in the interaction between neuroinflammation and brain dysfunction. Most previous studies included treated and long-term ill patients, while antipsychotics and
Jiaxin Zeng +12 more
doaj +1 more source
Third ventricle choroid plexus papilloma: 2 cases
Radiology Case Reports, 2020 The third ventricle is an uncommon location for choroid plexus papillomas. In adults, these tumors most commonly occur in the fourth ventricle. In children, they are more commonly found in the lateral ventricles.
Cory M. Pfeifer, MD, MS +5 more
doaj +1 more source
The systemic environment: at the interface of aging and adult neurogenesis. [PDF]
, 2017 Aging results in impaired neurogenesis in the two neurogenic niches of the adult mammalian brain, the dentate gyrus of the hippocampus and the subventricular zone of the lateral ventricle.
Smith, Lucas K +2 more
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Identification and characterization of FAM124B as a novel component of a CHD7 and CHD8 containing complex [PDF]
, 2012 BACKGROUND: Mutations in the chromodomain helicase DNA binding protein 7 gene (CHD7) lead to CHARGE syndrome, an autosomal dominant multiple malformation disorder. Proteins involved in chromatin remodeling typically act in multiprotein complexes.
Batsukh, Tserendulam +7 more
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Multicilia dynamically transduce Sonic Hedgehog signaling to regulate choroid plexus functions
Cell ReportsSummary: The choroid plexus is a major site for cerebrospinal fluid (CSF) production, characterized by a multiciliated epithelial monolayer that regulates CSF production.
Suifang Mao +21 more
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Ion channel function of aquaporin-1 natively expressed in choroid plexus [PDF]
, 2006 Aquaporins are known as water channels; however, an additional ion channel function has been observed for several including aquaporin-1 (AQP1). Using primary cultures of rat choroid plexus, a brain tissue that secretes CSF and abundantly expresses AQP1 ...
Boassa, D., Stamer, W., Yool, A.
core +1 more source
A cellular and spatial map of the choroid plexus across brain ventricles and ages
bioRxiv, 2019 The choroid plexus (ChP), located in each brain ventricle, produces cerebrospinal fluid (CSF) and forms the blood-CSF barrier, but is under-characterized.
Neil Dani +15 more
semanticscholar +1 more source