Results 51 to 60 of about 6,243 (171)

Reduced folate receptor alpha (FOLR1) protein expression in fallopian tubes from premenopausal women: implications for the FOLR1 CDx assay for mirvetuximab‐soravtansine therapy

The Journal of Pathology: Clinical Research, Volume 12, Issue 3, May 2026.
Abstract Mirvetuximab‐soravtansine (MIRV‐S) is an antibody‐drug conjugate targeting folate receptor alpha (FOLR1). MIRV‐S is approved for the treatment of FOLR1‐positive, platinum‐resistant ovarian carcinoma. Patient eligibility is determined by immunohistochemistry (IHC) using a companion diagnostic (CDx) assay (FOLR1‐2.1, Ventana).
Annika Nasdala, Leonie D Kandt, Martin Radner, Nora Schaumann, Malte Gronewold, Pia Hillmann, Henriette Christgen, Jens Hachenberg, Elna Kuehnle, Christian Hartmann, Matthias Christgen   +10 more
wiley   +1 more source

Carcinoma bilateral do plexo coróide operado com sucesso Bilateral carcinoma of the choroid plexus operated successfully

Arquivos de Neuro-Psiquiatria, 1970
Os autores não encontraram na literatura caso de carcinoma bilateral do plexo coróide operado com sucesso. O trabalho consta da apresentação de uma criança de 11 anos com carcinoma dos plexos coróides nos dois ventrículos laterais.
Gilberto M. de Almeida, Charles P. Tilbery, Luiz G. Gagliardi-Ferreira   +2 more
doaj  

Leptomeningeal Dissemination in Choroid Plexus Tumors: Magnetic Resonance Imaging Appearance and Risk Factors

Children
Background: Intracranial choroid plexus tumors (CPT) are rare and primarily affect young children. Leptomeningeal dissemination (LMD) has been reported not only in high-grade choroid plexus carcinoma (CPC) but also in lower histological grades; however ...
Daniel Nunes do Espirito Santo, Monika Warmuth-Metz, Camelia-Maria Monoranu, Martin Hasselblatt, Christian Thomas, Torsten Pietsch, Jürgen Krauß, Tilmann Schweitzer, Brigitte Bison, Matthias Eyrich, Uwe Kordes, Denise Obrecht-Sturm, Mirko Pham, Annika Quenzer   +13 more
doaj   +1 more source

Choroid plexus carcinoma enmasked with soft signs and symptoms

Indian Journal of Medical and Paediatric Oncology, 2019
Choroid plexus carcinomas (CPCs) are rare brain tumors, with preponderance in infants. They are highly invasive tumors with a dismal prognosis. The 5-year survival rates for CPC vary between 10% and 50%.
Shruti Appaji, K NV Prasad
doaj   +1 more source

Indirubin and Retinoic Acid Show Binding Affinity to Monocyte Biomarker CSF3R in Parkinson's Disease

Journal of Clinical Laboratory Analysis, Volume 40, Issue 8, April 2026.
Through single‐cell RNA‐sequencing and high‐dimensional weighted gene co‐expression network analysis, two monocyte‐related biomarkers (CSF3R, IFITM3) were identified in the peripheral blood of Parkinson's disease. Molecular docking revealed two targeted drugs (Indirubin and Retinoic acid).
Zhiwei Bao, Shao Zhi, Mao Jie
wiley   +1 more source

Neoadjuvant Chemotherapy in Choroid Plexus Carcinoma: Improving Surgical Safety and Resection Outcomes

Journal of the Pakistan Medical Association
Choroid plexus carcinoma (CPC) is a rare and highly vascular malignant brain tumour that occurs mainly in children. Complete surgical resection offers the best chance of long-term survival, but this is often difficult due to excessive intraoperative ...
Mubashirah Sajid Charolia, Fatima Suleman, Muhammad Shahzad Shamim   +2 more
doaj   +1 more source

Intraocular Metastasis: Differential Diagnosis and Management

Clinical &Experimental Ophthalmology, Volume 54, Issue 3, Page 382-397, April 2026.
ABSTRACT Intraocular metastases represent the most common type of malignant intraocular tumour in adults. These commonly affect the choroid but can also involve the iris, ciliary body, retina, vitreous, optic disc or lens. Breast and lung cancer are the most common origins of intraocular metastases.
Genovefa Μachairoudia, Dimitrios Kazantzis, Guy S. Negretti, Mandeep S. Sagoo   +3 more
wiley   +1 more source

Insights Into the Antigenic Repertoire of Unclassified Synaptic Antibodies

Annals of Clinical and Translational Neurology, Volume 13, Issue 3, Page 547-561, March 2026.
ABSTRACT Objective We sought to characterize the sixth most common finding in our neuroimmunological laboratory practice (tissue assay‐observed unclassified neural antibodies [UNAs]), combining protein microarray and phage immunoprecipitation sequencing (PhIP‐Seq). Methods Patient specimens (258; 133 serums; 125 CSF) meeting UNA criteria were profiled;
Michael Gilligan, John R. Mills, Paulina Vargas, Naveen K. Paramasivan, Connie E. Lesnick, Eati Basal, Surendra Dasari, James P. Fryer, Shannon R. Hinson, Joseph Laporta, Amy Espinal, Dennis Fitzgerald, Carolina Garcia, Anna E. Morenkova, Paola Pergami, Anna Shah, Andrew Knight, Reghann LaFrance Corey, Vanda A. Lennon, Anastasia Zekeridou, Sean J. Pittock, Divyanshu Dubey, Andrew McKeon   +22 more
wiley   +1 more source

An overview of the European standard clinical practice recommendations for choroid plexus tumours

EJC Paediatric Oncology
Choroid plexus tumours (CPT) are rare epithelial brain tumours that primarily affect very young children. They can be classified as benign choroid plexus papilloma (CPP, WHO grade 1), intermediate grade atypical choroid plexus papilloma (aCPP, WHO grade ...
David King, Brigitte Bison, Ofelia Cruz, Claudia C. Faria, Iwona Filipek, Jonathan L. Finlay, Miklós Garami, Uwe R. Kordes, Ulrike Löbel, Jilly Maclean, Torben Stamm Mikkelsen, Denise Obrecht-Sturm, Guirish Solanki, Christian Thomas, Beate Timmerman, Michal Zapotocky, Jenny Adamski   +16 more
doaj   +1 more source

Safety and Efficacy of Anticoagulation Therapy in Paediatric Patients With Solid Tumours or Lymphomas at Risk of Thrombocytopenia: A Retrospective Study

Pediatric Blood &Cancer, Volume 73, Issue 2, February 2026.
ABSTRACT Background Patients with solid tumours or lymphomas have an increased risk of thromboembolism (TE) and thrombocytopenia. Evidence‐based strategies for anticoagulation therapy (ACT) for patients with thrombocytopenia are limited. We examined the impact of thrombocytopenia on ACT administration and bleeding incidence in children with solid ...
Andrés Felipe Fajardo, Katherine Talpin, Bishal Harry, Uma H. Athale, Anthony K. C. Chan, Mihir D. Bhatt   +5 more
wiley   +1 more source