Results 11 to 20 of about 2,091,143 (316)
Pitfall in the high-throughput quantification of whole blood cyclosporin A using liquid chromatography-tandem mass spectrometry [PDF]
In a growing number of laboratories the technique of liquid chromatography-tandem mass spectrometry is used for the quantification of cyclosporin A in whole blood, employing cyclosporin D as the internal standard. Cyclosporin A is extensively metabolized
Spöhrer, Ute, Vogeser, Michael
core +2 more sources
The purpose of this study was to develop, optimize, and fully validate a high-sensitivity methodology using UHPLC-MS/MS to simultaneously quantify hesperidin and naringenin in microsamples (100 µL) of murine plasma after intragastric administration of ...
Jesús Alfredo Araujo-León +5 more
doaj +1 more source
Chemical Composition of Leaves, Stem, and Roots of Peperomia pellucida (L.) Kunth
Peperomia pellucida is a species known in the Amazon as “erva-de-jabuti” that has been used in several therapeutic applications based on folk medicine.
Paulo Wender P. Gomes +10 more
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Enhancing the multi-attribute method through an automated and high-throughput sample preparation
The multi-attribute method (MAM), a recent advance in the application of liquid chromatography-mass spectrometry within the pharmaceutical industry, enables the simultaneous monitoring of multiple product quality attributes in a single analytical method.
Pongkwan Sitasuwan +5 more
doaj +1 more source
A liquid chromatography tandem mass spectrometry method for simultaneous analysis of 46 atmospheric particulate-phase persistent organic pollutants and comparison with gas chromatography/mass spectrometry, [PDF]
A novel multi-analyte method for the simultaneous determination of 46 compounds of environmental concern, most of them belonging to the category of persistent organic pollutants, was developed using high-performance liquid chromatography and the results ...
Buiarelli, Francesca +4 more
core +1 more source
Defensive functions and potential ecological conflicts of floral stickiness
Stickiness of vegetative tissues has evolved multiple times in different plant families but is rare and understudied in flowers. While stickiness in general is thought to function primarily as a defense against herbivores, it may compromise mutualistic ...
Alexander Chautá +4 more
doaj +1 more source
An environmentally friendly and high-throughput method for monitoring β-lactam antibiotics in environmental water samples is presented. In this study, an in-lab synthesized graphene oxide supported onto aminopropyl silica (GO@SiO2) sorbent was packed ...
Edvaldo V.S. Maciel +2 more
doaj +1 more source
Hydrophobic interaction chromatography [PDF]
Most proteins and large polypeptides have hydrophobic regions at their surface. These hydrophobic ‘patches’ are due to the presence of the side chains of hydrophobic or non-polar amino acids such as phenylalanine, tryptophan, alanine and methionine ...
Cummins, Phil, O'Connor, Brendan
core +1 more source
Margaritaria nobilis is a shrubby species widely distributed in Brazil from the Amazon to the Atlantic Rainforest. Its bark and fruit are used in the Peruvian Amazon for disinfecting abscesses and as a tonic in pregnancy, respectively, and its leaves are
Johan Carlos C. Santiago +8 more
doaj +1 more source
The COVID-19 pandemic has transformed laboratory management, with a surge in demand for diagnostic tests prompting the adoption of new diagnostic assays and the spread of variant surveillance tools. Rapid antigen tests (RATs) were initially used only for
Annamaria Cucina +6 more
doaj +1 more source

