Results 181 to 190 of about 201,890 (354)

Chromatin remodeler Brahma safeguards canalization in cardiac mesoderm differentiation [PDF]

open access: green, 2020
Swetansu K. Hota   +8 more
openalex   +1 more source

Single‐Nucleus Multi‐Omics Reveals Hypoxia‐Driven Angiogenic Programs and Their Epigenetic Control in Sinonasal Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
Single‐nucleus multi‐omics profiling of sinonasal squamous cell carcinoma unveils a hypoxia‐driven angiogenic axis. A specific hypoxic tumor subpopulation orchestrates endothelial tip cell differentiation via epigenetically regulated ADM and VEGFA secretion.
Chaelin You   +12 more
wiley   +1 more source

Retinoic Acid Receptor α Fusion to PML Affects Its Transcriptional and Chromatin-Remodeling Properties

open access: green, 2003
Simona Segalla   +6 more
openalex   +2 more sources

Extravillous trophoblast cell lineage development is associated with active remodeling of the chromatin landscape [PDF]

open access: gold, 2023
Kaela M. Varberg   +17 more
openalex   +1 more source

Targeting the SOX9/TIMP1 Axis with iRGD‐Conjugated Nanoplatform Enhances Dendritic Cell Function and Photodynamic Immunotherapy in Gastric Cancer

open access: yesAdvanced Science, EarlyView.
This study identifies the SOX9/TIMP1 axis as a key regulator of immune evasion in gastric cancer. iRGD‐conjugated nanoparticles co‐delivering si‐SOX9, Ce6, and L‐Arg are developed to synergize with photodynamic therapy. The nanoplatform suppresses tumor growth, promotes dendritic cell maturation, and enhances CD8+ T‐cell activation, offering a ...
Banghua Zhong   +3 more
wiley   +1 more source

Temporal Stretch‐Induced Nuclear Mechanosensing Coordinates Early Chromatin Accessibility and Genome Protection

open access: yesAdvanced Science, EarlyView.
Cyclic stretching of fibroblasts triggers coordinated nuclear mechanosensing events, including calcium ion release, perinuclear actin assembly, emerin translocation, and H3K9me3 loss, increasing chromatin accessibility for specific genes related to mechanotransduction and repair.
Hye‐Won Shim   +10 more
wiley   +1 more source

Fibroblastic niches in action: CCL19 + reticular cells drive anti-tumor immunity in lung cancer

open access: yesSignal Transduction and Targeted Therapy
Alessandro Ianni   +2 more
doaj   +1 more source

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