Results 141 to 150 of about 558,654 (343)

Mitochondria‐Specific Protein Delivery by Protease‐Triggered Release in Plants with Single‐Walled Carbon Nanotubes

open access: yesAdvanced Materials Technologies, EarlyView.
Polymer‐coated carbon nanotubes were engineered as protease‐responsive nanocarriers for protein delivery in intact plants. GFP cargo can be released by cytosolic phytaspase cleavage and subsequently targeted to mitochondria via an N‐terminal sequence, enabling controlled intracellular protein delivery without tissue damage and demonstrating stable ...
Simon Sau Yin Law   +3 more
wiley   +1 more source

Amino acid analysis [PDF]

open access: yes, 1974
The process and apparatus for qualitative and quantitative analysis of the amino acid content of a biological sample are presented. The sample is deposited on a cation exchange resin and then is washed with suitable solvents.
Graff, J., Winitz, M.
core   +1 more source

A Dual‐Emissive DNA‐Templated Silver Nanocluster with Near‐Infrared I and II Emission

open access: yesAdvanced Optical Materials, Volume 13, Issue 8, March 13, 2025.
This study presents a dual‐emissive DNA‐stabilized silver nanocluster with a nanosecond‐lived NIR‐I emission band and a microsecond‐lived NIR‐II emission band. Mass spectrometry establishes that the nanocluster has molecular formula (DNA)2[Ag17]11+. DNA sequence variations reveal critical nucleobases for stabilization, and modifications at the DNA 5 ...
Anna Gonzàlez‐Rosell   +6 more
wiley   +1 more source

Temperature‐Dependent Zinc Oxide Cathodoluminescence: Toward Compact Wavelength‐Tunable Solid‐State Photoionization Sources

open access: yesAdvanced Optical Materials, EarlyView.
A proof‐of‐concept of a thermally‐tunable cathodoluminescence‐based light source is demonstrated using a wide‐bandgap z‐cut ZnO crystal as anode, resulting in the ultraviolet (UV) emission peak shifting from 398 nm to ~409 nm (3.115‐3.032 eV). Our results establish the feasibility of a compact, field‐deployable UV source with potential for gas sensing ...
Rui M. R. Pinto   +7 more
wiley   +1 more source

Polyclonal Antibody Production against Mouse Purified IgG2a towards Use in Basic Research

open access: yesResearch in Molecular Medicine, 2016
Background: The ability of polyclonal antibodies to react with many epitopes of an antigen makes them valuable reagents in research and diagnosis.
Zahra Moradi nebrin   +8 more
doaj  

Smart REASSURED Sensors via Machine‐Augmented Printable On‐Paper Arrays

open access: yesAdvanced Sensor Research, EarlyView.
This perspective highlights the emerging role of pattern‐recognition, printable on‐paper sensor arrays for intelligent PoC diagnostics. It discusses how paper's inherent limitations can be overcome through surface modification and scalable printing, and how machine‐learning analysis of cross‐reactive arrays enables multiplexed, low‐cost, and REASSURED ...
Naimeh Naseri, Saba Ranjbar
wiley   +1 more source

Analyzing peptides and proteins by mass spectrometry: principles and applications in proteomics [PDF]

open access: yes, 2012
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/32166The study of proteins has been a key element in biomedicine and biotechnology because of their important role in cell functions or enzymatic activity. Cells are the basic unit of living
Estanyol i Ullate, Josep Maria   +3 more
core   +1 more source

Allosteric Modulation of Pathological Ataxin‐3 Aggregation: A Path to Spinocerebellar Ataxia Type‐3 Therapies

open access: yesAdvanced Science, EarlyView.
This study uncovers a new allosteric site in the Josephin domain of ataxin‐3 targeted by the molecular tweezer CLR01, which modulates protein aggregation, improves synaptic function in neuronal cells, and delays motor dysfunction in animal models.
Alexandra Silva   +28 more
wiley   +1 more source

Hyperandrogenemia Induces Trophoblast Ferroptosis and Early Pregnancy Loss in Patients With PCOS via CMA‐Dependent FTH1 Degradation

open access: yesAdvanced Science, EarlyView.
In PCOS patients with hyperandrogenemia, decreased ferritin heavy chain 1 (FTH1) causes Fe2⁺ overload and ferroptosis in trophoblasts. Androgens induce FTH1 protein degradation via AR‐LAMP2A‐mediated chaperone‐mediated autophagy pathway, leading to placental development disruption and early pregnancy loss. Metformin mitigates androgen‐induced placental
Hanjing Zhou   +10 more
wiley   +1 more source

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