Results 201 to 210 of about 432,155 (258)

Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization

Advanced Science, EarlyView.
This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin, Mengjie Zhang, Wenying Liu, Wenlong Shen, Debao Li, Hongming Miao, Fang Deng, Gang Zhang, Yi Tian, Yi Zhang, Zhihu Zhao, Bing Ni   +11 more
wiley   +1 more source

Innovative applications and future perspectives of chromatography-mass spectrometry in drug research. [PDF]

Front Pharmacol
Cai H, Xing X, Su Y, Yang C.
europepmc   +1 more source

Liquid chromatography-mass spectrometry approach for characterizing sucrose isomers in complex mono-floral honey. [PDF]

Anal Bioanal Chem
Amoah E, Acharya SR, Seth A, Badu-Tawiah AK.   +3 more
europepmc   +1 more source

High-throughput quantitation of acetaldehyde and ethanol in mice using gas chromatography/mass spectrometry positive chemical ionization. [PDF]

Alcohol Clin Exp Res (Hoboken)
Lin YH, Chen C, Wei S, Adrien G, Mackowiak B, Pan H, Fu Y, Maccioni L, Ren T, Zhang L, Hibbeln J, Pawlosky R, Gao B.   +12 more
europepmc   +1 more source

Per- and Polyfluoroalkyl Substances (PFAS) in Michigan: A Novel High-Throughput Method with Liquid Chromatography-Mass Spectrometry (LC-MS/MS) Analysis of 42 PFAS Compounds in Human and Bovine Serum. [PDF]

Toxics
Morrison JM, Carmack DJ, Lockwood-O'Brien SY, Bielicki CA, Feeley JR, Frisk RL, Karrer TA.   +6 more
europepmc   +1 more source

Striatal metabolomic alterations in a mouse model of Parkinson's disease: A comprehensive liquid chromatography-mass spectrometry analysis. [PDF]

IBRO Neurosci Rep
Wu Z, Dai J, Lv B, Su C, Xu D.
europepmc   +1 more source

Single-cell lipidomics: performance evaluation across four liquid chromatography mass spectrometry (LC-MS) systems.

Analyst
von Gerichten J, Saunders KDG, Spick M, Bailey MJ.   +3 more
europepmc   +1 more source

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Supersonic gas chromatography/mass spectrometry

Rapid Communications in Mass Spectrometry, 2001
Abstract A new gas chromatography/mass spectrometry (GC/MS) system was designed and evaluated which we have named ‘Supersonic GC/MS’. It is based on a modification of a commercially available GC/MS system to include a supersonic molecular beam (SMB) MS interface.
A, Amirav, A, Gordin, N, Tzanani
openaire   +2 more sources

Frontal affinity chromatography—mass spectrometry

Nature Protocols, 2007
Frontal affinity chromatography (FAC) is a biophysical method for the discovery and characterization of molecular interactions in a flow-based system. Several different modes of analysis are possible by interfacing to the mass spectrometer, including robust single-compound characterizations as well as high-throughput screening of over 1,000 compounds ...
Ella S M, Ng, Nora W C, Chan, Darren F, Lewis, Ole, Hindsgaul, David C, Schriemer   +4 more
openaire   +2 more sources