Results 21 to 30 of about 195,013 (218)
PRAME predicting outcome in uveal melanoma [PDF]
J Pathol Clin ResAbstract Uveal melanoma (UM) is the most common primary intra‐ocular malignancy in adults and carries a high risk of metastatic disease, affecting approximately 50% of patients despite advances in local tumour control. PRAME (PReferentially expressed Antigen in MElanoma) has emerged as a marker for metastatic risk; however, evidence is largely derived ...
Owens S +8 more
europepmc +2 more sources
Proton beam radiotherapy in the management of uveal melanoma: clinical experience in Scotland [PDF]
, 2008 <p>Aim: To evaluate proton-beam radiotherapy (PBRT) in the management of uveal melanoma in Scotland.</p> <p>Methods: A retrospective review was undertaken on all patients receiving PBRT for uveal melanoma (1994–2005).
McConnachie, A. +9 more
core +1 more source
Modelling uveal melanoma [PDF]
British Journal of Ophthalmology, 1999 There has been no consistent pattern reported on how mortality for uveal melanoma varies with age. This information can be useful to model the complexity of the disease. The authors have examined ocular cancer trends, as an indirect measure for uveal melanoma mortality, to see how rates vary with age and to compare the results with their other studies ...
A J, Foss +3 more
openaire +2 more sources
Biology of advanced uveal melanoma and next steps for clinical therapeutics [PDF]
, 2014 Uveal melanoma is the most common intraocular malignancy although it is a rare subset of all melanomas. Uveal melanoma has distinct biology relative to cutaneous melanoma, with widely divergent patient outcomes.
Gutkind, JS +17 more
core +3 more sources
Ocular Oncology and Pathology, 2020 <b><i>Introduction:</i></b> Multiple uveal melanoma is a rare occurrence and includes bilateral melanoma, unilateral multiple/multifocal melanoma, or melanoma with metastasis to the ipsilateral or contralateral eye. <b><i>Methods:</i></b> A chart review of patients diagnosed with uveal melanoma between ...
Wajiha J. Kheir +2 more
openaire +2 more sources
The diagnosis of metastatic uveal melanoma. What has changed during 10 years?
Alʹmanah Kliničeskoj Mediciny, 2020 Uveal melanoma is the most common intraocular malignancy. Despite significant progress in the treatment of the primary tumor, uveal melanoma continues to be the most aggressive tumor due to its high potential for hematogenous metastatic spread.
E. E. Grishina +2 more
doaj +1 more source
Discover Oncology, 2022 Background The incidence of uveal melanoma increases with latitude. In this study, we examine the importance of latitude for uveal melanoma prognosis. Methods All uveal melanoma patients born in Sweden between 1947 and 1990 were included (n = 745).
Gustav Stålhammar +2 more
doaj +1 more source
Inflammation in uveal melanoma [PDF]
Eye, 2012 Leukocytic infiltration is a common feature of human cancers, including those that develop in immunoprivileged sites, such as the eye. The infiltration of myeloid and T cells into tumours is part of the host response against cancer. In uveal melanoma, high densities of immune cells seem to be involved in tumour progression, as they are associated with ...
Bronkhorst, I.H.G., Jager, M.J.
openaire +4 more sources
Uveal Melanoma in Ireland [PDF]
Ocular Oncology and Pathology, 2018 <b><i>Purpose:</i></b> To report the clinical features and epidemiology of uveal melanoma in Ireland. <b><i>Methods:</i></b> This was an observational study of 253 patients with a new diagnosis of uveal melanoma between June 2010 and December 2015.
Caroline, Baily +8 more
openaire +2 more sources
MiR-144 Inhibits Uveal Melanoma Cell Proliferation and Invasion by Regulating c-Met Expression. [PDF]
PLoS ONE, 2015 MicroRNAs (miRNAs) are a group endogenous small non-coding RNAs that inhibit protein translation through binding to specific target mRNAs. Recent studies have demonstrated that miRNAs are implicated in the development of cancer.
Lei Sun +5 more
doaj +1 more source