Results 21 to 30 of about 21,167 (230)

Annexin A2 Egress during Calcium-Regulated Exocytosis in Neuroendocrine Cells

open access: yesCells, 2020
Annexin A2 (AnxA2) is a calcium- and lipid-binding protein involved in neuroendocrine secretion where it participates in the formation and/or stabilization of lipid micro-domains required for structural and spatial organization of the exocytotic ...
Marion Gabel   +7 more
doaj   +1 more source

Platelet granule exocytosis: A comparison with chromaffin cells

open access: yesFrontiers in Endocrinology, 2013
The rapid secretion of bioactive amines from chromaffin cells constitutes an important component of the fight or flight response of mammals to stress.
Jennifer eFitch-Tewfik   +1 more
doaj   +1 more source

The hemodynamically-regulated vascular microenvironment promotes migration of the steroidogenic tissue during its interaction with chromaffin cells in the zebrafish embryo. [PDF]

open access: yesPLoS ONE, 2014
BACKGROUND: While the endothelium-organ interaction is critical for regulating cellular behaviors during development and disease, the role of blood flow in these processes is only partially understood.
Chih-Wei Chou   +3 more
doaj   +1 more source

Purification of Adrenal Chromaffin Cells Increases Antinociceptive Efficacy of Xenotransplants without Immunosuppression

open access: yesCell Transplantation, 1999
We have found that immunosuppression is necessary for the survival of xenogeneic adrenal medullary transplants. Because chromaffin cells are essentially nonimmunogenic, it is likely that the highly immunogenic “passenger” cells in the transplant ...
P. Michalewicz   +4 more
doaj   +1 more source

Alterations of the Sympathoadrenal Axis Related to the Development of Alzheimer’s Disease in the 3xTg Mouse Model

open access: yesBiology, 2022
Alzheimer’s disease (AD), the most common form of dementia, is becoming a global health problem and public health priority. In the advanced stages of AD, besides the initial cognitive symptoms, behavioral problems, particularly agitation and ...
Alicia Muñoz-Montero   +4 more
doaj   +1 more source

Chronic Ultraviolet Irradiation to the Skin Dysregulates Adrenal Medulla and Dopamine Metabolism In Vivo

open access: yesAntioxidants, 2021
Ultraviolet (UV) radiation has a strong biological effect on skin biology, and it switches on adaptive mechanisms to maintain homeostasis in organs such as the skin, adrenal glands, and brain.
Hye-Sun Lim   +5 more
doaj   +1 more source

Schwann Cell Precursors Generate the Majority of Chromaffin Cells in Zuckerkandl Organ and Some Sympathetic Neurons in Paraganglia

open access: yesFrontiers in Molecular Neuroscience, 2019
In humans, neurosecretory chromaffin cells control a number of important bodily functions, including those related to stress response. Chromaffin cells appear as a distinct cell type at the beginning of midgestation and are the main cellular source of ...
Maria Eleni Kastriti   +19 more
doaj   +1 more source

Synaptotagmin-7 places dense-core vesicles at the cell membrane to promote Munc13-2- and Ca2+-dependent priming

open access: yeseLife, 2021
Synaptotagmins confer calcium-dependence to the exocytosis of secretory vesicles, but how coexpressed synaptotagmins interact remains unclear. We find that synaptotagmin-1 and synaptotagmin-7 when present alone act as standalone fast and slow Ca2 ...
Bassam Tawfik   +8 more
doaj   +1 more source

v-SNARE function in chromaffin cells [PDF]

open access: yesPflügers Archiv - European Journal of Physiology, 2017
Vesicle fusion is elementary for intracellular trafficking and release of signal molecules, thus providing the basis for diverse forms of intercellular communication like hormonal regulation or synaptic transmission. A detailed characterization of the mechanisms underlying exocytosis is key to understand how the nervous system integrates information ...
Dhara, Madhurima   +2 more
openaire   +2 more sources

GATA2 functions in adrenal chromaffin cells [PDF]

open access: yesGenes to Cells, 2020
AbstractCatecholamine synthesized in the sympathoadrenal system, including sympathetic neurons and adrenal chromaffin cells, is vital for cardiovascular homeostasis. It has been reported that GATA2, a zinc finger transcription factor, is expressed in murine sympathoadrenal progenitor cells.
Tomomi Watanabe‐Asaka   +4 more
openaire   +3 more sources

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