Results 1 to 10 of about 19,736 (150)
Insights into Imaging, 2021 Uveal melanoma is a malignant neoplasm that derives from pigmented melanocytes of the uvea and involves, in order of decreasing prevalence, the choroid, ciliary body and iris.
Pietro Valerio Foti +16 more
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Immunohistochemical Expression of ABCB5 as a Potential Prognostic Factor in Uveal Melanoma
Applied Sciences, 2019 Uveal melanoma represents the most common primary intraocular malignancy in adults; it may arise in any part of the uveal tract, with choroid and ciliary bodies being the most frequent sites of disease.
Giuseppe Broggi +7 more
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The clinical and histopathological features of patients with both uveal and cutaneous melanoma
The Pan-American Journal of Ophthalmology, 2020 Introduction: It is unusual to have uveal and cutaneous melanoma in the same patient. It is challenging to differentiate between primary uveal melanoma (UM) and melanoma metastatic to the uvea.
Anelise Savaris Dias +7 more
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Hemorrhagic choroidal detachment as the presenting sign of uveal melanoma
American Journal of Ophthalmology Case Reports, 2021 Purpose: To describe two cases of medium-sized uveal melanoma presenting with hemorrhagic choroidal detachments. Observations: The first case is a 39-year-old man who presented with choroidal hemorrhage and angle closure glaucoma. The second case is a 42-
Yewlin E. Chee +8 more
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Necrotic uveal melanoma presenting as orbital cellulitis with intraocular hemorrhage: A case report
American Journal of Ophthalmology Case Reports, 2019 Purpose: To report a case of necrotic uveal melanoma presenting as orbital cellulitis with an intraocular hemorrhage. Observations: A 61 year-old non-verbal male presented with a two-week history of right eyelid swelling and erythema unresponsive to ...
Alexa L. Li +4 more
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BAP1 methylation: a prognostic marker of uveal melanoma metastasis
npj Precision Oncology, 2021 Uveal melanoma, the most common intraocular primary cancer in adults, is characterized by striking variability in metastatic tendencies. BAP1 deletion in the primary tumor is associated with uveal melanoma metastasis, but it cannot always be resolved by ...
Mathieu F. Bakhoum +3 more
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Mda-9/syntenin is expressed in uveal melanoma and correlates with metastatic progression. [PDF]
PLoS ONE, 2012 Uveal melanoma is an aggressive cancer that metastasizes to the liver in about half of the patients, with a high lethality rate. Identification of patients at high risk of metastases may provide indication for a frequent follow-up for early detection of ...
Rosaria Gangemi +18 more
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Uveal melanoma incidentally diagnosed with neuroimaging, a case series of 3 patients
Radiology Case Reports, 2022 Uveal melanoma is the most common primary intraocular malignancy and can occur in the choroid, the ciliary body, or the iris. It is most often diagnosed based on clinical examination by an ophthalmologist. Nearly all patients present with visual symptoms.
Mai Tsukikawa, MD +4 more
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Uveal melanoma: Estimating prognosis
Indian Journal of Ophthalmology, 2015 Uveal melanoma is the most common primary malignant tumor of the eye in adults, predominantly found in Caucasians. Local tumor control of uveal melanoma is excellent, yet this malignancy is associated with relatively high mortality secondary to ...
Swathi Kaliki +2 more
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Regulatory harmonization: Evolution, globalization and future directions
British Journal of Clinical Pharmacology, EarlyView.Regulatory harmonization has become an increasingly important and accepted approach to streamline regulatory review processes and expedite access to safe, effective and high‐quality medicines globally. This review explores the evolution and current status of regulatory harmonization, convergence and reliance initiatives.
Orin Chisholm +2 more
wiley +1 more source