Local treatment failure after globe-conserving therapy for choroidal melanoma. [PDF]
Local treatment failure after globe-conserving therapy for choroidal melanoma is a surgical complication with significant morbidity to the vision and eye. Few reports in the literature have addressed this complication exclusively.
Chang, Melinda Y, McCannel, Tara A
core +1 more source
Differences and Similarities in Epidemiology and Risk Factors for Cutaneous and Uveal Melanoma
Both cutaneous melanoma (CM) and uveal melanoma (UM) represent important causes of morbidity and mortality. In this review, we evaluate the available knowledge on the differences and similarities between cutaneous melanoma and uveal melanoma, focusing on
Daciana Elena Brănișteanu +10 more
doaj +1 more source
The reporting of uveal melanoma cases to the cancer registry in North Carolina
ObjectiveTo ascertain the completeness of reporting of uveal melanoma cases in North Carolina to the state’s cancer registry.MethodsThis was a retrospective chart review performed at a single institution analyzing the completeness of information reported
Kathleen G. Gordon +3 more
doaj +1 more source
Long Overall Survival After Dendritic Cell Vaccination in Metastatic Uveal Melanoma Patients [PDF]
Purpose: To assess the safety and efficacy of dendritic cell vaccination in metastatic uveal melanoma. Design: Interventional case series. Methods: We analyzed 14 patients with metastatic uveal melanoma treated with dendritic cell vaccination.
Aarntzen, E.H.J.G. (Erik) +10 more
core +1 more source
Ladarixin, a dual CXCR1/2 inhibitor, attenuates experimental melanomas harboring different molecular defects by affecting malignant cells and tumor microenvironment. [PDF]
CXCR1 and CXCR2 chemokine receptors and their ligands (CXCL1/2/3/7/8) play an important role in tumor progression. Tested to date CXCR1/2 antagonists and chemokine-targeted antibodies were reported to affect malignant cells in vitro and in animal models.
Alexeev, Vitali +10 more
core +2 more sources
Assessment of the effect of iris colour and having children on 5-year risk of death after diagnosis of uveal melanoma: a follow-up study [PDF]
BACKGROUND: To examine the all-cause mortality and uveal melanoma specific mortality among newly diagnosed uveal melanoma patients after five years. Furthermore, we assess of the effect of iris colour and having children on 5-year risk of death after ...
Andrea Schmidt-Pokrzywniak +5 more
core +2 more sources
Uveal melanoma is a malignant neoplasm that derives from pigmented melanocytes of the uvea and involves, in order of decreasing prevalence, the choroid, ciliary body and iris.
Pietro Valerio Foti +16 more
doaj +1 more source
Paracrine Effect of NRG1 and HGF Drives Resistance to MEK Inhibitors in Metastatic Uveal Melanoma. [PDF]
Uveal melanoma patients with metastatic disease usually die within one year, emphasizing an urgent need to develop new treatment strategies for this cancer.
Aplin, Andrew E. +6 more
core +2 more sources
Immunohistochemical Expression of ABCB5 as a Potential Prognostic Factor in Uveal Melanoma
Uveal melanoma represents the most common primary intraocular malignancy in adults; it may arise in any part of the uveal tract, with choroid and ciliary bodies being the most frequent sites of disease.
Giuseppe Broggi +7 more
doaj +1 more source
Hemorrhagic choroidal detachment as the presenting sign of uveal melanoma
Purpose: To describe two cases of medium-sized uveal melanoma presenting with hemorrhagic choroidal detachments. Observations: The first case is a 39-year-old man who presented with choroidal hemorrhage and angle closure glaucoma. The second case is a 42-
Yewlin E. Chee +8 more
doaj +1 more source

