Results 51 to 60 of about 16,711 (227)
Systemic Surveillance Guidelines for Uveal Melanoma: A Systematic Review
ABSTRACT Background Uveal melanoma (UM) is the most common primary intraocular tumour. Despite effective local therapies, UM has a high risk of metastatic recurrence, most frequently to the liver. A significant proportion of patients treated definitively for primary UM eventually experience metastatic disease. Systemic surveillance to detect recurrence
Farzana Y. Zaman +6 more
wiley +1 more source
Survival impact of second primary cutaneous and non‐cutaneous melanoma in melanoma survivors
In this US population‐based cohort study, melanoma survivors diagnosed with regional/distant‐stage SPCM or SPNCM had worse survival compared to those with a single melanoma. Abstract Background Melanoma survivors have a high risk of developing second primary neoplasms, both cutaneous melanoma (SPCM) and non‐cutaneous melanoma (SPNCM), but little is ...
Jingjing Xie +3 more
wiley +1 more source
Outcome of ATP-based tumor chemosensitivity assay directed chemotherapy in heavily pre-treated recurrent ovarian carcinoma [PDF]
BACKGROUND: We wished to evaluate the clinical response following ATP-Tumor Chemosensitivity Assay (ATP-TCA) directed salvage chemotherapy in a series of UK patients with advanced ovarian cancer. The results are compared with that of a similar assay used
A du Bois +59 more
core +4 more sources
ABSTRACT Background Uveal melanoma is the most common malignant primary intraocular tumor in adults, associated with high mortality. Pediatric uveal melanoma generally has a more favorable course. However, when metastasis occurs, therapeutic options are limited.
Pia Tüller +18 more
wiley +1 more source
Tibial Periosteum For The Surgical Perforation [PDF]
Purpose: Report a successful case of scleral perforation repair, refractive to treatment with bank-scleral graft, using pretibial periosteum graft patch.
Mateo A +5 more
core +1 more source
The Potential of Phytochemicals to Overcome Multidrug Resistance in Metastatic Melanoma
ABSTRACT Metastatic melanoma is the most lethal form of skin cancer, accounting for most skin cancer‐related deaths. Immunotherapies and targeted therapies have improved overall and progression‐free survival rates in metastatic melanoma patients. The effectiveness of these therapies decreases due to multidrug resistance (MDR).
Jacqueline Maphutha +4 more
wiley +1 more source
Beyond Treatment: The Strategy of Nonintervention in Choroidal Hemangioma
ABSTRACT The circumscribed choroidal hemangioma (CCH) is a benign congenital eye tumor whose etiology is not clear. A 41‐year‐old female patient came with a 2‐year history of slowly progressive deteriorating vision in her right eye. In the left eye, the best‐corrected visual acuity (BCVA) was 6/6, and counting fingers at 1 m in the right eye.
Humdan Khan +8 more
wiley +1 more source
Background To describe the superiority of ocular ultrasound in the diagnostic management of extrascleral extension in choroidal melanoma. Case presentation We present a case of a 94-year-old male with choroidal melanoma of the right eye imaged with MRI ...
Bradley H. Jacobsen +2 more
doaj +1 more source
Genome-wide screening of mouse knockouts reveals novel genes required for normal integumentary and oculocutaneous structure and function. [PDF]
Oculocutaneous syndromes are often due to mutations in single genes. In some cases, mouse models for these diseases exist in spontaneously occurring mutations, or in mice resulting from forward mutatagenesis screens.
Adissu, Hibret +15 more
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