Amfenac increases the radiosensitivity of uveal melanoma cell lines [PDF]
Purpose To evaluate the proliferation rates of five human uveal melanoma (UM) cell lines after treatment with amfenac, a cyclooxygenase (COX)-2 inhibitor, and subsequent radiation exposure.Methods Five human UM cell lines (92.1, SP6.5, MKT-BR, OCM-1, and
A Figueiredo +42 more
core +2 more sources
Role of Radiotherapy in Management of Choroidal Melanoma: A Review
Choroidal melanoma is the most common primary malignant intraocular tumour. Traditional management of choroidal melanoma is enucleation and local resection. Radiotherapy is emerging as an alternative to surgery, salvaging the vision of the patient.
Shraddha Puranik +2 more
doaj +1 more source
Prognostic factors of liver metastases from uveal melanoma [PDF]
Objectives: This study was designed to assess survival and identify prognostic factors for liver metastases diagnosed by systematic screening in uveal melanoma patients. Methods: Among 602 consecutive patients treated over 10 years for uveal melanoma and
Baillif, Stéphanie +5 more
core
Chromosomal Gains and Losses in Uveal Melanomas Detected by Comparative Genomic Hybridization [PDF]
Eleven uveal melanomas were analyzed using comparative genomic hybridization (CGH). The most abundant genetic changes were loss of chromosome 3, overrepresentation of 6p, loss of 6q, and multiplication of 8q.
Becher, Reinhard +7 more
core
Prognostic factors of choroidal melanoma in Slovenia, 1986–2008
Choroidal melanoma is the most common primary malignancy of the eye, which frequently metastasizes. The Cancer Registry of Slovenia reported the incidence of choroid melanoma from 1983 to 2009 as stable, at 7.8 cases/million for men and 7.4/million for ...
Jancar Boris +5 more
doaj +1 more source
Delayed Distant Recurrence of a Uveal Melanoma 4 Decades after Enucleation
Introduction: This report presents a case of an exceptionally delayed distant recurrence of a choroidal melanoma, occurring 4 decades after the enucleation of the affected eye.
Nils A. Eide +4 more
doaj +1 more source
Treated Choroidal Melanoma with Late Metastases to the Contralateral Orbit
Choroidal melanoma is the commonest adult primary intraocular tumour, 1 and usual sites of secondary spread are to liver, bone and lung. Although delayed recurrence of ipsilateral orbital melanoma is well documented, metastasis to the contralateral orbit
Sonia George +4 more
doaj +1 more source
Cellular radiosensitivity of primary and metastatic human uveal melanoma cell lines [PDF]
PURPOSE: To investigate the radiosensitivity of uveal melanoma cell lines by a clonogenic survival assay, to improve the efficiency of the radiation regimen. METHODS: Four primary and four metastatic human uveal melanoma cell lines were
Aardweg, G.J.M.J. (Gerard) van den +4 more
core
PRIMARY CHOROIDAL MALIGNANT LYMPHOMA:REPORT OF A CASE AND REVIEW OF LITERATURE [PDF]
Non-Hodgkin lymphoma (NHL) is one of the masquerade syndromes of malignant melanoma that can occur with two main patterns of presentations in the eye: metastatic involvement of uveal tract, and primary involvement of retina. We report ophthalmic, imaging
F. Asadi Amoli +2 more
doaj +2 more sources
Bilateral Choroidal Metastases as Presentation of Dissemination of Cutaneous Malignant Melanoma
Case Report. A 47-year-old man presented with blurred vision in the right eye. Ophthalmoscopic examination showed several placoid, pigmented lesions in the posterior pole and midperiphery of the retina of both eyes. Results.
S. Fernandez-Perez +4 more
doaj +1 more source

