Results 11 to 20 of about 18,956 (172)

EdU-Based Step-by-Step Method for the Detection of Sister Chromatid Exchanges for Application in Plant Genotoxicity Assessment

open access: yesFrontiers in Plant Science, 2020
This study is an example of using 5-ethynyl-2′-deoxyuridine (EdU) for detecting sister chromatid exchanges (SCEs) at chromosomal level. Here we report a detailed protocol for differential labeling sister chromatids in barley (Hordeum vulgare, 2n = 14 ...
Jolanta Kwasniewska, Adrianna Bara
doaj   +1 more source

PIASgamma is required for faithful chromosome segregation in human cells. [PDF]

open access: yesPLoS ONE, 2006
BACKGROUND:The precision of the metaphase-anaphase transition ensures stable genetic inheritance. The spindle checkpoint blocks anaphase onset until the last chromosome biorients at metaphase plate, then the bonds between sister chromatids are removed ...
Laura A Díaz-Martínez   +6 more
doaj   +1 more source

Cohesin is required for meiotic spindle assembly independent of its role in cohesion in C. elegans.

open access: yesPLoS Genetics, 2022
Accurate chromosome segregation requires a cohesin-mediated physical attachment between chromosomes that are to be segregated apart, and a bipolar spindle with microtubule plus ends emanating from exactly two poles toward the paired chromosomes. We asked
Karen P McNally   +7 more
doaj   +1 more source

Mechanics of Sister Chromatids studied with a Polymer Model

open access: yesFrontiers in Physics, 2013
Sister chromatid cohesion denotes the phenomenon that sister chromatids are initially attached to each other in mitosis to guarantee the error-free distribution into the daughter cells.
Yang eZhang   +3 more
doaj   +1 more source

The cohesin subunit Rad21 is required for synaptonemal complex maintenance, but not sister chromatid cohesion, during Drosophila female meiosis. [PDF]

open access: yesPLoS Genetics, 2014
Replicated sister chromatids are held in close association from the time of their synthesis until their separation during the next mitosis. This association is mediated by the ring-shaped cohesin complex that appears to embrace the sister chromatids ...
Evelin Urban   +3 more
doaj   +1 more source

Sister Chromatid Cohesion [PDF]

open access: yesCold Spring Harbor Perspectives in Biology, 2012
During S phase, not only does DNA have to be replicated, but also newly synthesized DNA molecules have to be connected with each other. This sister chromatid cohesion is essential for the biorientation of chromosomes on the mitotic or meiotic spindle, and is thus an essential prerequisite for chromosome segregation.
Peters, J.-M. and Nishiyama, T.
openaire   +2 more sources

Helping chromosomes and chromatids stay on track

open access: yeseLife, 2012
The prevention of premature interactions between microtubules and kinetochores is essential to ensuring that meiosis produces gametes with the correct number of chromosomes.
Soni Lacefield
doaj   +1 more source

DNA damage in the kidney tissue cells of the fish Rhamdia quelen after trophic contamination with aluminum sulfate

open access: yesGenetics and Molecular Biology, 2015
Even though aluminum is the third most common element present in the earth's crust, information regarding its toxicity remains scarce. It is known that in certain cases, aluminum is neurotoxic, but its effect in other tissues is unknown.
Tatiane Klingelfus   +3 more
doaj   +1 more source

A single cohesin complex performs mitotic and meiotic functions in the protist tetrahymena.

open access: yesPLoS Genetics, 2013
The cohesion of sister chromatids in the interval between chromosome replication and anaphase is important for preventing the precocious separation, and hence nondisjunction, of chromatids.
Rachel A Howard-Till   +3 more
doaj   +1 more source

Pch2 prevents Mec1/Tel1-mediated Hop1 phosphorylation occurring independently of Red1 in budding yeast meiosis. [PDF]

open access: yesPLoS ONE, 2014
A prominent feature of meiosis in most sexually reproducing organisms is interhomolog recombination whereby a significant fraction of the programmed meiotic double-strand breaks are repaired using intact homologous non-sister chromatids rather than ...
Yu-Hui Lo   +2 more
doaj   +1 more source

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