Results 241 to 250 of about 578,337 (355)

S3RL: Enhancing Spatial Single‐Cell Transcriptomics With Separable Representation Learning

open access: yesAdvanced Science, EarlyView.
Separable Spatial Representation Learning (S3RL) is introduced to enhance the reconstruction of spatial transcriptomic landscapes by disentangling spatial structure and gene expression semantics. By integrating multimodal inputs with graph‐based representation learning and hyperspherical prototype modeling, S3RL enables high‐fidelity spatial domain ...
Laiyi Fu   +6 more
wiley   +1 more source

Correction: TRIM24 regulates chromatin remodeling and calcium dynamics in cardiomyocytes. [PDF]

open access: yesCell Commun Signal
Neu M   +9 more
europepmc   +1 more source

H1.3 depletion in AML cells prompts H1.2 redistribution, chromatin remodeling and cell cycle defects [PDF]

open access: gold
Clara Tellez-Quijorna   +6 more
openalex   +1 more source

Long non-coding RNA and chromatin remodeling

open access: yesRNA Biology, 2015
Pei Han, C. Chang
semanticscholar   +1 more source

Pirin Transcriptionally Regulates PLA2G4A To Inhibit Ferroptosis in Colorectal Cancer via Lipid Profile Remodeling

open access: yesAdvanced Science, EarlyView.
This study identifies Pirin (PIR), an iron‐binding protein, as a critical ferroptosis suppressor in colorectal cancer through lipid membrane remodeling. PIR, induced by NRF2 during ferroptotic stress, transcriptionally regulates PLA2G4A to shift cellular lipid composition away from ferroptosis‐permissive polyunsaturated phospholipids.
Wei Shi   +10 more
wiley   +1 more source

Structure and function insights into the NuRD chromatin remodeling complex

open access: yesCellular and Molecular Life Sciences, 2015
M. Torchy, A. Hamiche, B. Klaholz
semanticscholar   +1 more source

TP53BP2 Promotes Placental Autophagy and Preeclampsia via G9a and DNMT1 Cooperatively Modulating E2F1

open access: yesAdvanced Science, EarlyView.
G9a, and DNA Methyltransferase1 (DNMT1) cooperatively modulates E2F1 on the promoter of tumor suppressor p53‐binding protein 2 (TP53BP2) increased autophagy in preeclampsia. TP53BP2 promotes autophagy in trophoblasts through DNA methylation and H3K9me2‐mediated transcriptional regulation.
Nan Jiang   +12 more
wiley   +1 more source

The human chromatin remodeling complex p400 restricts HIV-1 transcription in a Tat-dependent manner. [PDF]

open access: yesNucleic Acids Res
Li C   +9 more
europepmc   +1 more source

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