Results 111 to 120 of about 101,649 (294)

Assistance of Artificial Intelligence in Diagnosis of Vitreoretinal Lymphoma on Optical Coherence Tomography

Advanced Intelligent Systems, Volume 7, Issue 4, April 2025.
The proposed artificial intelligence model, cross‐subject meta‐transfer learning, enables the automatic detection of vitreoretinal lymphoma (VRL) on optical coherence tomography images among 16 retinal diseases and conditions. This study provides an innovative solution to assist in the VRL diagnosis in real‐world clinical implementation, showing ...
Aidi Lin, Yuanyuan Peng, Tian Lin, Jun Dai, Jizhu Li, Tingkun Shi, Xixuan Ke, Xulong Liao, Danqi Fang, Man Chen, Huiyu Liang, Shirong Chen, Honghe Xia, Jingtao Wang, Zehua Jiang, Tao Li, Dan Liang, Shanshan Yu, Jing Luo, Ling Gao, Dawei Sun, Yih Chung Tham, Xinjian Chen, Haoyu Chen   +23 more
wiley   +1 more source

Retinal and choroidal angiogenesis: a review of new targets

International Journal of Retina and Vitreous, 2017
Retinal and choroidal neovascularization are a major cause of significant visual impairment, worldwide. Understanding the various factors involved in the accompanying physiopathology is vital for development of novel treatments, and most important, for ...
Thiago Cabral, Luiz Guilherme M. Mello, Luiz H. Lima, Júlia Polido, Caio V. Regatieri, Rubens Belfort, Vinit B. Mahajan   +6 more
doaj   +1 more source

Choroidal image analysis for OCT image sequences with applications in systemic health [PDF]

The choroid, a highly vascular layer behind the retina, is an extension of the central nervous system and has parallels with the renal cortex, with blood flow far exceeding that of the brain and kidney. Thus, there has been growing interest of choroidal blood flow reflecting physiological status of systemic disease.
arxiv   +1 more source

Noninvasive Detection of Chorioretinal Hypoxia via Poly(lactic‐co‐glycolic acid) Nanoparticles Embedded with Purely Organic Phosphors

Advanced NanoBiomed Research, Volume 5, Issue 4, April 2025.
A flexible lipid–polymer hybrid core–shell nanoparticle system that exhibits organic room‐temperature phosphorescence nanoprobes for real‐time optical imaging of ischemia‐induced tissue hypoxia. These biocompatible nanoprobes are highly sensitive to oxygen quenching and can effectively identify chorioretinal tissue hypoxia in clinically relevant living
Jung‐Moo Heo, Van Phuc Nguyen, Mi Zheng, Jihyun Park, Yannis M. Paulus, Jinsang Kim   +5 more
wiley   +1 more source

BioNet: Infusing Biomarker Prior into Global-to-Local Network for Choroid Segmentation in Optical Coherence Tomography Images [PDF]

arXiv, 2019
Choroid is the vascular layer of the eye, which is directly related to the incidence and severity of many ocular diseases. Optical Coherence Tomography (OCT) is capable of imaging both the cross-sectional view of retina and choroid, but the segmentation of the choroid region is challenging because of the fuzzy choroid-sclera interface (CSI).
arxiv  

Atypical choroidal neovascular membrane

American Journal of Ophthalmology Case Reports
To report the course of atypical choroidal neovascularization (CNV) in a middle-aged woman experiencing sudden vision loss.A middle-aged female presented with sudden onset vision loss. Following in depth investigations an initial diagnosis of presumed idiopathic CNV was made in her right eye.
Kimia Rezaei, Shaden H. Yassin, Henry Ferreyra, Shyamanga Borooah   +3 more
openaire   +3 more sources

Escherichia coli in the production of biopharmaceuticals

Biotechnology and Applied Biochemistry, Volume 72, Issue 2, Page 528-541, April 2025.
Abstract Escherichia coli has shouldered a massive workload with the discovery of recombinant DNA technology. A new era began in the biopharmaceutical industry with the production of insulin, the first recombinant protein, in E. coli and its use in treating diabetes. After insulin, many biopharmaceuticals produced from E. coli have been approved by the
İbrahim İncir, Özlem Kaplan
wiley   +1 more source

Geographic Atrophy and Choroidal Neovascularization in the Same Eye: A Review

Ophthalmic Research, 2016
Geographic atrophy (GA) and choroidal neovascularization (CNV), the two late forms of age-related macular degeneration, are generally considered two distinct entities.
P. Kaszubski, T. Ben Ami, C. Saade, R. Theodore Smith   +3 more
semanticscholar   +1 more source

Inflammatory choroidal neovascularization in Indian eyes: Etiology, clinical features, and outcomes to anti-vascular endothelial growth factor

Indian Journal of Ophthalmology, 2017
Background and Objectives: The aim was to study the clinical profile of inflammatory choroidal neovascularization (CNV) and its treatment response to intravitreal bevacizumab or ranibizumab on pro re nata (PRN) basis in Indian eyes. Materials and Methods:
Rupak Roy, Kumar Saurabh, Aditya Bansal, Amitabh Kumar, Anindya Kishore Majumdar, Swakshyar Saumya Paul   +5 more
doaj   +1 more source

circSIRT2/miR‐542‐3p/VASH1 axis regulates endothelial‐to‐mesenchymal transition (EndMT) in subretinal fibrosis in age‐related macular degeneration models

Aging Cell, Volume 24, Issue 4, April 2025.
circSIRT2 inhibited SRF by binding miR‐542‐3p, which stimulated the VASH1 expression and subsequently suppressed EndMT. The circSIRT2/miR‐542‐3p/VASH1 axis may serve as a promising therapeutic target for SRF in nAMD. Abstract Neovascular age‐related macular degeneration (nAMD), characterized by choroidal neovascularization (CNV), is one of the leading ...
Min Zhang, Jiali Wu, Yimin Wang, Yidong Wu, Xiaoling Wan, Mei Jiang, Qiyu Bo, Jieqiong Chen, Xiaodong Sun   +8 more
wiley   +1 more source