Results 211 to 220 of about 201,890 (354)

Chromatin remodeling restrains oncogenic functions in prostate cancer. [PDF]

Nat Commun
Rosti V, Lembo G, Petrini C, Gorini F, Quadri R, Cordiglieri C, Mutarelli M, Salviato E, Casari E, Di Patrizio Soldateschi E, Montanari E, Albo G, Ripa F, Fasciani A, Crosti M, De Lorenzis E, Maggioni M, Vaira V, Vivo M, Ferrari F, Lanzuolo C.   +20 more
europepmc   +1 more source

Lipid‐Driven OLR1/FOXM1/FGF19 Axis Orchestrates Crosstalk in an Epithelial‐Fibroblast Positive Feedback Promoting Progesterone Resistance in Endometrial Cancer

Advanced Science, EarlyView.
It is revealed that a metabolic–stromal loop driven by oxLDL–OLR1–FOXM1–FGF19 signaling promotes progesterone resistance in endometrial cancer. OxLDL activates epithelial–fibroblast crosstalk, enhancing proliferation and hormonal insensitivity. Disruption of this circuit, especially with resveratrol, restores MPA sensitivity, highlighting a potential ...
Xingchen Li, Yue Qi, Yuman Wu, Xinyi Bi, Yiqin Wang, Jiaqi Wang, Jingyuan Wang, Lingpu Zhang, Haihua Xiao, Jianliu Wang   +9 more
wiley   +1 more source

Chromatin remodeling enhances MAP3K8 expression in HAM: a key pathogenesis for therapeutic intervention. [PDF]

Nat Commun
Nakashima M, Nagai K, Takao N, Araya N, Kuze Y, Mizuike J, Tosaka S, Aratani S, Yagishita N, Horibe E, Watanabe T, Sato T, Nannya Y, Suzuki Y, Uchimaru K, Yamagishi M, Yamano Y.   +16 more
europepmc   +1 more source

Effects of Antiandrogens on Chromatin Remodeling and Transcription of the Integrated Mouse Mammary Tumor Virus Promoter

, 2000
Heinz-Joachim List, Catharine L. Smith, Elisabeth D. Martínez, Violaine Harris, Mark Danielsen, Anna T. Riegel   +5 more
openalex   +1 more source

A Pan‐TE Map Reveals the Important Role of Transposable Elements in Gene Expression and Phenotypic Diversity in 2,311 Rapeseed Accessions

Advanced Science, EarlyView.
This study presents the first pan‐transposable element (TE) atlas in rapeseed, profiling over 8 million TEs across 2311 accessions. Integrative analyses reveal that TEs broadly shape gene expression through diverse regulatory mechanisms, with key insertions in BnaA03.FLC and BnaA09.CYP78A9 linked to flowering time and silique development.
Zhiquan Yang, Haiyan Fan, Yifan Chen, Jiawei Li, Minjian Chen, Yingying Tan, Liang Guo, Jintao Li, Kede Liu, Qing‐Yong Yang   +9 more
wiley   +1 more source

NuRD chromatin remodeling contributes to repairing exogenous DSBs in the Caenorhabditis elegans germline. [PDF]

Genetics
Ananthaswamy D, Funes K, Borges T, Roques S, Fassnacht N, El Jamal S, Checchi PM, Lee TW.   +7 more
europepmc   +1 more source

The double CUE domain of chromatin remodelling factor SMARCAD1

, 2012
Philip M. West, West, Philip
openalex   +2 more sources

Hsp90 and p23 Molecular Chaperones Control Chromatin Architecture by Maintaining the Functional Pool of the RSC Chromatin Remodeler [PDF]

, 2016
Frank Echtenkamp, Zlata Gvozdenov, Nicholas L. Adkins, Yang Zhang, Melinda A. Lynch-Day, Shinya Watanabe, Craig L. Peterson, Brian Freeman   +7 more
openalex   +1 more source

Targeting WEE1 in ARID1A/TP53 Concurrent Mutant Colorectal Cancer by Exploiting R‐Loop Accumulation and DNA Repair Deficiencies

Advanced Science, EarlyView.
ARID1A, a SWI/SNF complex component, is frequently mutated in colorectal cancer (CRC). CRC with ARID1A/TP53 concurrent mutations shows marked sensitivity to WEE1 inhibition. ARID1A loss induces R‐loop‐mediated replication stress, impairs ATF3 transcription, and amplifies WEE1i‐induced DNA damage, suggesting a promising therapeutic vulnerability ...
Chi Zhang, Yanjing Zhu, Luoyan Ai, Jingyuan Wang, Shan Yu, Yichen Wang, Xiaojing Xu, Mengling Liu, Yiyi Yu, Mengxuan Zhu, Yutong Liu, Zhenghang Xu, Haojie Zhou, Huishan Li, Qihong Huang, Qing Liu, Ke Peng, Tianshu Liu   +17 more
wiley   +1 more source

Arrieta, A et al Extracellular Cues Signal through Chromatin to Remodel the Sarcomere in Cardiac Hypertrophy, raw data files

Arrieta, Adrian
openalex   +1 more source