Results 71 to 80 of about 627,049 (208)

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, Volume 73, Issue 7, July 2026.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Tumor‐type–specific expression of TTF‐1 in primary central nervous system tumors classified by the 2021 WHO criteria

The Journal of Pathology: Clinical Research, Volume 12, Issue 4, July 2026.
Abstract Thyroid transcription factor‐1 (TTF‐1) is a widely used immunohistochemical marker for tumors of thyroid and pulmonary origin; however, its expression profile and diagnostic relevance in primary central nervous system (CNS) tumors remain incompletely characterized, particularly following the revisions in the 2021 WHO Classification of CNS ...
Lu Xu, Hong‐Jiu Ren, Jian Gu, Bing‐Wen Shan, Tong Ren, Chu‐Hang Liu, Chun‐Xian Cai, Xiao‐Yu Zhang, Juan‐Han Yu   +8 more
wiley   +1 more source

Choroid plexus adenoma in a child: expanding the clinical and pathological spectrum

, 2018
Primary choroid plexus tumors encompass a variety of tumors, with choroid plexus papilloma and carcinoma being the most common. Also in the differential diagnosis is the rare benign choroid plexus adenoma.
Jeffrey D. Goldstein, Alexandra D. Beier, Nicole Prendergast   +2 more
core   +1 more source

"Compensated hyperosmolarity" of cerebrospinal fluid and the development of hydrocephalus [PDF]

, 2013
Acute osmolar loading of cerebrospinal fluid within one lateral ventricle of dogs was examined as a cause of water extraction from the bloodstream and an increase in intracranial pressure.
Vladić, Anton, Klarica, Marijan, Miše, Branko, Radoš, Milan, Orešković, Darko   +4 more
core   +1 more source

Differentiating the Clinical and Variant Spectrum of Hardikar Syndrome From Other MED12 ‐Related Developmental Disorders

American Journal of Medical Genetics Part A, Volume 200, Issue 7, Page 1619-1650, July 2026.
ABSTRACT The rare X‐linked female‐restricted Hardikar syndrome (HDKR, OMIM # 301068) is characterized by multiple congenital anomalies including orofacial clefts, gastrointestinal, genitourinary, and cardiac anomalies, but cognitive and neurobehavioral development is rarely impaired.
Tinne Warmoeskerken, Miel Theunis, Kris Van den Bogaert, Koenraad Devriendt, Jeroen Breckpot   +4 more
wiley   +1 more source

Immunohistochemical analysis of CDX2 expression in normal choroid plexus epithelium and choroid plexus tumors [PDF]

, 2009
Background: The Wnt and BMP signaling pathways are involved in the morphogenesis of both gastrointestinal and choroid plexus epithelium. In the intestine, Wnt signaling represses the expression of the tumor suppressor gene CDX2 via SOX9, a ...
Mugler, M., Beschorner, R., Meyermann, R., Schittenhelm, J., Mittelbronn, M.   +4 more
core  

Rare primary central nervous system tumors

Rare Tumors, 2014
There are close to 70,000 new cases of primary central nervous system tumors diagnosed annually in the United States. Meningiomas, gliomas, nerve sheath tumors and pituitary tumors account for 85% of them.
Charlotte Dai Kubicky, Arjun Sahgal, Eric L. Chang, Simon S. Lo   +3 more
doaj   +1 more source

Fecal Proteomics Suggest Potential Biomarkers for Non‐Alcoholic Fatty Liver Disease and Steatohepatitis

PROTEOMICS – Clinical Applications, Volume 20, Issue 4, July 2026.
ABSTRACT Background and aims Non‐alcoholic Fatty Liver Disease (NAFLD) affects about a quarter of the world's population. Liver biopsy remains the gold standard for diagnosing the progressive form of NAFLD called Non‐alcoholic Steatohepatitis (NASH) but it is invasive, prone to sampling errors and observer variability, and impractical for widespread ...
Anna Negroni, Luisa Pieroni, Noemi Fiaschini, Francesca Palone, Mariateresa Mancuso, Roberta Vitali   +5 more
wiley   +1 more source

Choroid plexus metastasis from carcinoma of the bladder: A case report

, 2004
Metastatic tumours in the choroid plexus are generally considered to be very rare. We report a case of bladder carcinoma metastasizing to the choroid plexus of the trigone of the lateral ventricle.
Tuna M., Göçer A.I., Boyar B., Erman T.   +3 more
core   +1 more source

Comprehensive multiomics analysis reveals distinct differences between pediatric choroid plexus papilloma and carcinoma

Acta Neuropathologica Communications
Choroid plexus tumors (CPTs) are intraventricular tumors derived from the choroid plexus epithelium and occur frequently in children. The aim of this study was to investigate the genomic and epigenomic characteristics of CPT and identify the differences ...
Yeonsong Choi, Seung Ah Choi, Eun Jung Koh, Ilsun Yun, Suhyun Park, Sungwon Jeon, Yeonkyung Kim, Sangbeen Park, Donggeon Woo, Ji Hoon Phi, Sung-Hye Park, Dong-Seok Kim, Se Hoon Kim, Jung Won Choi, Ji Won Lee, Tae-Young Jung, Jong Bhak, Semin Lee, Seung-Ki Kim   +18 more
doaj   +1 more source