Results 51 to 60 of about 294,312 (244)
Cancers, 2019 Uveal melanoma (UM) is among the best characterized solid tumors [...]
openaire +2 more sources
Uveal melanoma: towards a molecular understanding.
Progress in retinal and eye research, 2020 Uveal melanoma is an aggressive malignancy that originates from melanocytes in the eye. Even if the primary tumor has been successfully treated with radiation or surgery, up to half of all UM patients will eventually develop metastatic disease.
Kyra N. Smit +3 more
semanticscholar +1 more source
Posterior uveal melanoma incidence and survival by AJCC tumour size in a 70‐year nationwide cohort
Acta ophthalmologica, 2021 While early treatment of posterior uveal melanoma can save the eye, the effect of early treatment on survival remains unknown. Therefore, we aimed to determine whether the tumour size at diagnosis has changed over time, and if this has affected survival ...
Isabel G Smidt-Nielsen +4 more
semanticscholar +1 more source
The reporting of uveal melanoma cases to the cancer registry in North Carolina
Frontiers in Oncology, 2022 ObjectiveTo ascertain the completeness of reporting of uveal melanoma cases in North Carolina to the state’s cancer registry.MethodsThis was a retrospective chart review performed at a single institution analyzing the completeness of information reported
Kathleen G. Gordon +3 more
doaj +1 more source
The Role of HGF/MET Signaling in Metastatic Uveal Melanoma
Cancers, 2021 Simple Summary Hepatocyte growth factor (HGF)/mesenchymal-epithelial transition factor (MET) signaling plays an important role in the metastatic formation and therapeutic resistance to uveal melanoma.
R. Tanaka +3 more
semanticscholar +1 more source
Uveal melanoma immunogenomics predict immunotherapy resistance and susceptibility
Nature CommunicationsImmune checkpoint inhibition has shown success in treating metastatic cutaneous melanoma but has limited efficacy against metastatic uveal melanoma, a rare variant arising from the immune privileged eye.
Shravan Leonard-Murali +19 more
semanticscholar +1 more source
The long non-coding RNA SAMMSON is essential for uveal melanoma cell survival
bioRxiv, 2021 Long non-coding RNAs (lncRNAs) can exhibit cell-type and cancer-type specific expression profiles, making them highly attractive as therapeutic targets. Pan-cancer RNA sequencing data revealed broad expression of the SAMMSON lncRNA in uveal melanoma (UM),
S. Dewaele +18 more
semanticscholar +1 more source
Genetic Landscape and Emerging Therapies in Uveal Melanoma
Cancers, 2021 Simple Summary Uveal melanoma is the most common primary intraocular malignancy in adults. Unfortunately, metastasis develops in up to 50% of cases and outcomes are poor for these patients.
R. Seedor, M. Orloff, Takami Sato
semanticscholar +1 more source
Immunohistochemical Expression of ABCB5 as a Potential Prognostic Factor in Uveal Melanoma
Applied Sciences, 2019 Uveal melanoma represents the most common primary intraocular malignancy in adults; it may arise in any part of the uveal tract, with choroid and ciliary bodies being the most frequent sites of disease.
Giuseppe Broggi +7 more
doaj +1 more source
The clinical and histopathological features of patients with both uveal and cutaneous melanoma
The Pan-American Journal of Ophthalmology, 2020 Introduction: It is unusual to have uveal and cutaneous melanoma in the same patient. It is challenging to differentiate between primary uveal melanoma (UM) and melanoma metastatic to the uvea.
Anelise Savaris Dias +7 more
doaj +1 more source