Results 21 to 30 of about 1,383,122 (318)

Development and Optimization of a High Sensitivity LC-MS/MS Method for the Determination of Hesperidin and Naringenin in Rat Plasma: Pharmacokinetic Approach

open access: yesMolecules, 2020
The purpose of this study was to develop, optimize, and fully validate a high-sensitivity methodology using UHPLC-MS/MS to simultaneously quantify hesperidin and naringenin in microsamples (100 µL) of murine plasma after intragastric administration of ...
Jesús Alfredo Araujo-León   +5 more
doaj   +1 more source

Chemical Composition of Leaves, Stem, and Roots of Peperomia pellucida (L.) Kunth

open access: yesMolecules, 2022
Peperomia pellucida is a species known in the Amazon as “erva-de-jabuti” that has been used in several therapeutic applications based on folk medicine.
Paulo Wender P. Gomes   +10 more
doaj   +1 more source

Analyzes of β-lactam antibiotics by direct injection of environmental water samples into a functionalized graphene oxide-silica packed capillary extraction column online coupled to liquid chromatography tandem mass spectrometry

open access: yesTalanta Open, 2023
An environmentally friendly and high-throughput method for monitoring β-lactam antibiotics in environmental water samples is presented. In this study, an in-lab synthesized graphene oxide supported onto aminopropyl silica (GO@SiO2) sorbent was packed ...
Edvaldo V.S. Maciel   +2 more
doaj   +1 more source

Defensive functions and potential ecological conflicts of floral stickiness

open access: yesScientific Reports, 2022
Stickiness of vegetative tissues has evolved multiple times in different plant families but is rare and understudied in flowers. While stickiness in general is thought to function primarily as a defense against herbivores, it may compromise mutualistic ...
Alexander Chautá   +4 more
doaj   +1 more source

Enhancing the multi-attribute method through an automated and high-throughput sample preparation

open access: yesmAbs, 2021
The multi-attribute method (MAM), a recent advance in the application of liquid chromatography-mass spectrometry within the pharmaceutical industry, enables the simultaneous monitoring of multiple product quality attributes in a single analytical method.
Pongkwan Sitasuwan   +5 more
doaj   +1 more source

Margaritaria nobilis L.F. (Phyllanthaceae): Ethnopharmacology and Application of Computational Tools in the Annotation of Bioactive Molecules

open access: yesMetabolites, 2022
Margaritaria nobilis is a shrubby species widely distributed in Brazil from the Amazon to the Atlantic Rainforest. Its bark and fruit are used in the Peruvian Amazon for disinfecting abscesses and as a tonic in pregnancy, respectively, and its leaves are
Johan Carlos C. Santiago   +8 more
doaj   +1 more source

Pitfall in the high-throughput quantification of whole blood cyclosporin A using liquid chromatography-tandem mass spectrometry [PDF]

open access: yes, 2005
In a growing number of laboratories the technique of liquid chromatography-tandem mass spectrometry is used for the quantification of cyclosporin A in whole blood, employing cyclosporin D as the internal standard. Cyclosporin A is extensively metabolized
Michael Vogeser   +3 more
core   +1 more source

The Suitability of RNA from Positive SARS-CoV-2 Rapid Antigen Tests for Whole Virus Genome Sequencing and Variant Identification to Maintain Genomic Surveillance

open access: yesDiagnostics, 2023
The COVID-19 pandemic has transformed laboratory management, with a surge in demand for diagnostic tests prompting the adoption of new diagnostic assays and the spread of variant surveillance tools. Rapid antigen tests (RATs) were initially used only for
Annamaria Cucina   +6 more
doaj   +1 more source

Development of SPE clean-up procedure for acrylamide determination from potato-based products by GC-MS/MS

open access: yesOpen Agriculture, 2020
The aim of this work was to develop an analytical method for determining acrylamide in potato-based products by gas chromatography and tandem mass spectrometry analysis (GC-MS/MS) using solid-phase extraction (SPE) clean-up.
Negoiță Mioara   +3 more
doaj   +1 more source

Liquid interaction chromatography of polymers

open access: yes, 2022
S.93-129In the last decade, the use of interaction chromatography and hyphenated techniques has become increasingly important for the characterization of polymeric materials.
Radke, Wolfgang, Falkenhagen, J.
core   +1 more source

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